Mid-dermal elastolysis

A rare, acquired, dermis elastic tissue disease characterized by asymptomatic, well-demarcated, symmetric patches and/or plaques of finely wrinkled skin arranged parallel to skin cleavage lines (type I), associated with perifollicular papular protrusions (type II) or with persistent reticular erythema (type III), occurring predominantly on the shoulders, trunk, back, and proximal extremities, associating, on histopathology, a selective loss of elastic tissue in the midreticular dermis. Erythema and/or urticaria may or may not precede wrinkly lesions.



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Total: 25 (papers)

   


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
2
(4.0%)		 8721451
 Mid-dermal elastolysis: a pathological and ultrastructural study of five cases.
Neri I, Patrizi A, Fanti PA, Passarini B, Badiali-De Giorgi L, Varotti C.
J Cutan Pathol. 1996;23(2):165-9.
Urticaria
Adult Elastic Tissue Females Homo sapiens Skin
2
(4.0%)		 7832555
 [Acquired mid-dermal elastolysis. 2 new cases].
Maghraoui S, Grossin M, Crickx B, Blanchet P, Belaich S.
Ann Dermatol Venereol. 1994;121(3):245-6.
Papule
Adult Elastic Tissue Females Homo sapiens
2
(4.0%)		 7763086
 Mid-dermal elastolysis: an ultrastructural and biochemical study.
Fimiani M, Mazzatenta C, Alessandrini C, Paola M, Paola C, Andreassi L.
Arch Dermatol Res. 1995;287(2):152-7.
Urticaria
CTSG
Adult Cathepsin G Cathepsins Cultured Cells Electron Microscopy Females Fibroblasts Homo sapiens Normal Range Pancreatic Elastase Serine Endopeptidases Skin Skin Aging Sunlight Urticaria
2
(4.0%)		 7672990
 [Annular elastolytic giant cell granuloma with a spontaneous healing tendency].
Hermes B, Haas N, Czarnetzki BM.
Hautarzt. 1995;46(7):490-3.
Granuloma
Biopsy Differential Diagnosis Elastic Tissue Electron Microscopy Females Giant Cell Granuloma Granuloma Annulare Homo sapiens Remission, Spontaneous Skin
2
(4.0%)		 1552047
 Mid dermal elastolysis with wrinkling. Report of two cases and review of the literature.
Kim JM, Su WP.
J Am Acad Dermatol. 1992;26(2 Pt 1):169-73.
Macule
Adult Azure Stains Elastic Tissue Females Homo sapiens Skin Aging
        

Phenotype(s) retrieved from Orphanet

    Total: 0

HPO ID Term Frequency


Phenotype(s) retrieved from case reports

    Total: 8

HPO ID Term # of case reports
HP:0032252 Granuloma 5
HP:0010783 Erythema 2
HP:0032026 Anetoderma 2
HP:0200034 Papule 2
HP:0025533 Peau d'orange 1
HP:0030351 Urticarial plaque 1
HP:0100646 Thyroiditis 1
HP:0100699 Scarring 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID