Chondrosarcoma

Chondrosarcoma is a malignant bone tumor arising from cartilaginous tissue, most frequently occuring at the ends of the femur and tibia, the proximal end of the humerus and the pelvis; and presenting with a palpable mass and progressive pain. Chondrosarcoma is usually slow growing at low histological grades and can be well managed by intralesional curettage or en-block wide resection.



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Total: 1212 (papers)

  


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)
PMID
(PMCID)
1
(37.5%)
10440114
A case of ruptured mesenchymal chondrosarcoma of the pancreas.
Komatsu T, Taira S, Matsui O, Takashima T, Note M, Fujita H.
Radiat Med. 1999;17(3):239-41.
Anemia Abdominal pain
Adult Females Homo sapiens Meningeal Neoplasms Mesenchymal Chondrosarcoma Pancreatic Neoplasm Rupture X-Ray Computed Tomography
2
(31.3%)
27163097
(4849246)
Paraneoplastic vasculitis associated to pelvic chondrosarcoma: a case report.
Arvinius C, Gonzalez-Perez A, Garcia-Coiradas J, Garcia-Maroto R, Cebrian-Parra JL.
SICOT J. 2016;2:8.
Visual loss Cholestasis Hepatosplenomegaly
3
(27.6%)
3008975
The rapid onset of cutaneous angiosarcoma after radiotherapy for breast carcinoma.
Otis CN, Peschel R, McKhann C, Merino MJ, Duray PH.
Cancer. 1986;57(11):2130-4.
Leukemia Squamous cell carcinoma
Combined Modality Therapy Females Hemangiosarcoma Homo sapiens Middle Aged Neoplasms, Multiple Primary Neoplasms, Radiation-Induced Noninfiltrating Intraductal Carcinoma Skin Neoplasms
4
(27.5%)
26513897
Carcinosarcoma of the fallopian tube with disappearance of carcinoma cells by neoadjuvant chemotherapy: case study.
Takemoto Y, Ota T, Aoki Y, Ogura K, Ogishima D, Matsumoto T.
Eur J Gynaecol Oncol. 2015;36(5):618-22.
Pleural effusion Pelvic mass
ESR1 KRT20 KRT7 TP53
Carcinosarcoma Chemotherapy, Adjuvant Fallopian Tube Neoplasms Females Homo sapiens Neoadjuvant Therapy
5
(27.3%)
28042016
Spontaneous Intraventricular Hemorrhage: A Rare Presentation of a Skull Base Mesenchymal Chondrosarcoma.
Laghari AA, Javed G, Khan MF, Ahmed SI, Nathani KR, Ahmed R.
World Neurosurg. 2017;99:811.e1-811.e5.
Hydrocephalus Vomiting Intraventricular hemorrhage
Adult Cerebral Hemorrhage Cerebral Ventricles Homo sapiens Hydrocephalus Magnetic Resonance Imaging Male Mesenchymal Chondrosarcoma Skull Base Neoplasms X-Ray Computed Tomography
5
(27.3%)
11974874
[A case of sternal chondrosarcoma with multiple pulmonary embolisms].
Yoshida K, Miyashita N, Nakajima M, Niki Y, Matsushima T.
Nihon Kokyuki Gakkai Zasshi. 2002;40(2):166-70.
Vomiting Intracranial hemorrhage
Chondrosarcoma Homo sapiens Male Middle Aged Pulmonary Embolism Sternum
7
(27.2%)
7951861
A case of metastatic chondrosarcoma of the stomach.
Konishi H, Isetani K, Satoh T, Fukuda S, Kodama T, Kashima K.
J Gastroenterol. 1994;29(4):495-500.
Anemia
Adult Chondrosarcoma Circulating Neoplastic Cells Females Homo sapiens Knee Stomach Neoplasms X-Ray Computed Tomography
8
(26.9%)
29559881
Atypical Presentation of Extramedullary Plasmacytoma.
Wallace E, Stewart Z, Theriot D, Shaffer W, Guillory S, Hanemann M, Danrad R, Spieler B.
Ochsner J. 2018;18(1):101-103.
Glaucoma Hyperlipidemia Erythema
9
(26.6%)
789266
Results obtained with fractionated ifosfamide massive-dose treatment in generalized malignant tumours.
Bruhl P, Gunther U, Hoefer-Janker H, Huls W, Scheef W, Vahlensieck W.
Int J Clin Pharmacol Biopharm. 1976;14(1):29-39.
Leukopenia Nausea and vomiting
Adult Child Females Homo sapiens Male Middle Aged Neoplasms
10
(25.8%)
15094989
Liver metastasis in renal chondrosarcoma.
Mehanna D, Abu-Zidan FM, Rao S.
Singapore Med J. 2004;45(4):183-5.
Jaundice
COX8A
Adult Chondrosarcoma Females Follow-Up Studies Health Risk Assessment Hepatectomy Homo sapiens Kidney Neoplasm Nephrectomy X-Ray Computed Tomography
        

Phenotype(s) retrieved from Orphanet

    Total: 0

HPO ID Term Frequency


Phenotype(s) retrieved from case reports

    Total: 153

HPO ID Term # of case reports
HP:0100242 Sarcoma 114
HP:0002664 Neoplasm 103
HP:0030731 Carcinoma 70
HP:0030431 Osteochondroma 55
HP:0030038 Enchondroma 36
HP:0012315 Histiocytoma 33
HP:0002860 Squamous cell carcinoma 31
HP:0030432 Chondroblastoma 23
HP:0002835 Aspiration 21
HP:0002861 Melanoma 12
HP:0012032 Lipoma 7
HP:0100614 Myositis 7
HP:0002754 Osteomyelitis 6
HP:0002888 Ependymoma 6
HP:0009792 Teratoma 6
HP:0100777 Exostoses 6
HP:0001028 Hemangioma 5
HP:0002094 Dyspnea 5
HP:0002204 Pulmonary embolism 5
HP:0002762 Multiple exostoses 5
HP:0005701 Multiple enchondromatosis 5
HP:0001289 Confusion 4
HP:0001618 Dysphonia 4
HP:0002202 Pleural effusion 4
HP:0003002 Breast carcinoma 4
HP:0012151 Hemothorax 4
HP:0000520 Proptosis 3
HP:0002015 Dysphagia 3
HP:0002176 Spinal cord compression 3
HP:0002668 Paraganglioma 3
HP:0002671 Basal cell carcinoma 3
HP:0003418 Back pain 3
HP:0003419 Low back pain 3
HP:0025615 Abscess 3
HP:0030426 Ossifying fibroma 3
HP:0031492 Epithelial neoplasm 3
HP:0040165 Periostitis 3
HP:0100008 Schwannoma 3
HP:0100749 Chest pain 3
HP:0000651 Diplopia 2
HP:0000718 Aggressive behavior 2
HP:0000819 Diabetes mellitus 2
HP:0000969 Edema 2
HP:0001067 Neurofibromas 2
HP:0001279 Syncope 2
HP:0001638 Cardiomyopathy 2
HP:0001945 Fever 2
HP:0002315 Headache 2
HP:0002756 Pathologic fracture 2
HP:0002897 Parathyroid adenoma 2
HP:0003470 Paralysis 2
HP:0010614 Fibroma 2
HP:0012062 Bone cyst 2
HP:0030065 Primitive neuroectodermal tumor 2
HP:0030078 Lung adenocarcinoma 2
HP:0030433 Osteoid osteoma 2
HP:0031500 Abdominal mass 2
HP:0032252 Granuloma 2
HP:0100774 Hyperostosis 2
HP:0100790 Hernia 2
HP:0200040 Epidermoid cyst 2
HP:0000020 Urinary incontinence 1
HP:0000141 Amenorrhea 1
HP:0000211 Trismus 1
HP:0000316 Hypertelorism 1
HP:0000421 Epistaxis 1
HP:0000572 Visual loss 1
HP:0000622 Blurred vision 1
HP:0000699 Diastema 1
HP:0000704 Periodontitis 1
HP:0000822 Hypertension 1
HP:0000854 Thyroid adenoma 1
HP:0000939 Osteoporosis 1
HP:0000952 Jaundice 1
HP:0001048 Cavernous hemangioma 1
HP:0001250 Seizures 1
HP:0001260 Dysarthria 1
HP:0001269 Hemiparesis 1
HP:0001281 Tetany 1
HP:0001297 Stroke 1
HP:0001324 Muscle weakness 1
HP:0001332 Dystonia 1
HP:0001369 Arthritis 1
HP:0001396 Cholestasis 1
HP:0001433 Hepatosplenomegaly 1
HP:0001605 Vocal cord paralysis 1
HP:0001635 Congestive heart failure 1
HP:0001648 Cor pulmonale 1
HP:0001718 Mitral stenosis 1
HP:0001742 Nasal obstruction 1
HP:0001806 Onycholysis 1
HP:0001903 Anemia 1
HP:0001907 Thromboembolism 1
HP:0001909 Leukemia 1
HP:0001974 Leukocytosis 1
HP:0002013 Vomiting 1
HP:0002027 Abdominal pain 1
HP:0002090 Pneumonia 1
HP:0002099 Asthma 1
HP:0002170 Intracranial hemorrhage 1
HP:0002326 Transient ischemic attack 1
HP:0002341 Cervical cord compression 1
HP:0002647 Aortic dissection 1
HP:0002653 Bone pain 1
HP:0002656 Epiphyseal dysplasia 1
HP:0002749 Osteomalacia 1
HP:0002781 Upper airway obstruction 1
HP:0002797 Osteolysis 1
HP:0002875 Exertional dyspnea 1
HP:0002901 Hypocalcemia 1
HP:0004756 Ventricular tachycardia 1
HP:0004872 Incisional hernia 1
HP:0004947 Arteriovenous fistula 1
HP:0005112 Abdominal aortic aneurysm 1
HP:0005257 Thoracic hypoplasia 1
HP:0005994 Nodular goiter 1
HP:0007838 Progressive ptosis 1
HP:0008200 Primary hyperparathyroidism 1
HP:0008757 Unilateral vocal cord paralysis 1
HP:0010550 Paraplegia 1
HP:0010566 Hamartoma 1
HP:0010615 Angiofibromas 1
HP:0010739 Osteopoikilosis 1
HP:0010866 Abdominal wall defect 1
HP:0011349 Abducens palsy 1
HP:0011695 Cerebellar hemorrhage 1
HP:0012366 Basilar invagination 1
HP:0025232 Bursitis 1
HP:0025247 Dermoid cyst 1
HP:0025388 Thyroid nodule 1
HP:0030061 Neuroectodermal neoplasm 1
HP:0030071 Medulloepithelioma 1
HP:0030746 Intraventricular hemorrhage 1
HP:0030828 Wheezing 1
HP:0030883 Femoroacetabular Impingement 1
HP:0031024 Cylindroma 1
HP:0031246 Nonproductive cough 1
HP:0031459 Soft tissue neoplasm 1
HP:0031501 Pelvic mass 1
HP:0031525 Keratoacanthoma 1
HP:0032043 Odynophagia 1
HP:0032174 Tree-in-bud pattern 1
HP:0100026 Arteriovenous malformation 1
HP:0100537 Fasciitis 1
HP:0100570 Carcinoid tumor 1
HP:0100576 Amaurosis fugax 1
HP:0100582 Nasal polyposis 1
HP:0100605 Neoplasm of the larynx 1
HP:0100615 Ovarian neoplasm 1
HP:0100620 Germinoma 1
HP:0100768 Choriocarcinoma 1
HP:0100817 Renovascular hypertension 1
HP:0410271 Laryngeal hemangioma 1


Causative gene(s) retrieved from Orphanet

    Total: 1

Gene Symbol Gene Name Entrez Gene ID
EXT1 exostosin glycosyltransferase 1 2131