Sarcoidosis

Sarcoidosis is a multisystemic disorder of unknown cause characterized by the formation of immune granulomas in involved organs.

Granuloma

A compact, organized collection of mature mononuclear phagocytes, which may be but is not necessarily accompanied by accessory features such as necrosis.


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PMID (PMCID)
30305603
(6196583)
 FEMALE
Hepatic Involvement in Systemic Sarcoidosis.
Ibrahim AM, Bhandari B, Soriano PK, Quader Z, Gao JZ, Shuster D, Mamillapalli CK.
Am J Case Rep. 2018;19:1212-1215.
A thorough workup was performed including a liver biopsy which showed chronic non-necrotizing granulomas consistent with sarcoidosis.
30105085
(6077144)
 OTHER
Hepatic sarcoidosis with atypical radiological manifestations: A case report.
Masuda K, Takenaga S, Morikawa K, Kano A, Ojiri H.
Radiol Case Rep. 2018;13(5):936-939.
Sarcoidosis is a multisystemic inflammatory disease of unknown origin characterized by the formation of noncaseating granulomas and accumulation of inflammatory cells.
25351429
 FEMALE Middle Aged
Inflammatory optic disc edema due to Sarcoidosis mimicking malignant hypertension.
Sharma A, Sagar V, Singla V, Sharma K, Singh R, Singh S, Gupta A.
Int J Rheum Dis. 2018;21(4):895-899.
However, the painful progressive vision loss due to optic disc edema, along with anterior uveitis, and histological proof of non-caseating granulomas on transbronchial lung biopsy clinched the diagnosis of ocular sarcoidosis.
29038921
 FEMALE Middle Aged
Muscular sarcoidosis involving the chest and abdominal walls: case report with MR imaging.
Lee S, Lee IS, Mok J, Song YS, Choi KU.
Skeletal Radiol. 2018;47(3):407-411.
Sarcoidosis is an inflammatory disorder that is characterized by the presence of noncaseating granulomas in tissues, involving many organs and tissues.
30607286
 MALE Middle Aged
Nodular Pulmonary Amyloidosis Mimicking Metastatic Pulmonary Nodules: A case report and review of the literature.
Al-Umairi RS, Al-Lawati F, Al-Busaidi FM.
Sultan Qaboos Univ Med J. 2018;18(3):e393-e396.
Pulmonary nodular amyloidosis can mimic other lung conditions that present with pulmonary nodules, such as metastasis, sarcoidosis and hyalinising granuloma.
29210964
 FEMALE Child
PERIVASCULAR GRANULOMATA IN THE RETINA DEMONSTRATED BY EN FACE OPTICAL COHERENCE TOMOGRAPHY IN A PATIENT WITH BLAU SYNDROME.
Friesen ET, Phasukkijwatana N, Tsui I, Berkenstock MK, Holland GN, Sarraf D.
Retin Cases Brief Rep. 2018;12 Suppl 1:S29-S32.
Similar perivascular granulomata have been noted in the histopathological analysis of ocular sarcoidosis.
30302250
(6170962)
 OTHER
Photodistributed sarcoidosis: a case report and approach to management.
Olteanu C, Worley B, Teo I, Macdonald J.
SAGE Open Med Case Rep. 2018;6:2050313X18796877.
Sarcoidosis is an idiopathic disease, characterized by non-caseating granulomas in multiple organs/tissues.
28856748
 FEMALE Middle Aged
Propionibacterium acnes-associated neurosarcoidosis: A case report with review of the literature.
Yang G, Eishi Y, Raza A, Rojas H, Achiriloaie A, De Los Reyes K, Raghavan R.
Neuropathology. 2018;38(2):159-164.
To the best of our knowledge, this is the first demonstration of P. acnes in sarcoid granulomas of cerebral tissue, and it reinforces the possible link between P. acnes and sarcoidosis.
30203448
 MALE Adult
Rheumatoid-nodule-like cutaneous granuloma associated with recombinase activating gene 1-deficient severe combined immunodeficiency: A rare case.
Van Horn SA, Johnson KM, Childs JM.
J Cutan Pathol. 2018;45(12):940-943.
These cutaneous granulomas are primarily seen in combined variable immunodeficiency, ataxia-telangiectasia, and severe combined immunodeficiency (SCID) and can emulate the reaction patterns seen in sarcoidosis and granuloma annulare.
30203448
 MALE Adult
Rheumatoid-nodule-like cutaneous granuloma associated with recombinase activating gene 1-deficient severe combined immunodeficiency: A rare case.
Van Horn SA, Johnson KM, Childs JM.
J Cutan Pathol. 2018;45(12):940-943.
These cutaneous granulomas are primarily seen in combined variable immunodeficiency, ataxia-telangiectasia, and severe combined immunodeficiency (SCID) and can emulate the reaction patterns seen in sarcoidosis and granuloma annulare.
29984032
(6015673)
 OTHER
Sarcoid of the Upper Humerus Found Incidentally on MR Images Obtained for Work-Up of Rotator Cuff Tear Where Compromised Tissue Quality Was a Concern for Surgical Success.
Henrie TR, Skedros JG.
Case Rep Radiol. 2018;2018:3579527.
A biopsy demonstrated noncaseating granulomas, confirming the diagnosis of sarcoidosis.
29984032
(6015673)
 OTHER
Sarcoid of the Upper Humerus Found Incidentally on MR Images Obtained for Work-Up of Rotator Cuff Tear Where Compromised Tissue Quality Was a Concern for Surgical Success.
Henrie TR, Skedros JG.
Case Rep Radiol. 2018;2018:3579527.
Sarcoidosis is an idiopathic systemic inflammatory disorder characterized histologically by noncaseating granulomas.
29346252
 FEMALE
Sarcoidosis With Pleural Effusion as the Presenting Symptom.
Rivera E, Gesthalter Y, Vardelaan P, Chee A, Majid A.
J Bronchology Interv Pulmonol. 2018;25(2):148-151.
Chest tomography showed mediastinal and bilateral hilar lymphadenopathy, lymph node biopsy with endobronchial ultrasound-guided transbronchial needle aspiration showed non-necrotizing granulomas compatible with sarcoidosis.
30356364
(6176294)
 OTHER
Sarcoidosis and Monoclonal Gammopathy of Undetermined Significance (MGUS): A True Association or Just a Coincidence?
Hassanein M, Karapetyan L, Khan A, Rayamajhi S.
Case Rep Hematol. 2018;2018:3790760.
Sarcoidosis is a systemic inflammatory disease characterized by the presence of noncaseating granulomas in different organs.
29483997
(5816331)
 OTHER
Sarcoidosis in A. C. Milan (1899)?
Tchernev G, Lotti T, Wollina U, Cardoso JC, Popova LV, Maximov GK, Lozev I, Terziev I.
Open Access Maced J Med Sci. 2018;6(1):99-102.
The sarcoid granuloma, even when it is sterile, should not be considered as the equivalent of sarcoidosis, i.e., sarcoidosis as an autonomous disease.
29483997
(5816331)
 OTHER
Sarcoidosis in A. C. Milan (1899)?
Tchernev G, Lotti T, Wollina U, Cardoso JC, Popova LV, Maximov GK, Lozev I, Terziev I.
Open Access Maced J Med Sci. 2018;6(1):99-102.
Distinguishing between sarcoidosis and sarcoid-like reactions (sarcoid - type granulomas) is not currently a medical "gold standard" and is not implemented in clinical practice.
29483997
(5816331)
 OTHER
Sarcoidosis in A. C. Milan (1899)?
Tchernev G, Lotti T, Wollina U, Cardoso JC, Popova LV, Maximov GK, Lozev I, Terziev I.
Open Access Maced J Med Sci. 2018;6(1):99-102.
The sarcoid granuloma, even when it is sterile, should not be considered as the equivalent of sarcoidosis, i.e., sarcoidosis as an autonomous disease.
30558069
 FEMALE Middle Aged
Sarcoidosis of the medulla oblongata causing intractable hiccoughs and numbness of extremities: A case report.
Chen XY, Ren ZC, Huang XJ.
Medicine (Baltimore). 2018;97(50):e13667.
Sarcoidosis is a multisystem disorder characterized by noncaseating granulomas.
30558069
 FEMALE Middle Aged
Sarcoidosis of the medulla oblongata causing intractable hiccoughs and numbness of extremities: A case report.
Chen XY, Ren ZC, Huang XJ.
Medicine (Baltimore). 2018;97(50):e13667.
Transbranchial needle aspiration biopsy revealed noncaseating granuloma consisting of epithelioid cells, lymphocytes, and rare multinucleated giant cells which was consistent with sarcoidosis.
29931995
 FEMALE
Sarcoidosis onset simulating a unique hepatic metastasis.
Dieguez Castillo C, Martin-Lagos Maldonado A, Rios Pelegrina RM, Diaz Alcazar MDM, Roa Colomo A, Ruiz Escolano E.
Rev Esp Enferm Dig. 2018;110(7):466-467.
Sarcoidosis is a systemic granulomatous disease with an uncertain etiology, characterized by the production of non-necrotizing granulomas.