Autoimmune hemolytic anemia, warm type

Warm autoimmune hemolytic anemia is the most common form of autoimmune hemolytic anemia (see this term) defined by the presence of warm autoantibodies against red blood cells (autoantibodies that are active at temperatures between 37-40°C).



Input patient's signs and symptoms


Narrow down the case reports



Total: 15 (papers)

   


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
11
(25.1%)		 17874452
 Hypersplenism induced by splenic vein ligation.
Garibaldi B, King KE, Jaffe JM, Moliterno AR.
Am J Hematol. 2008;83(3):242-4.
Hypersplenism
Blood Transfusion Duodenum Homo sapiens Hypersplenism Male Middle Aged Pancreatectomy
12
(20.5%)		 16398735
 Early-onset autoimmune hemolytic anemia after cladribine therapy for Waldenstrom's macroglobulinemia.
Aslan DL, Peterson BA, Long-Tsai M, Eastlund T.
Transfusion. 2006;46(1):90-4.
Lymphopenia
Antineoplastic Agents Autoantibodies Erythrocytes Homo sapiens Male Middle Aged Waldenstrom Macroglobulinemia
13
(16.3%)		 22435421
 Plasma exchange and rituximab treatment for lenalidomide-associated cold agglutinin disease.
Brauer DL, Edelman B, Rapoport AP, Hess JR, Akpek G.
Transfusion. 2012;52(11):2432-5.
Deep venous thrombosis
ERVK-13
Antibodies, Monoclonal, Murine-Derived Antineoplastic Agents Combined Modality Therapy Homo sapiens Immunologic Factors Male Middle Aged Plasma Exchange
14
(15.4%)		 27062564
 Difficult to swallow: warm autoimmune hemolytic anemia in a Jehovah's Witness treated with hemoglobin concentrate complicated by achalasia.
Epperla N, Strouse C, VanSandt AM, Foy P.
Transfusion. 2016;56(7):1801-6.
Hypertension Achalasia
Blood Substitutes Esophageal Achalasia Hemoglobin Homo sapiens Male
15
(9.2%)		 27834483
 Autoanti-C in a patient with primary sclerosing cholangitis and autoimmune hemolytic anemia: a rare presentation.
Bajpai M, Maheshwari A, Gupta S, Bihari C.
Immunohematology. 2016;32(3):104-107.
Positive direct antiglobulin test
Antibody Specificity Autoantibodies Autoantigens Blood Grouping and Crossmatching Cation Transport Proteins Cholangitis, Sclerosing Coombs Test Females Homo sapiens Membrane Glycoproteins Red Blood Cell Transfusion
        

Phenotype(s) retrieved from Orphanet

    Total: 16

HPO ID Term Frequency
HP:0000980 Pallor Very frequent (99-80%)
HP:0001890 Autoimmune hemolytic anemia Very frequent (99-80%)
HP:0002315 Headache Very frequent (99-80%)
HP:0002875 Exertional dyspnea Very frequent (99-80%)
HP:0002960 Autoimmunity Very frequent (99-80%)
HP:0012378 Fatigue Very frequent (99-80%)
HP:0001744 Splenomegaly Frequent (79-30%)
HP:0002829 Arthralgia Frequent (79-30%)
HP:0005523 Lymphoproliferative disorder Frequent (79-30%)
HP:0000952 Jaundice Occasional (29-5%)
HP:0001635 Congestive heart failure Occasional (29-5%)
HP:0001649 Tachycardia Occasional (29-5%)
HP:0001945 Fever Occasional (29-5%)
HP:0002725 Systemic lupus erythematosus Occasional (29-5%)
HP:0005550 Chronic lymphatic leukemia Occasional (29-5%)
HP:0012086 Abnormal urinary color Occasional (29-5%)


Phenotype(s) retrieved from case reports

    Total: 4

HPO ID Term # of case reports
HP:0000836 Hyperthyroidism 1
HP:0001873 Thrombocytopenia 1
HP:0001903 Anemia 1
HP:0001971 Hypersplenism 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID