Total: 7 |
|
PMID (PMCID) | ||
---|---|---|
24015427 |
FEMALE | Adult |
Splenic nodules at autopsy. | ||
Dennis KA, Cheek B, Leroy M, McGoey RR. J La State Med Soc. 2013;165(3):142-4. |
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As such, documentation of GGBs in patients either by pathology or radiology should herald the presence of a systemic disorder such as sickle cell anemia or hemochromatosis wherein portal hypertension and/or congestive splenomegaly are present. | ||
19418550 (4360980) |
MIXED_SAMPLE | Child |
Simultaneous acute splenic sequestration and transient aplastic crisis in children with sickle cell disease. | ||
Yates AM, Hankins JS, Mortier NA, Aygun B, Ware RE. Pediatr Blood Cancer. 2009;53(3):479-81. |
||
Acute splenic sequestration crisis (ASSC) is a hematological emergency in young children with sickle cell disease (SCD), characterized by worsening anemia and splenomegaly, usually with reticulocytosis and thrombocytopenia. | ||
19091280 |
MALE | Adult |
Acute splenic sequestration in an adult with hemoglobin S-C disease. | ||
Rivera-Ruiz M, Varon J, Sternbach GL. Am J Emerg Med. 2008;26(9):1064.e5-8. |
||
The hemoglobinopathy SC is a disease caused by heterozygous-globin chain mutations with over-lapping clinical features of sickle cell disease with changes in the frequency of these manifestations reflected by the combination of characteristics of hemoglobin C and hemoglobin S. In hemoglobin S-C disease, autosplenectomy is rare and splenomegaly usually persists until adulthood;vasoocclusive complications are seen less habitually and become evident at a later time compared with sickle cell disease. | ||
19091280 |
MALE | Adult |
Acute splenic sequestration in an adult with hemoglobin S-C disease. | ||
Rivera-Ruiz M, Varon J, Sternbach GL. Am J Emerg Med. 2008;26(9):1064.e5-8. |
||
The hemoglobinopathy SC is a disease caused by heterozygous-globin chain mutations with over-lapping clinical features of sickle cell disease with changes in the frequency of these manifestations reflected by the combination of characteristics of hemoglobin C and hemoglobin S. In hemoglobin S-C disease, autosplenectomy is rare and splenomegaly usually persists until adulthood;vasoocclusive complications are seen less habitually and become evident at a later time compared with sickle cell disease. | ||
14508799 |
FEMALE | Adult |
Hydroxyurea-induced splenic regrowth in an adult patient with severe hemoglobin SC disease. | ||
Huang Y, Ananthakrishnan T, Eid JE. Am J Hematol. 2003;74(2):125-6. |
||
This case suggests that hydroxyurea might restore some splenic function in functionally asplenic patients with sickle cell anemia or SC disease, but also raises the clinical concern that hydroxyurea may induce splenic regrowth, resulting in symptomatic splenomegaly. | ||
8969620 |
MALE | Adult |
Case report: splenomegaly and splenic sequestration in an adult with sickle cell anemia. | ||
Moll S, Orringer EP. Am J Med Sci. 1996;312(6):299-302. |
||
Splenomegaly in adult patients with homozygous sickle cell anemia (HbSS) is uncommon and splenic sequestration crises are rare. | ||
8969620 |
MALE | Adult |
Case report: splenomegaly and splenic sequestration in an adult with sickle cell anemia. | ||
Moll S, Orringer EP. Am J Med Sci. 1996;312(6):299-302. |
||
Case report: splenomegaly and splenic sequestration in an adult with sickle cell anemia. |