Thymoma

Thymoma is a thymic epithelial neoplasm (TEN; see this term), a rare malignancy that arises from the epithelium of the thymic gland.



Input patient's signs and symptoms


Narrow down the case reports



Total: 1192 (papers)

  


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)
PMID
(PMCID)
1
(50.8%)
19212295
[Thymoma associated with pure red cell aplasia and Kaposi's sarcoma].
Ketata W, Fouzi S, Msaad S, Ben Amira S, Yangui I, Ayoub A.
Rev Mal Respir. 2009;26(1):78-82.
Anemia Pleural effusion Mediastinal lymphadenopathy Kaposi's sarcoma
Anti-Inflammatory Agents Antineoplastic Agents, Phytogenic Antineoplastic Combined Chemotherapy Protocols Females Glucocorticoids Homo sapiens Immunohistochemistry Kaposi Sarcoma Mediastinoscopy Middle Aged Neoplasms, Second Primary Pure Red-Cell Aplasia Radiography, Thoracic Skin Neoplasms Thymoma Thymus Neoplasms Time Factors X-Ray Computed Tomography
2
(50.0%)
18224414
Dramatic remission of anemia after thymectomy in a patient of idiopathic myelofibrosis with thymoma.
Shih YY, Hsiao LT, Yang CF, Wu YC, Chiou TJ.
Int J Hematol. 2008;87(1):56-9.
Splenomegaly Anemia
Anemia Bone Marrow Females Homo sapiens Middle Aged Primary Myelofibrosis Remission Induction Thymectomy Thymoma Thymus Neoplasms
3
(49.7%)
19284608
(2663564)
An unusual presentation of precursor T cell lymphoblastic leukemia/lymphoma with cholestatic jaundice: case report.
Patel KJ, Latif SU, de Calaca WM.
J Hematol Oncol. 2009;2:12.
Jaundice Leukemia Hepatomegaly Dark urine
CD1A CD4 CD5 CD8A SPN SYP
Adult Differential Diagnosis Homo sapiens Jaundice, Obstructive Male Obesity Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Synaptophysin
4
(49.1%)
7647592
Systemic lupus erythematosus and thymoma--a double-edged sword.
Zandman-Goddard G, Lorber M, Shoenfeld Y.
Int Arch Allergy Immunol. 1995;108(1):99-102.
Proteinuria Purpura Anemia
Adult Females Homo sapiens Lupus Erythematosus, Systemic Middle Aged Thymoma Thymus Gland
5
(48.0%)
12233113
[Thymoma with idiopathic thrombocytopenic purpura preceded by mediastinal hemorrhage; report of a case].
Matsuge S, Hosokawa Y, Murakami Y, Satoh K.
Kyobu Geka. 2002;55(10):899-902.
Purpura Splenomegaly Pleural effusion
Females Hemorrhage Homo sapiens Mediastinal Diseases Middle Aged Thymoma Thymus Neoplasms
6
(45.7%)
3970060
Pernicious anemia and giant cell myocarditis. New association.
Kloin JE.
Am J Med. 1985;78(2):355-60.
Diabetes mellitus Vitiligo Anemia Granulomatosis
Anemia, Pernicious Autoimmune Diseases Giant Cell Granuloma Homo sapiens Male Middle Aged Myocarditis Myocardium Necrosis
7
(44.2%)
2556591
[CD8+ agranular lymphocyte proliferative disorder with T-cell receptor beta-chain gene rearrangement associated with thymoma and neutropenia].
Nagashima S, Yamato H, Saito K, Enokihara H, Furusawa S, Shishido H, Kamiyama T, Hirosawa S.
Rinsho Ketsueki. 1989;30(10):1865-70.
Hepatosplenomegaly Neutropenia Pleural effusion
Agranulocytosis Antigens, Differentiation, T-Lymphocyte CD8 Antigens Gene Rearrangement, beta-Chain T-Cell Antigen Rece... Homo sapiens Lymphoproliferative Disorders Male Middle Aged Neutropenia Thymoma Thymus Neoplasms
8
(42.5%)
28744421
(5519314)
Polyparaneoplastic Manifestations of Malignant Thymoma: A Unique Case of Myasthenia, Autoimmune Hepatitis, Pure Red Cell Aplasia, and Keratoconjunctivitis Sicca.
Feinsilber D, Mears KA, Pettiford BL.
Cureus. 2017;9(6):e1374.
Horizontal nystagmus Anemia Hepatitis
8
(42.5%)
22111059
(3214852)
Pure red cell aplasia caused by acute hepatitis a.
Lee TH, Oh SJ, Hong S, Lee KB, Park H, Woo HY.
Chonnam Med J. 2011;47(1):51-3.
Reticulocytopenia Normocytic anemia Viral hepatitis
8
(42.5%)
15025285
Pure red cell aplasia--report of 11 cases from eastern Nepal.
Sinha AK, Agarwal A, Lakhey M, Ansari J, Rani S.
Indian J Pathol Microbiol. 2003;46(3):405-8.
Pallor Normochromic anemia Hepatitis
Adult Bone Marrow Child Child, Preschool Females Hepatitis C Homo sapiens Infant, Newborn Lymphoma, Non-Hodgkin Male Middle Aged Nepal Pure Red-Cell Aplasia Thymoma Thymus Neoplasms
        

Phenotype(s) retrieved from Orphanet

    Total: 30

HPO ID Term Frequency
HP:0004332 Abnormal lymphocyte morphology Very frequent (99-80%)
HP:0045026 Abnormality of the mediastinum Very frequent (99-80%)
HP:0100521 Neoplasm of the thymus Very frequent (99-80%)
HP:0000508 Ptosis Frequent (79-30%)
HP:0000651 Diplopia Frequent (79-30%)
HP:0002015 Dysphagia Frequent (79-30%)
HP:0002094 Dyspnea Frequent (79-30%)
HP:0002716 Lymphadenopathy Frequent (79-30%)
HP:0003473 Fatigable weakness Frequent (79-30%)
HP:0006530 Interstitial pulmonary abnormality Frequent (79-30%)
HP:0012378 Fatigue Frequent (79-30%)
HP:0012735 Cough Frequent (79-30%)
HP:0100749 Chest pain Frequent (79-30%)
HP:0000100 Nephrotic syndrome Occasional (29-5%)
HP:0000217 Xerostomia Occasional (29-5%)
HP:0000988 Skin rash Occasional (29-5%)
HP:0001097 Keratoconjunctivitis sicca Occasional (29-5%)
HP:0001369 Arthritis Occasional (29-5%)
HP:0001376 Limitation of joint mobility Occasional (29-5%)
HP:0001596 Alopecia Occasional (29-5%)
HP:0001701 Pericarditis Occasional (29-5%)
HP:0001876 Pancytopenia Occasional (29-5%)
HP:0001878 Hemolytic anemia Occasional (29-5%)
HP:0002103 Abnormality of the pleura Occasional (29-5%)
HP:0002585 Abnormality of the peritoneum Occasional (29-5%)
HP:0004313 Decreased antibody level in blood Occasional (29-5%)
HP:0010976 B lymphocytopenia Occasional (29-5%)
HP:0012819 Myocarditis Occasional (29-5%)
HP:0100614 Myositis Occasional (29-5%)
HP:0100646 Thyroiditis Occasional (29-5%)


Phenotype(s) retrieved from case reports

    Total: 268

HPO ID Term # of case reports
HP:0030731 Carcinoma 54
HP:0002664 Neoplasm 52
HP:0002721 Immunodeficiency 50
HP:0002835 Aspiration 37
HP:0001903 Anemia 21
HP:0000100 Nephrotic syndrome 19
HP:0009792 Teratoma 16
HP:0100827 Lymphocytosis 16
HP:0012819 Myocarditis 15
HP:0100614 Myositis 13
HP:0002960 Autoimmunity 11
HP:0002094 Dyspnea 10
HP:0002719 Recurrent infections 10
HP:0031690 Opportunistic infection 10
HP:0001909 Leukemia 9
HP:0002861 Melanoma 9
HP:0100570 Carcinoid tumor 9
HP:0002014 Diarrhea 8
HP:0004389 Intestinal pseudo-obstruction 8
HP:0012234 Agranulocytosis 8
HP:0100646 Thyroiditis 8
HP:0100749 Chest pain 8
HP:0001876 Pancytopenia 7
HP:0002090 Pneumonia 7
HP:0002860 Squamous cell carcinoma 7
HP:0000843 Hyperparathyroidism 6
HP:0001873 Thrombocytopenia 6
HP:0002202 Pleural effusion 6
HP:0012735 Cough 6
HP:0100242 Sarcoma 6
HP:0000853 Goiter 5
HP:0001698 Pericardial effusion 5
HP:0001888 Lymphopenia 5
HP:0003003 Colon cancer 5
HP:0005387 Combined immunodeficiency 5
HP:0030357 Small cell lung carcinoma 5
HP:0100521 Neoplasm of the thymus 5
HP:0100726 Kaposi's sarcoma 5
HP:0000099 Glomerulonephritis 4
HP:0000819 Diabetes mellitus 4
HP:0000821 Hypothyroidism 4
HP:0001045 Vitiligo 4
HP:0001370 Rheumatoid arthritis 4
HP:0001875 Neutropenia 4
HP:0002024 Malabsorption 4
HP:0002028 Chronic diarrhea 4
HP:0003002 Breast carcinoma 4
HP:0004859 Amegakaryocytic thrombocytopenia 4
HP:0009830 Peripheral neuropathy 4
HP:0012115 Hepatitis 4
HP:0031273 Shock 4
HP:0031492 Epithelial neoplasm 4
HP:0032118 Retinitis 4
HP:0032252 Granuloma 4
HP:0000822 Hypertension 3
HP:0000829 Hypoparathyroidism 3
HP:0000836 Hyperthyroidism 3
HP:0000975 Hyperhidrosis 3
HP:0001019 Erythroderma 3
HP:0001269 Hemiparesis 3
HP:0001913 Granulocytopenia 3
HP:0002583 Colitis 3
HP:0002668 Paraganglioma 3
HP:0002878 Respiratory failure 3
HP:0002897 Parathyroid adenoma 3
HP:0003072 Hypercalcemia 3
HP:0003198 Myopathy 3
HP:0005523 Lymphoproliferative disorder 3
HP:0010310 Chylothorax 3
HP:0010516 Thymus hyperplasia 3
HP:0010783 Erythema 3
HP:0011947 Respiratory tract infection 3
HP:0012151 Hemothorax 3
HP:0025318 Ovarian carcinoma 3
HP:0025388 Thyroid nodule 3
HP:0031944 Pleural thickening 3
HP:0100820 Glomerulopathy 3
HP:0000112 Nephropathy 2
HP:0000488 Retinopathy 2
HP:0000508 Ptosis 2
HP:0000709 Psychosis 2
HP:0000752 Hyperactivity 2
HP:0000952 Jaundice 2
HP:0000979 Purpura 2
HP:0001298 Encephalopathy 2
HP:0001300 Parkinsonism 2
HP:0001324 Muscle weakness 2
HP:0001369 Arthritis 2
HP:0001396 Cholestasis 2
HP:0001701 Pericarditis 2
HP:0001824 Weight loss 2
HP:0002045 Hypothermia 2
HP:0002107 Pneumothorax 2
HP:0002176 Spinal cord compression 2
HP:0002563 Constrictive pericarditis 2
HP:0002617 Dilatation 2
HP:0002666 Pheochromocytoma 2
HP:0002729 Follicular hyperplasia 2
HP:0002840 Lymphadenitis 2
HP:0002955 Granulomatosis 2
HP:0004936 Venous thrombosis 2
HP:0005363 Humoral immunodeficiency 2
HP:0005435 Impaired T cell function 2
HP:0005987 Multinodular goiter 2
HP:0006532 Recurrent pneumonia 2
HP:0008200 Primary hyperparathyroidism 2
HP:0010566 Hamartoma 2
HP:0012133 Erythroid hypoplasia 2
HP:0012378 Fatigue 2
HP:0012520 Perivascular spaces 2
HP:0025044 Lung abscess 2
HP:0025615 Abscess 2
HP:0030151 Cholangitis 2
HP:0030834 Shoulder pain 2
HP:0031041 Obstruction of the superior vena cava 2
HP:0031047 Paraproteinemia 2
HP:0031625 Pseudoaneurysm 2
HP:0032061 Hypereosinophilia 2
HP:0100001 Malignant mesothelioma 2
HP:0100721 Mediastinal lymphadenopathy 2
HP:0100790 Hernia 2
HP:0000023 Inguinal hernia 1
HP:0000093 Proteinuria 1
HP:0000123 Nephritis 1
HP:0000155 Oral ulcer 1
HP:0000246 Sinusitis 1
HP:0000360 Tinnitus 1
HP:0000388 Otitis media 1
HP:0000529 Progressive visual loss 1
HP:0000643 Blepharospasm 1
HP:0000651 Diplopia 1
HP:0000713 Agitation 1
HP:0000718 Aggressive behavior 1
HP:0000739 Anxiety 1
HP:0000763 Sensory neuropathy 1
HP:0000777 Abnormality of the thymus 1
HP:0000854 Thyroid adenoma 1
HP:0000872 Hashimoto thyroiditis 1
HP:0000962 Hyperkeratosis 1
HP:0000969 Edema 1
HP:0000989 Pruritus 1
HP:0001009 Telangiectasia 1
HP:0001047 Atopic dermatitis 1
HP:0001048 Cavernous hemangioma 1
HP:0001250 Seizures 1
HP:0001254 Lethargy 1
HP:0001271 Polyneuropathy 1
HP:0001279 Syncope 1
HP:0001283 Bulbar palsy 1
HP:0001287 Meningitis 1
HP:0001297 Stroke 1
HP:0001332 Dystonia 1
HP:0001336 Myoclonus 1
HP:0001394 Cirrhosis 1
HP:0001433 Hepatosplenomegaly 1
HP:0001541 Ascites 1
HP:0001548 Overgrowth 1
HP:0001605 Vocal cord paralysis 1
HP:0001635 Congestive heart failure 1
HP:0001658 Myocardial infarction 1
HP:0001659 Aortic regurgitation 1
HP:0001681 Angina pectoris 1
HP:0001709 Third degree atrioventricular block 1
HP:0001818 Paronychia 1
HP:0001878 Hemolytic anemia 1
HP:0001880 Eosinophilia 1
HP:0001894 Thrombocytosis 1
HP:0001897 Normocytic anemia 1
HP:0001907 Thromboembolism 1
HP:0001908 Hypoplastic anemia 1
HP:0001942 Metabolic acidosis 1
HP:0001944 Dehydration 1
HP:0001945 Fever 1
HP:0001970 Tubulointerstitial nephritis 1
HP:0001972 Macrocytic anemia 1
HP:0002019 Constipation 1
HP:0002027 Abdominal pain 1
HP:0002072 Chorea 1
HP:0002098 Respiratory distress 1
HP:0002102 Pleuritis 1
HP:0002110 Bronchiectasis 1
HP:0002113 Pulmonary infiltrates 1
HP:0002148 Hypophosphatemia 1
HP:0002157 Azotemia 1
HP:0002204 Pulmonary embolism 1
HP:0002205 Recurrent respiratory infections 1
HP:0002206 Pulmonary fibrosis 1
HP:0002380 Fasciculations 1
HP:0002411 Myokymia 1
HP:0002486 Myotonia 1
HP:0002580 Volvulus 1
HP:0002647 Aortic dissection 1
HP:0002716 Lymphadenopathy 1
HP:0002754 Osteomyelitis 1
HP:0002863 Myelodysplasia 1
HP:0003139 Panhypogammaglobulinemia 1
HP:0003201 Rhabdomyolysis 1
HP:0003326 Myalgia 1
HP:0003418 Back pain 1
HP:0003470 Paralysis 1
HP:0003552 Muscle stiffness 1
HP:0003701 Proximal muscle weakness 1
HP:0004395 Malnutrition 1
HP:0004756 Ventricular tachycardia 1
HP:0004942 Aortic aneurysm 1
HP:0005113 Aortic arch aneurysm 1
HP:0005263 Gastritis 1
HP:0005353 Recurrent herpes 1
HP:0005374 Cellular immunodeficiency 1
HP:0005425 Recurrent sinopulmonary infections 1
HP:0005994 Nodular goiter 1
HP:0006517 Alveolar proteinosis 1
HP:0006597 Diaphragmatic paralysis 1
HP:0007185 Loss of consciousness 1
HP:0007430 Generalized edema 1
HP:0008208 Parathyroid hyperplasia 1
HP:0008443 Spinal deformities 1
HP:0008978 Necrotizing myopathy 1
HP:0009073 Progressive proximal muscle weakness 1
HP:0010280 Stomatitis 1
HP:0010517 Ectopic thymus tissue 1
HP:0010548 Percussion myotonia 1
HP:0010816 Epidermal nevus 1
HP:0011134 Low-grade fever 1
HP:0011672 Cardiac myxoma 1
HP:0011675 Arrhythmia 1
HP:0011704 Sick sinus syndrome 1
HP:0011787 Central hypothyroidism 1
HP:0011838 Sclerodactyly 1
HP:0011852 Chylopericardium 1
HP:0011854 Hemoperitoneum 1
HP:0011950 Bronchiolitis 1
HP:0011951 Aspiration pneumonia 1
HP:0012032 Lipoma 1
HP:0012114 Endometrial carcinoma 1
HP:0012126 Stomach cancer 1
HP:0012432 Chronic fatigue 1
HP:0012473 Tongue atrophy 1
HP:0012514 Lower limb pain 1
HP:0012578 Membranous nephropathy 1
HP:0025084 Folliculitis 1
HP:0030078 Lung adenocarcinoma 1
HP:0030833 Neck pain 1
HP:0031003 Polyneuritis 1
HP:0031274 Hypovolemic shock 1
HP:0031350 Cardiac sarcoma 1
HP:0031430 Oligoclonal T cell expansion 1
HP:0031459 Soft tissue neoplasm 1
HP:0031500 Abdominal mass 1
HP:0031925 Rosette 1
HP:0032101 Unusual infection 1
HP:0032163 Molluscum contagiosum 1
HP:0032169 Severe infection 1
HP:0040276 Adenocarcinoma of the colon 1
HP:0100008 Schwannoma 1
HP:0100028 Ectopic thyroid 1
HP:0100279 Ulcerative colitis 1
HP:0100620 Germinoma 1
HP:0100724 Hypercoagulability 1
HP:0100742 Vascular neoplasm 1
HP:0100750 Atelectasis 1
HP:0100753 Schizophrenia 1
HP:0100785 Insomnia 1
HP:0100806 Sepsis 1
HP:0100825 Cheilitis 1
HP:0200034 Papule 1
HP:0200120 Chronic active hepatitis 1
HP:0200123 Chronic hepatitis 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID