Neuroblastoma

Neuroblastoma is a malignant tumor of neural crest cells, the cells that give rise to the sympathetic nervous system, which is observed in children.

Pheochromocytomas (also known as chromaffin tumors) produce, store, and secrete catecholamines. Pheochromocytomas usually originate from the adrenal medulla but may also develop from chromaffin cells in or about sympathetic ganglia. A common symptom of pheochromocytoma is hypertension owing to release of catecholamines.

Total: 72

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PMID (PMCID)
3035114	MIXED_SAMPLE	Middle Aged
	Iodine-131 MIBG scintigraphy of neuroendocrine tumors other than pheochromocytoma and neuroblastoma.
	Von Moll L, McEwan AJ, Shapiro B, Sisson JC, Gross MD, Lloyd R, Beals E, Beierwaltes WH, Thompson NW. J Nucl Med. 1987;28(6):979-88.
	We conclude that a wide range of neuroendocrine tumors show [131I]MIBG uptake; tumors other than pheochromocytomas and neuroblastomas are less often seen scintigraphically, but in certain cases (e.g., carcinoid and nonsecreting paragangliomas) scintigraphy may be useful in depicting the extent and location of disease and may indicate therapeutic potential.
3035114	MIXED_SAMPLE	Middle Aged
	Iodine-131 MIBG scintigraphy of neuroendocrine tumors other than pheochromocytoma and neuroblastoma.
	Von Moll L, McEwan AJ, Shapiro B, Sisson JC, Gross MD, Lloyd R, Beals E, Beierwaltes WH, Thompson NW. J Nucl Med. 1987;28(6):979-88.
	Metaiodobenzylguanidine (MIBG) locates most pheochromocytomas and neuroblastomas.
3430302	MALE	Infant, Newborn
	Total colonic aganglionosis (Zuelzer-Wilson syndrome) and congenital failure of automatic control of ventilation (Ondine's curse).
	O'Dell K, Staren E, Bassuk A. J Pediatr Surg. 1987;22(11):1019-20.
	The relevant literature regarding the association of these syndromes, the reversal of male to female predominance in total colonic aganglionosis v Hirschsprung's disease, their association with pheochromocytoma and neuroblastoma, and the possible etiologic role of cessation of neural crest cell migration, are discussed.
3585505	MIXED_SAMPLE	Adult
	Uptake of iodine-123 MIBG by pheochromocytomas, paragangliomas, and neuroblastomas: a histopathological comparison.
	Bomanji J, Levison DA, Flatman WD, Horne T, Bouloux PM, Ross G, Britton KE, Besser GM. J Nucl Med. 1987;28(6):973-8.
	Uptake of iodine-123 MIBG by pheochromocytomas, paragangliomas, and neuroblastomas: a histopathological comparison.
2874028	FEMALE	Middle Aged
	Detection of metastatic medullary thyroid cancer with 131I-MIBG scans in Sipple's syndrome.
	Itoh H, Sugie K, Toyooka S, Kawase M, Mukaino S, Hazama F, Endo K, Torizuka K, Nakao K, Imura H. Eur J Nucl Med. 1986;11(12):502-4.
	While 131I-meta-iodobenzyl guanidine (131I-MIBG) scanning has made possible the scintigraphic visualization of pheochromocytoma and neuroblastoma, an accumulation of this agent has recently been reported in medullary thyroid cancer.
3956021	FEMALE	Adult
	Diagnosis and treatment of a carcinoid tumor using iodine-131 meta-iodobenzylguanidine.
	Hoefnagel CA, Den Hartog Jager FC, Van Gennip AH, Marcuse HR, Taal BG. Clin Nucl Med. 1986;11(3):150-2.
	Scintigraphy using I-131 meta-iodobenzylguanidine has been introduced as an effective method to detect pheochromocytomas and neuroblastomas, and the radiopharmaceutical also is applied in therapy of these tumors.
2875869	MIXED_SAMPLE	Middle Aged
	Imaging and uptake mechanism of 131I-meta-iodobenzylguanidine in medullary thyroid carcinoma.
	Oishi S, Sasaki M, Sato T, Hirota Y, Takahashi M. Endocrinol Jpn. 1986;33(3):309-15.
	These findings suggest that MTC can produce catecholamines and therefore, 131I-MIBG is taken up and stored in catecholamine vesicles of MTC, like pheochromocytoma and neuroblastoma.
3158726	FEMALE	Middle Aged
	Metastatic medullary thyroid cancer: localization with iodine-131 metaiodobenzylguanidine.
	Sone T, Fukunaga M, Otsuka N, Morita R, Muranaka A, Yanagimoto S, Tomomitsu T, Nakayama H, Harada T. J Nucl Med. 1985;26(6):604-8.
	Iodine-131 MIBG may prove to be useful for scintigraphic localization and for the treatment of medullary thyroid cancer as in pheochromocytoma and neuroblastoma.
3890187	MIXED_SAMPLE	Child
	Radio-iodobenzylguanidine for the scintigraphic location and therapy of adrenergic tumors.
	McEwan AJ, Shapiro B, Sisson JC, Beierwaltes WH, Ackery DM. Semin Nucl Med. 1985;15(2):132-53.
	In addition to being taken up by pheochromocytomas, meta-iodobenzylguanidine may be used to image neuroblastomas, nonfunctioning paragangliomas, and carcinoid tumors.
6737076	FEMALE
	Scintigraphy of a neuroblastoma with I-131 meta-iodobenzylguanidine.
	Kimmig B, Brandeis WE, Eisenhut M, Bubeck B, Hermann HJ, zum Winkel K. J Nucl Med. 1984;25(7):773-5.
	Because of the kinetic findings and the high uptake of more than 30% of the injected activity, it is likely that the neuroblastoma, by analogy with pheochromocytoma, is susceptible to specific radionuclide therapy.
7245996	MIXED_SAMPLE	Adult
	[Surgical experiences with adrenal tumors (author's transl)].
	Rubay J, Mousset G, Guiot P. Acta Chir Belg. 1980;79(6):415-22.
	This series includes six pheochromocytomas, seven cortical tumors, one adrenal cyst and one neuroblastoma.
490809	FEMALE	Adult
	Neuroblastoma, pheochromocytoma, and renal cell carcinoma. Occurrence in a single patient.
	Fairchild RS, Kyner JL, Hermreck A, Schimke RN. JAMA. 1979;242(20):2210-1.
	Neuroblastoma and pheochromocytoma, despite their common embryologic origin, to our knowledge have not been previously reported as separate tumors in the same patient.