Autoimmune hemolytic anemia, warm type

Warm autoimmune hemolytic anemia is the most common form of autoimmune hemolytic anemia (see this term) defined by the presence of warm autoantibodies against red blood cells (autoantibodies that are active at temperatures between 37-40°C).



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Narrow down the case reports



Total: 15 (papers)

   


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
1
(54.2%)		 27273179
 Fatal warm autoimmune hemolytic anemia in a child due to IgM-type autoantibodies.
Takahashi H, Tanaka F, Sakuma H, Sato M, Inaba S, Kai S.
Pediatr Int. 2016;58(8):744-6.
Jaundice Anemia Fever
Antibodies, Anti-Idiotypic Brain Child Fatal Outcome Homo sapiens Immunoglobulin M Magnetic Resonance Imaging Male
2
(37.5%)		 28870408
 Thyroid storm and warm autoimmune hemolytic anemia.
Moore JA, Gliga L, Nagalla S.
Transfus Apher Sci. 2017;56(4):606-608.
Hyperthyroidism Anemia Vomiting
ERVK-13 HP
Adult Complement C3d Females Homo sapiens Red Blood Cell Transfusion Thyroid Crisis
2
(37.5%)		 9787330
 Fatal autoimmune hemolytic anemia in a child due to warm-reactive immunoglobulin M antibody.
Friedmann AM, King KE, Shirey RS, Resar LM, Casella JF.
J Pediatr Hematol Oncol. 1998;20(5):502-5.
Hepatic failure Anemia
Adrenal Cortex Hormones Adult Autoantibodies Blood Transfusion Child Fatal Outcome Females Homo sapiens Immunoglobulin M Immunosuppressive Agents Syndrome
4
(32.0%)		 15377486
 Sustained response to rituximab of autoimmune hemolytic anemia associated with antiphospholipid syndrome.
Erdozain JG, Ruiz-Irastorza G, Egurbide MV, Aguirre C.
Haematologica. 2004;89(9):ECR34.
Purpura
KRT20
Antibodies, Monoclonal, Murine-Derived Antiphospholipid Syndrome Females Homo sapiens Immunosuppressive Agents Kidney Failure, Chronic Kidney Transplantation Middle Aged Monoclonal Antibodies Postoperative Complications Remission Induction Splenectomy Vasculitis
5
(27.2%)		 28966502
(5607769)
 Rare presentation of mixed autoimmune hemolytic anemia in children: Report of 2 cases.
Rai P, Sharma G, Singh D, Garg J.
J Lab Physicians. 2017;9(4):332-336.
Hemolytic anemia
5
(27.2%)		 26215157
(4515913)
 Autoimmune hemolytic anemia associated with renal urothelial cancer: A case report and literature review.
Isotani S, Horiuchi A, Koja M, Noguchi T, Sugiura S, Shimoyama H, Noma Y, Kitamura K, China T, Tokiwa S, Saito K, Kimura M, Hisasue S, Ide H, Muto S, Yamaguchi R, Horie S.
BMC Urol. 2015;15:75.
Hydronephrosis Hemolytic anemia
Carcinoma, Transitional Cell Differential Diagnosis Homo sapiens Kidney Neoplasm Male Middle Aged Nephrectomy
5
(27.2%)		 11334681
 Intravascular hemolysis by IgA red cell autoantibodies.
Beckers EA, van Guldener C, Overbeeke MA, van Rhenen DJ.
Neth J Med. 2001;58(5):204-7.
Hemolytic anemia
Antibodies, Anti-Idiotypic Autoantibodies Coombs Test Homo sapiens Male
5
(27.2%)		 10553166
 A persistent severe autoimmune hemolytic anemia despite apparent direct antiglobulin test negativization.
Biagi E, Assali G, Rossi F, Jankovic M, Nicolini B, Balduzzi A.
Haematologica. 1999;84(11):1043-5.
Anemia
Coombs Test False Negative Reactions Homo sapiens Infant
5
(27.2%)		 6546059
 Plasma exchange in autoimmune hemolytic anemia (AIHA).
Silberstein LE, Berkman EM.
J Clin Apher. 1983;1(4):238-42.
Hemolytic anemia
Adult Autoantibodies Cell Survival Chromium Radioisotopes Complement 3 Erythrocytes Females Homo sapiens Immunoglobulin M Male Middle Aged Plasma Exchange
5
(27.2%)		 1466193
 IgM autoagglutinins in warm autoimmune hemolytic anemia: a poor prognostic feature.
McCann EL, Shirey RS, Kickler TS, Ness PM.
Acta Haematol. 1992;88(2-3):120-5.
Hemolytic anemia
Adult Agglutinins Autoantibodies Bone Marrow Transplantation Females Homo sapiens Hot Temperature Immunoglobulin M Male Middle Aged
        

Phenotype(s) retrieved from Orphanet

    Total: 16

HPO ID Term Frequency
HP:0000980 Pallor Very frequent (99-80%)
HP:0001890 Autoimmune hemolytic anemia Very frequent (99-80%)
HP:0002315 Headache Very frequent (99-80%)
HP:0002875 Exertional dyspnea Very frequent (99-80%)
HP:0002960 Autoimmunity Very frequent (99-80%)
HP:0012378 Fatigue Very frequent (99-80%)
HP:0001744 Splenomegaly Frequent (79-30%)
HP:0002829 Arthralgia Frequent (79-30%)
HP:0005523 Lymphoproliferative disorder Frequent (79-30%)
HP:0000952 Jaundice Occasional (29-5%)
HP:0001635 Congestive heart failure Occasional (29-5%)
HP:0001649 Tachycardia Occasional (29-5%)
HP:0001945 Fever Occasional (29-5%)
HP:0002725 Systemic lupus erythematosus Occasional (29-5%)
HP:0005550 Chronic lymphatic leukemia Occasional (29-5%)
HP:0012086 Abnormal urinary color Occasional (29-5%)


Phenotype(s) retrieved from case reports

    Total: 4

HPO ID Term # of case reports
HP:0000836 Hyperthyroidism 1
HP:0001873 Thrombocytopenia 1
HP:0001903 Anemia 1
HP:0001971 Hypersplenism 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID