Sarcoidosis

Sarcoidosis is a multisystemic disorder of unknown cause characterized by the formation of immune granulomas in involved organs.

Granuloma

A compact, organized collection of mature mononuclear phagocytes, which may be but is not necessarily accompanied by accessory features such as necrosis.


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PMID (PMCID)
31223420
 FEMALE Middle Aged
Roqai YC, Ajhoun Y, Laaribi N, Belfaiza S, Mouzari Y, El Asri F, Reda K, Oubaaz A.
Pan Afr Med J. 2019;32:132.
Sarcoidosis is a multisystem granulomatous disorders of unknown cause, characterised by the presence of epithelioid granulomas and giant-cell granulomas without caseous necrosis.
31223420
 FEMALE Middle Aged
Roqai YC, Ajhoun Y, Laaribi N, Belfaiza S, Mouzari Y, El Asri F, Reda K, Oubaaz A.
Pan Afr Med J. 2019;32:132.
Sarcoidosis is a multisystem granulomatous disorders of unknown cause, characterised by the presence of epithelioid granulomas and giant-cell granulomas without caseous necrosis.
30956665
 OTHER
A Unique Case of Complete Atrioventricular Block Rapidly Progressing to Diastolic and Systolic Dysfunction in Cardiac Sarcoidosis.
Mbachi CU, Ajiboye O, Ezegwu O, Mba B.
Case Rep Med. 2019;2019:4341098.
Sarcoidosis is a multisystem granulomatous disease that most commonly affects the lungs but can affect other organs including the heart due to granuloma infiltration.
30519468
(6261928)
 OTHER
Coexistent sarcoidosis and lymphangioleiomyomatosis in a patient with cystic lung disease.
Cullivan S, De La Harpe Golden P, Doyle D, Doddakula KK, Burke L, Murphy DM.
Respirol Case Rep. 2019;7(2):e00389.
A video-assisted thoracoscopic surgery (VATS) lung biopsy showed non-caseating granulomas, and serum angiotensin converting enzyme (ACE) was elevated consistent with a diagnosis of pulmonary sarcoidosis.
31258431
 OTHER
Extensive Abdominal Sarcoidosis Without Pulmonary Manifestation.
Alatmi A, Joury AU, Mubarak A.
Ochsner J. 2019;19(2):174-177.
Background: Sarcoidosis is a rare multisystem disease of idiopathic etiology that affects different organs and is characterized histopathologically by the presence of noncaseating granulomas.
31258431
 OTHER
Extensive Abdominal Sarcoidosis Without Pulmonary Manifestation.
Alatmi A, Joury AU, Mubarak A.
Ochsner J. 2019;19(2):174-177.
The histopathology report confirmed the diagnosis of intraabdominal sarcoidosis with the presence of noncaseating granulomas.
30726472
 FEMALE
In-vivo assessment of a case of cutaneous sarcoidosis using reflectance confocal microscopy.
Pasquali P, Gonzalez S, Fortuno A, Freites-Martinez A.
An Bras Dermatol. 2019;94(1):93-95.
The identification of bright beaded-like structures that could correspond to reticulin fibers overlying granulomas, in association with dermoscopy, may be a very useful approach in the diagnosis of sarcoidosis and for the differentiation of this granulomatous entity with superficial cutaneous metastasis.
31275399
 OTHER
Necrotizing Sarcoid Granulomatosis with Pneumothorax.
Pourabdollah M, Saghebi SR, Abdolahi M, Rezaei MS.
Case Rep Med. 2019;2019:4648720.
Necrotizing sarcoid granulomatosis (NSG) is a rare granulomatous pneumonitis which is composed of a background of sarcoidosis-like granulomas, granulomatous vasculitis, and variable amount of necrosis.
30820296
 OTHER
Optic Nerve Head Granuloma, Retinal Vasculitis and Elevated Levels of Angiotensin-converting Enzyme: Dilemma of Forme Fruste Ocular Sarcoidosis.
Bypareddy R, Takkar B, Azad SV, Chawla R, Venkatesh P.
J Ophthalmic Vis Res. 2019;14(1):105-108.
Optic Nerve Head Granuloma, Retinal Vasculitis and Elevated Levels of Angiotensin-converting Enzyme: Dilemma of Forme Fruste Ocular Sarcoidosis.
31263654
 OTHER
Osseous Sarcoidosis with a Solitary Lytic Skull Lesion: A Case Report.
Thirunavukarasu V, Thirunavukarasu C, Willis T, Tsahtsarlis A.
J Neurol Surg Rep. 2019;80(2):e27-e29.
She underwent resection by the neurosurgical team with histopathological study revealing noncaseating granulomas, consistent with sarcoidosis.
31024794
 OTHER
Sarcoid-like reaction associated with renal cell carcinoma - A case report.
Iftikhar A, Cheema MAI, Ramachandran P, Sahni S.
Respir Med Case Rep. 2019;27:100847.
Sarcoidosis is a systemic granulomatous inflammatory disease characterized by non-caseating granulomas that typically afflicts the respiratory system.
31165561
 OTHER
Sarcoidosis-like reaction in metastatic triple negative breast cancer treated by anti-PD-L1.
Lafon M, Blaye C, Kind M, Bechade D, Chassaigne F, Italiano A, Grellety T.
Breast J. 2019;:.
Endoscopic ultrasound-guided fine-needle aspiration of these lymph nodes revealed multiple epitheloid granulomas without caseating necrosis in favour of a sarcoidosis-like reaction.
30852511
 MALE Adult
Systemic sarcoidosis presenting as complete heart block in a patient with normal chest radiography.
Saad Shaukat MH, Fahad F, Weinreb D, Torosoff M.
BMJ Case Rep. 2019;12(3):.
Excision biopsy of the retro-clavicular lymph node revealed non-caseating granulomas consistent with sarcoidosis.
31057065
 OTHER
Uveitis as a window to diagnosis of sarcoidosis - case report and review of the literature.
Dhont S, Leys M, De Sutter E, Alaerts H, Van Moerkercke W.
Acta Clin Belg. 2019;:1-5.
Sarcoidosis is a multisystem disease of unclear etiology with a variable clinical profile characterized by the presence of non-caseating granuloma in involved organs.
30930367
 MALE
[A case of muscle sarcoidosis with hypercalcemia, lower limb muscle strength and without bilateral hilar lymphadenopathy].
Sakamoto S, Suenaga K, Kasama S, Kimura T, Yoshikawa H.
Rinsho Shinkeigaku. 2019;59(4):200-204.
As muscle biopsy revealed non-toxic epithelial cell granulomas, he was diagnosed as muscle sarcoidosis.
28526323
 MALE Adult
18F-FDG PET/CT helps in unmasking the great mimicker: A case of neurosarcoidosis with isolated involvement of the spinal cord.
Gholamrezanezhad A, Mehta L.
Rev Esp Med Nucl Imagen Mol. 2018;37(3):172-174.
The diagnosis of sarcoidosis was supported by identifying non-caseating granuloma in the biopsy of the pulmonary nodule.
27625029
(5849224)
 FEMALE Child
A Novel Mutation in Helical Domain 2 of NOD2 in Sporadic Blau Syndrome.
Jain L, Gupta N, Reddy MM, Mittal R, Barik MR, Panigrahi B, Monie T, Basu S.
Ocul Immunol Inflamm. 2018;26(2):292-294.
She was diagnosed with sporadic Blau syndrome (early-onset sarcoidosis) based on above clinical signs and presence of non-necrotising granuloma on iris biopsy.
27240105
 FEMALE Middle Aged
A case of sarcoidosis with pleural involvement.
Sunnetcioglu A, Sertogullarindan B, Batur A, Bayram I.
Clin Respir J. 2018;12(1):334-336.
Sarcoidosis is a chronic, multisystem inflammatory disorder of unknown etiology that is characterized by noncaseating granulomas.
28785983
 MALE
A curious case of growth failure and hypercalcemia: Questions.
Downie ML, Mulder J, Schneider R, Lim L, Tehrani N, Wasserman JD, Fuchs S, John R, Noone DG, Hebert D.
Pediatr Nephrol. 2018;33(6):991-993.
His eye examination showed uveitis with conjunctival biopsy remarkable for granulomas, which led to pursuit of a diagnosis of possible sarcoidosis.
30024519
(6086523)
 FEMALE Middle Aged
Atypical CT findings of pulmonary sarcoidosis: A case report.
Lee HN, Kim JI, Won K, Song R.
Medicine (Baltimore). 2018;97(29):e11456.
The patient underwent thoracoscopic wedge resection of the nodule and excisional biopsy of the enlarged lymph node to exclude malignancy and non-caseating granulomas consistent with sarcoidosis was confirmed.