Clear cell adenocarcinoma of the ovary

Clear cell adenocarcinoma of ovary is a rare, malignant, epithelilal ovarian neoplasm, composed of clear, eosinophilic and hobnail cells displaying variable degrees of tubulocystic, papillary and solid histological patterns, macroscopically appearing as a typically unilateral mass in the ovary which ranges from solid to cystic. Patients are often diagnosed in early stages and usually present with pelvic pain and pressure, an abdominal mass and/or gastrointestinal problems, such as early satiety or bloating. Association with Lynch syndrome has been reported.



Input patient's signs and symptoms


Narrow down the case reports



Total: 30 (papers)

   


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
1
(4.0%)		 16794368
 Persistent and moderate hypercalcemia related to an ovarian clear cell adenocarcinoma: Pre- and postoperative parathyroid hormone related-peptide and 1,25-dihydroxyvitamin D3 levels.
Benit A, Allard J, Rimailho J, Fauvel J, Escourrou G, Vezzosi D, Donadille F, Bennet A, Caron P.
J Endocrinol Invest. 2006;29(5):443-9.
Hypercalcemia
PTH PTHLH
Adenocarcinoma, Clear Cell Females Homo sapiens Hypercalcemia Intraoperative Period Postoperative Period Preoperative Care
1
(4.0%)		 15966371
 [A case of pseudo-meigs syndrome due to ovarian clear cell adenocarcinoma].
Shimizudani N, Senba S, Komiyama M, Hatao H, Ito M, Kioi K, Sudo A, Kishi K, Yagyu H, Oh-ishi S, Nakamura H, Matsuoka T.
Nihon Kokyuki Gakkai Zasshi. 2005;43(4):236-40.
Ascites
Adenocarcinoma, Clear Cell Females Homo sapiens Meigs Syndrome Middle Aged X-Ray Computed Tomography
1
(4.0%)		 12439556
 Complete response to radiation therapy in a patient with chemotherapy-resistant ovarian clear cell adenocarcinoma.
Takai N, Utsunomiya H, Kawano Y, Nasu K, Narahara H, Miyakawa I.
Arch Gynecol Obstet. 2002;267(2):98-100.
Rectovaginal fistula
Adenocarcinoma, Clear Cell Antineoplastic Agents Antineoplastic Agents, Phytogenic Antineoplastic Combined Chemotherapy Protocols Camptothecin Females Homo sapiens Magnetic Resonance Imaging Middle Aged Retreatments
1
(4.0%)		 10637074
 Hypercalcemia due to parathyroid hormone-related protein produced by primary ovarian clear cell adenocarcinoma: case report.
Tsunematsu R, Saito T, Iguchi H, Fukuda T, Tsukamoto N.
Gynecol Oncol. 2000;76(2):218-22.
Hypercalcemia
PTHLH
Adenocarcinoma, Clear Cell Adult Females Homo sapiens Hypercalcemia Neoplasm Proteins Proteins RNA, Messenger
1
(4.0%)		 10500539
 [A case of advanced ovarian clear cell adenocarcinoma responding to cisplatin-cyclophosphamide and paclitaxel-carboplatin].
Iwasaki K, Komuro Y, Masumoto N, Asaoka K, Ishitani K.
Gan To Kagaku Ryoho. 1999;26(10):1483-6.
Pleural effusion
Adenocarcinoma, Clear Cell Antineoplastic Combined Chemotherapy Protocols Drug Administration Schedule Females Homo sapiens Middle Aged Pleural Effusion, Malignant Remission Induction
1
(4.0%)		 9744722
 Ovarian epithelial carcinoma metastatic to the choroid of the eye: prolonged survival with radiation and taxol chemotherapy.
Patsner B.
Eur J Gynaecol Oncol. 1998;19(4):345-6.
Carcinoma
Adenocarcinoma, Clear Cell Choroid Neoplasms Combined Modality Therapy Females Homo sapiens Middle Aged
1
(4.0%)		 9076421
 A pregnant woman with clear cell adenocarcinoma of the ovary arising from endometriosis and with benign and borderline adenofibroma of the clear cell and endometrioid types.
Sugiyama T, Nishida T, Kataoka A, Okura N, Iwanaga S, Yakushiji M.
Eur J Obstet Gynecol Reprod Biol. 1997;72(1):47-50.
Endometriosis
Adenocarcinoma, Clear Cell Adenofibroma Adult Endometrial Neoplasms Endometriosis Females Homo sapiens Pregnancy Pregnancy Complications, Neoplastic
1
(4.0%)		 8678517
 [Successful treatment of clear cell adenocarcinoma of the ovary (OCCA) with a combination of CPT-11 and mitomycin C].
Shimizu Y, Umezawa S, Hasumi K.
Gan To Kagaku Ryoho. 1996;23(5):587-93.
Diarrhea
Adenocarcinoma, Clear Cell Adult Antineoplastic Combined Chemotherapy Protocols Camptothecin Females Homo sapiens Middle Aged Remission Induction Survival Rate
1
(4.0%)		 3983050
 Ovarian carcinoma presenting as pyrexia of unknown origin.
Schofield PM, Kirsop BA, Reginald P, Harington M.
Postgrad Med J. 1985;61(712):177-8.
Ovarian carcinoma
Adenocarcinoma Females Fever of Unknown Origin Homo sapiens Middle Aged
1
(4.0%)		 1582751
 Renal cell carcinoma metastatic to the ovary: a report of three cases emphasizing possible confusion with ovarian clear cell adenocarcinoma.
Young RH, Hart WR.
Int J Gynecol Pathol. 1992;11(2):96-104.
Confusion
Adenocarcinoma Differential Diagnosis Electron Microscopy Females Homo sapiens Kidney Neoplasm Middle Aged Renal Cell Carcinoma
        

Phenotype(s) retrieved from Orphanet

    Total: 0

HPO ID Term Frequency


Phenotype(s) retrieved from case reports

    Total: 10

HPO ID Term # of case reports
HP:0030127 Endometriosis 4
HP:0003072 Hypercalcemia 2
HP:0001289 Confusion 1
HP:0001297 Stroke 1
HP:0002019 Constipation 1
HP:0002027 Abdominal pain 1
HP:0002586 Peritonitis 1
HP:0012735 Cough 1
HP:0031521 Vaginal clear cell adenocarcinoma 1
HP:0100584 Endocarditis 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID