Mid-dermal elastolysis

A rare, acquired, dermis elastic tissue disease characterized by asymptomatic, well-demarcated, symmetric patches and/or plaques of finely wrinkled skin arranged parallel to skin cleavage lines (type I), associated with perifollicular papular protrusions (type II) or with persistent reticular erythema (type III), occurring predominantly on the shoulders, trunk, back, and proximal extremities, associating, on histopathology, a selective loss of elastic tissue in the midreticular dermis. Erythema and/or urticaria may or may not precede wrinkly lesions.



Input patient's signs and symptoms


Narrow down the case reports



Total: 25 (papers)

   


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
1
(17.5%)		 19061655
 [Two cases of papular elastorrhexis].
Pajot C, Le Clec'h C, Hoareau F, Croue A, Verret JL.
Ann Dermatol Venereol. 2008;135(11):757-61.
Anetoderma Scarring
Adult Connective Tissue Diseases Elastic Tissue Hodgkin Disease Homo sapiens Male Middle Aged Nevus Skin Skin Neoplasms
2
(4.0%)		 26362130
 [Mid-dermal elastolysis after insertion of a pacemaker].
Kottler D, Lefevre A, Balme B, Martin-Bourret V, Zaharia D, Skowron F.
Ann Dermatol Venereol. 2015;142(11):680-4.
Allergy
Dermis Elastic Tissue Erythema Homo sapiens Male Middle Aged
2
(4.0%)		 25386304
(4211503)
 Generalized mid dermal elastolysis.
Cruz MJ, Barros AM, Azevedo F.
Dermatol Reports. 2011;3(3):e52.
Eczema
2
(4.0%)		 24447045
 Evolution of granuloma annulare to mid-dermal elastolysis: report of a case and review of the literature.
Lai JH, Murray SJ, Walsh NM.
J Cutan Pathol. 2014;41(5):462-8.
Granuloma
Disease Progression Elastic Tissue Females Granuloma Annulare Homo sapiens Middle Aged
2
(4.0%)		 22780831
 Reticular variant of mid-dermal elastolysis.
Posada C, No N, De La Torre C, Florez A.
Australas J Dermatol. 2013;54(1):69-71.
Papule
Dermis Elastic Tissue Females Homo sapiens Middle Aged Skin Aging
2
(4.0%)		 20827433
(2934769)
 Pseudoxanthoma elasticum papillary dermal elastolysis: a case report.
Alves R, Ferreira L, Vale E, Bordalo O.
Dermatol Res Pract. 2010;2010:.
Papule
2
(4.0%)		 19886960
 Reticular variant of mid-dermal elastolysis after insertion of a pacemaker.
Cutillas E, Ferrando FJ, Marti ME, Mateu A, Rausell N.
Clin Exp Dermatol. 2010;35(5):498-500.
Erythema
Cutis Laxa Erythema Homo sapiens Male
2
(4.0%)		 19363907
 Mid-dermal elastolysis in a patient undergoing chronic hemodialysis.
Eaton PA, Knable AL, Callen JP.
Cutis. 2009;83(3):141-4.
Papule
Dermis Differential Diagnosis Elastic Tissue Homo sapiens Male Middle Aged Renal Dialysis
2
(4.0%)		 19054426
 Perifollicular protrusions--mid-dermal elastolysis.
Volz A, Pfister-Wartha A, Bruckner-Tuderman L, Braun-Falco M.
J Dtsch Dermatol Ges. 2009;7(1):68-9.
Peau d'orange
Adult Connective Tissue Diseases Differential Diagnosis Elastic Tissue Homo sapiens Male Skin Aging
2
(4.0%)		 18806493
 Immunohistochemical investigation of mid-dermal elastolysis with a history of erythema.
Suda T, Hara H, Yoshitake M, Ohbayashi T, Nakamura T, Terui T.
Am J Dermatopathol. 2008;30(5):477-80.
Erythema
CD68 ELN FBLN5 MMP9
Adult Antigens, Differentiation, Myelomonocytic CD Antigens Dermis Elastic Tissue Erythema Extracellular Matrix Proteins Females Histiocytes Homo sapiens Matrix Metalloproteinase 9
        

Phenotype(s) retrieved from Orphanet

    Total: 0

HPO ID Term Frequency


Phenotype(s) retrieved from case reports

    Total: 8

HPO ID Term # of case reports
HP:0032252 Granuloma 5
HP:0010783 Erythema 2
HP:0032026 Anetoderma 2
HP:0200034 Papule 2
HP:0025533 Peau d'orange 1
HP:0030351 Urticarial plaque 1
HP:0100646 Thyroiditis 1
HP:0100699 Scarring 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID