Dermatofibrosarcoma protuberans

Dermatofibrosarcoma protuberans (DFSP) is a rare infiltrating soft tissue sarcoma, generally of low grade malignancy, arising from the dermis of the skin and characteristically associated with a specific chromosomal translocation t(17;22).



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Narrow down the case reports



Total: 244 (papers)

  


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)
PMID
(PMCID)
1
(39.0%)
24728899
Coexistence of giant cell fibroblastoma and encephalocele.
Afroz N, Shamim N, Jain A, Soni M.
BMJ Case Rep. 2014;2014:.
Encephalocele
Dermatofibrosarcoma Head and Neck Neoplasms Homo sapiens Infant Male Skin Neoplasms
2
(30.8%)
15720109
Dermatofibrosarcoma protuberans of the forehead and scalp with involvement of the outer calvarial plate: multistaged repair with the use of skin expanders.
Khachemoune A, Barkoe D, Braun M 3rd, Davison SP.
Dermatol Surg. 2005;31(1):115-9.
Ectropion
Adult Dermatofibrosarcoma Females Forehead Homo sapiens Mohs Surgery Skin Neoplasms Tissue Expansion Devices Wound Healing
3
(23.3%)
9326786
Reconstruction of a large thoracoabdominal wall defect with a flow-through forearm flap and a latissimus dorsi-groin flap.
Chiang YC, Chen FC, Hsieh MJ, Wei FC.
Plast Reconstr Surg. 1997;100(5):1240-4.
Thoracoabdominal wall defect
Abdominal Muscles Dermatofibrosarcoma Homo sapiens Male Middle Aged Skin Neoplasms Surgical Flaps Thoracic Surgical Procedures
4
(20.4%)
7638289
Free tissue failure is not an all-or-none phenomenon.
Weinzweig N, Gonzalez M.
Plast Reconstr Surg. 1995;96(3):648-60.
Osteomyelitis
F2
Adult Females Graft Survival Homo sapiens Male Microcirculation Middle Aged Repeat Surgery Surgical Flaps
4
(20.4%)
3022494
[Malignant fibrous histiocytomas].
Kallweit C, Pfeiff B, Pullmann H.
Z Hautkr. 1986;61(18):1299-302, 1307-8.
Osteomyelitis
Adult Histiocytoma, Benign Fibrous Homo sapiens Leg Male Skin Skin Neoplasms
6
(17.5%)
30775318
Fibrosarcomatous dermatofibrosarcoma protuberans from scar following trauma.
Lee SW, Zaesim A, Jackson A, Borkat M.
Autops Case Rep. 2018;8(4):e2018039.
Soft tissue neoplasm Scarring
6
(17.5%)
30187166
Novel KHDRBS1-NTRK3 rearrangement in a congenital pediatric CD34-positive skin tumor: a case report.
Tallegas M, Fraitag S, Binet A, Orbach D, Jourdain A, Reynaud S, Pierron G, Machet MC, Maruani A.
Virchows Arch. 2019;474(1):111-115.
Neoplasm Connective tissue nevi
CD34 COL1A1 ETV6 KHDRBS1 NTRK3 PDGFB
Adaptor Proteins, Signal Transducing Biomarkers, Tumor Biopsy CD34 Antigens DNA-Binding Proteins Differential Diagnosis Females Gene Fusion Gene Rearrangement Genetic Predisposition to Disease Homo sapiens Immunohistochemistry Infant Magnetic Resonance Imaging Molecular Diagnostic Techniques Neurotrophic Tyrosine Kinase Receptor Type 3 Phenotype Predictive Value of Tests RNA-Binding Proteins Skin Neoplasms
6
(17.5%)
29468850
An unusual clinical presentation of myxoid dermatofibrosarcoma protuberans with a prominent vasculature: A potential pitfall in the diagnosis of myxoid soft tissue tumors.
Tran P, Henderson GP, McLemore M.
J Cutan Pathol. 2018;45(6):419-422.
Lipoma
Adult Dermatofibrosarcoma Differential Diagnosis Homo sapiens Lipoma Male Skin Neoplasms
6
(17.5%)
29416224
(5789558)
A Rare Case of Misdiagnosis: Recurrence of Dermatofibrosarcoma Protuberans That Was Treated Surgicallyas a Keloid.
Ucak M.
Med Arch. 2018;72(1):74-75.
Scarring
Adult Dermatofibrosarcoma Diagnostic Errors Females Homo sapiens Keloid Neoplasm Recurrence, Local Rare Diseases Skin Neoplasms Young Adult
6
(17.5%)
28388964
(5385006)
Breast and pleuropulmonary metastasis of multirecurrent scalp dermatofibrosarcoma protuberans: a case report.
Ouedraogo Nde NA, Ouedraogo NA, Bambara HA, Tiemtore-Kambou BM, Traore F, Zongo N, Ouedraogo MS, Tapsoba GP, Thouraya Chtioui A, Lamien/Sanou A.
J Med Case Rep. 2017;11(1):96.
Atrophic scars
CD34
Adult Alopecia Antineoplastic Agents Biopsy CD34 Antigens Dermatofibrosarcoma Females Homo sapiens Lung Neoplasms Neoplasm Recurrence, Local Pleural Neoplasms Skin Neoplasms
        

Phenotype(s) retrieved from Orphanet

    Total: 6

HPO ID Term Frequency
HP:0001072 Thickened skin Very frequent (99-80%)
HP:0001482 Subcutaneous nodule Very frequent (99-80%)
HP:0008069 Neoplasm of the skin Very frequent (99-80%)
HP:0010783 Erythema Very frequent (99-80%)
HP:0100244 Fibrosarcoma Very frequent (99-80%)
HP:0200042 Skin ulcer Frequent (79-30%)


Phenotype(s) retrieved from case reports

    Total: 33

HPO ID Term # of case reports
HP:0002664 Neoplasm 38
HP:0100242 Sarcoma 34
HP:0012315 Histiocytoma 16
HP:0002861 Melanoma 8
HP:0031459 Soft tissue neoplasm 8
HP:0002860 Squamous cell carcinoma 6
HP:0002671 Basal cell carcinoma 4
HP:0010614 Fibroma 4
HP:0002835 Aspiration 3
HP:0000718 Aggressive behavior 2
HP:0010566 Hamartoma 2
HP:0200034 Papule 2
HP:0001067 Neurofibromas 1
HP:0002019 Constipation 1
HP:0002206 Pulmonary fibrosis 1
HP:0003764 Nevus 1
HP:0009926 Epiphora 1
HP:0010609 Skin tags 1
HP:0012032 Lipoma 1
HP:0012344 Morphea 1
HP:0025637 Vasospasm 1
HP:0030127 Endometriosis 1
HP:0030430 Neuroma 1
HP:0030731 Carcinoma 1
HP:0031111 Cutaneous hamartoma 1
HP:0031925 Rosette 1
HP:0032026 Anetoderma 1
HP:0032252 Granuloma 1
HP:0100537 Fasciitis 1
HP:0100882 Fibrous hamartoma 1
HP:0100898 Connective tissue nevi 1
HP:0200043 Verrucae 1
HP:0500005 Anal pain 1


Causative gene(s) retrieved from Orphanet

    Total: 2

Gene Symbol Gene Name Entrez Gene ID
COL1A1 collagen type I alpha 1 chain 1277
PDGFB platelet derived growth factor subunit B 5155