Eisenmenger syndrome

Eisenmenger syndrome (ES) is a form of pulmonary arterial hypertension (PAH) associated with unoperated congenital heart disease and is characterized by congenital heart malformations with reversed or bi-directional shunting through an intra-cardiac or intervascular (usually aorto-pulmonary) communication with the development of PAH.



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Narrow down the case reports



Total: 98 (papers)

  


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)
PMID
(PMCID)
91
(5.0%)
27552240
Preoperative Assessment of the Impact of Positive Pressure Ventilation With Noninvasive Positive Pressure Ventilation in a Patient With Eisenmenger Syndrome: A Case Study.
Saito K, Toyama H, Ejima Y, Yamauchi M.
A A Case Rep. 2016;7(9):193-195.
Hypoxemia
Eisenmenger Complex Females Homo sapiens Positive-Pressure Respiration Preoperative Care Young Adult
91
(5.0%)
23423216
First successful heart-lung transplantation in Japan: report of a case.
Sawa Y, Matsumiya G, Shigemura S, Nishi H, Ichikawa H, Minami M, Fukushima N, Inoue M, Ueno T, Sawabatav A, Sakaguchi T, Saito S, Okumura M.
Surg Today. 2013;43(12):1461-6.
Hemoptysis
Adult Double Outlet Right Ventricle Eisenmenger Complex Heart-Lung Transplantation Homo sapiens Japan Male Operative Time
91
(5.0%)
21235613
Use of moderate sedation for a patient with Down syndrome, intellectual disability, and Eisenmenger syndrome: a case report.
Kunimatsu T, Greenan S, Yamashita A, Yamamoto T, Ikeda M.
Spec Care Dentist. 2011;31(1):41-3.
Intellectual disability
Adult Conscious Sedation Dental Care for Disabled Down Syndrome Eisenmenger Complex Homo sapiens Hypnotics and Sedatives Intellectual Disability Male Tooth Extraction
91
(5.0%)
20394258
Use of remifentanil in a patient with Eisenmenger syndrome requiring urgent cesarean section.
Duman A, Sarkilar G, Dayioglu M, Ozden M, Gormus N.
Middle East J Anaesthesiol. 2010;20(4):577-80.
Respiratory distress
Adult Anesthesia, Obstetrical Anesthetics, Combined Anesthetics, Intravenous Eisenmenger Complex Females Homo sapiens Piperidines Pregnancy Pregnancy Complications, Cardiovascular Pregnancy Outcome
91
(5.0%)
17500166
The implications and management of acute odontogenic infection in association with Down and Eisenmenger syndromes and schizophrenia in a rural setting.
Butler DR, Chilvers CR, Cane RJ.
Aust Dent J. 2007;52(1):61-6.
Schizophrenia
Adult Dental Care for Chronically Ill Down Syndrome Eisenmenger Complex Homo sapiens Male Rural Population Schizophrenia Suppurative Periapical Periodontitis
91
(5.0%)
8103043
Sodium clodronate in a patient with the Eisenmenger syndrome, hyperparathyroidism and multiple endocrine adenomatosis.
Hayes D, Condon F, Henry M, Duggan M, Mitchell T.
Ir Med J. 1993;86(4):133.
Hyperparathyroidism
Adenoma Eisenmenger Complex Females Homo sapiens Hyperparathyroidism Middle Aged Multiple Endocrine Neoplasia Pancreatic Neoplasm Parathyroid Neoplasms Pituitary Neoplasms
91
(5.0%)
2019725
[Eisenmenger syndrome and pregnancy. Apropos of a case].
Antoine JM, Bonnardot JP, Vitoux B, Salat-Baroux J.
J Gynecol Obstet Biol Reprod (Paris). 1991;20(1):79-82.
Therapeutic abortion
Adult Eisenmenger Complex Females Homo sapiens Pregnancy Pregnancy Complications, Cardiovascular
91
(5.0%)
1671797
Chronic alpha 1 blockade in a patient with Eisenmenger syndrome.
Watanabe K, Mori C, Haneda N, Inoue M, Kishida K, Hayashi Y, Ozasa H.
Pediatr Cardiol. 1991;12(1):52-3.
Fatigue
Adrenergic alpha-Antagonists Eisenmenger Complex Homo sapiens Male Quinazolines
        

Phenotype(s) retrieved from Orphanet

    Total: 58

HPO ID Term Frequency
HP:0001627 Abnormal heart morphology Very frequent (99-80%)
HP:0002092 Pulmonary arterial hypertension Very frequent (99-80%)
HP:0003546 Exercise intolerance Very frequent (99-80%)
HP:0001324 Muscle weakness Frequent (79-30%)
HP:0001962 Palpitations Frequent (79-30%)
HP:0002875 Exertional dyspnea Frequent (79-30%)
HP:0004755 Supraventricular tachycardia Frequent (79-30%)
HP:0005110 Atrial fibrillation Frequent (79-30%)
HP:0005115 Supraventricular arrhythmia Frequent (79-30%)
HP:0005317 Increased pulmonary vascular resistance Frequent (79-30%)
HP:0012378 Fatigue Frequent (79-30%)
HP:0012418 Hypoxemia Frequent (79-30%)
HP:0030148 Heart murmur Frequent (79-30%)
HP:0000961 Cyanosis Occasional (29-5%)
HP:0001217 Clubbing Occasional (29-5%)
HP:0001254 Lethargy Occasional (29-5%)
HP:0001392 Abnormality of the liver Occasional (29-5%)
HP:0001541 Ascites Occasional (29-5%)
HP:0001609 Hoarse voice Occasional (29-5%)
HP:0001629 Ventricular septal defect Occasional (29-5%)
HP:0001631 Atrial septal defect Occasional (29-5%)
HP:0001643 Patent ductus arteriosus Occasional (29-5%)
HP:0001681 Angina pectoris Occasional (29-5%)
HP:0001694 Right-to-left shunt Occasional (29-5%)
HP:0001708 Right ventricular failure Occasional (29-5%)
HP:0001891 Iron deficiency anemia Occasional (29-5%)
HP:0002098 Respiratory distress Occasional (29-5%)
HP:0002105 Hemoptysis Occasional (29-5%)
HP:0002240 Hepatomegaly Occasional (29-5%)
HP:0003270 Abdominal distention Occasional (29-5%)
HP:0004756 Ventricular tachycardia Occasional (29-5%)
HP:0004840 Hypochromic microcytic anemia Occasional (29-5%)
HP:0005180 Tricuspid regurgitation Occasional (29-5%)
HP:0006695 Atrioventricular canal defect Occasional (29-5%)
HP:0010741 Pedal edema Occasional (29-5%)
HP:0011227 Elevated C-reactive protein level Occasional (29-5%)
HP:0011604 Aortopulmonary window Occasional (29-5%)
HP:0011712 Right bundle branch block Occasional (29-5%)
HP:0012382 Left-to-right shunt Occasional (29-5%)
HP:0012398 Peripheral edema Occasional (29-5%)
HP:0030848 Elevated jugular venous pressure Occasional (29-5%)
HP:0030849 Hepatojugular reflux Occasional (29-5%)
HP:0031138 Abnormal B-type natriuretic peptide level Occasional (29-5%)
HP:0100749 Chest pain Occasional (29-5%)
HP:0000083 Renal insufficiency Very rare (4-1%)
HP:0001279 Syncope Very rare (4-1%)
HP:0001297 Stroke Very rare (4-1%)
HP:0001636 Tetralogy of Fallot Very rare (4-1%)
HP:0001892 Abnormal bleeding Very rare (4-1%)
HP:0002149 Hyperuricemia Very rare (4-1%)
HP:0002321 Vertigo Very rare (4-1%)
HP:0004308 Ventricular arrhythmia Very rare (4-1%)
HP:0005518 Increased mean corpuscular volume Very rare (4-1%)
HP:0006689 Bacterial endocarditis Very rare (4-1%)
HP:0007430 Generalized edema Very rare (4-1%)
HP:0030049 Brain abscess Very rare (4-1%)
HP:0030828 Wheezing Very rare (4-1%)
HP:0100724 Hypercoagulability Very rare (4-1%)


Phenotype(s) retrieved from case reports

    Total: 32

HPO ID Term # of case reports
HP:0000822 Hypertension 18
HP:0001629 Ventricular septal defect 13
HP:0001643 Patent ductus arteriosus 12
HP:0000961 Cyanosis 6
HP:0001694 Right-to-left shunt 4
HP:0001750 Single ventricle 2
HP:0002668 Paraganglioma 2
HP:0012383 Bidirectional shunt 2
HP:0012418 Hypoxemia 2
HP:0000093 Proteinuria 1
HP:0000843 Hyperparathyroidism 1
HP:0001217 Clubbing 1
HP:0001249 Intellectual disability 1
HP:0001511 Intrauterine growth retardation 1
HP:0001562 Oligohydramnios 1
HP:0001667 Right ventricular hypertrophy 1
HP:0001907 Thromboembolism 1
HP:0002094 Dyspnea 1
HP:0002105 Hemoptysis 1
HP:0004756 Ventricular tachycardia 1
HP:0005521 Disseminated intravascular coagulation 1
HP:0006689 Bacterial endocarditis 1
HP:0012108 Open angle glaucoma 1
HP:0012378 Fatigue 1
HP:0012382 Left-to-right shunt 1
HP:0012636 Retinal vein occlusion 1
HP:0025615 Abscess 1
HP:0030049 Brain abscess 1
HP:0031864 Bacteremia 1
HP:0040223 Pulmonary hemorrhage 1
HP:0100603 Toxemia of pregnancy 1
HP:0100753 Schizophrenia 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID