| Rank (Similarity) |
PMID (PMCID) |
|
|---|---|---|
| 1 (56.2%) |
22525637 |
[Autoimmune lymphoproliferative syndrome]. Rodrigues V, Conde M, Figueiredo A, Vasconcelos J, Dias A. Acta Med Port. 2011;24(5):833-6. |
| Splenomegaly Anemia Fever | ||
| CD4 CD8A FASLG IL10 | ||
| Autoimmune Lymphoproliferative Syndrome Child Homo sapiens Male | ||
| 2 (55.1%) |
25972287 |
Autoimmune Lymphoproliferative Syndrome with Red Cell Aplasia. Meena KR, Bisht S, Tamaria KC. Indian J Pediatr. 2015;82(12):1172-4. |
| Hepatosplenomegaly Reticulocytopenia Normocytic anemia Abnormal lymphocyte apoptosis | ||
| Autoimmune Lymphoproliferative Syndrome Child Differential Diagnosis Drug Administration Schedule Females Glucocorticoids Hematologic Tests Hepatomegaly Homo sapiens Immunologic Factors Immunologic Tests Lymphadenopathy Pure Red-Cell Aplasia Splenomegaly | ||
| 2 (55.1%) |
25619350 |
[A case of autoimmune lymphoproliferactive syndrome and literature review]. Liu L, Hu J, Ma J, Li X, Li F, Li C. Zhonghua Er Ke Za Zhi. 2014;52(12):923-6. |
| Hepatosplenomegaly Hemolytic anemia Fever | ||
| CD4 CD8A IGHA1 | ||
| Autoimmune Lymphoproliferative Syndrome CD95 Antigens Cell Count Homo sapiens Infant Male T-Lymphocyte Subsets | ||
| 4 (50.9%) |
26679669 |
[Autoimmune lymphoproliferative syndrome: a case report and literature review]. Sun JP, Lu XT, Zhao WH, Hua Y. Beijing Da Xue Xue Bao Yi Xue Ban. 2015;47(6):1022-7. |
| Splenomegaly Hemolytic anemia Hepatomegaly | ||
| c|SUB|A|309|C | ||
| Antibodies, Antinuclear Autoimmune Lymphoproliferative Syndrome Homo sapiens Infant Male Splenomegaly T-Lymphocyte Thrombocytopenia | ||
| 4 (50.9%) |
24906264 |
Autoimmune lymphoproliferative syndrome with neonatal onset. Naveed M, Khamis Butt UB, Mannan J. J Coll Physicians Surg Pak. 2014;24 Suppl 2:S124-6. |
| Hepatosplenomegaly Splenomegaly Anemia | ||
| Autoimmune Lymphoproliferative Syndrome Fatal Outcome Females Hepatomegaly Homo sapiens Infant Infant, Newborn Male Splenomegaly T-Lymphocyte Thrombocytopenia | ||
| 6 (50.0%) |
26041772 |
A Novel and Likely Inherited Lymphoproliferative Disease in British Shorthair Kittens. Aberdein D, Munday JS, Fairley RA, Vernau W, Thompson KG. Vet Pathol. 2015;52(6):1176-82. |
| Splenomegaly Hemolytic anemia | ||
| CD4 CD8A | ||
| Animals Cat Diseases Felis catus Females Genetic Predisposition to Disease Lymphadenopathy Lymphoproliferative Disorders Male Splenomegaly T-Cell Lymphoma | ||
| 6 (50.0%) |
21961487 |
Glucocorticoid-resistant Evans' syndrome successfully controlled with low-dose cyclosporine. Janic D, Krivokapic-Dokmanovic L, Jovanovic N, Lazic J, Rodic P, Jankovic S. Int J Clin Pharmacol Ther. 2011;49(10):622-5. |
| Splenomegaly Coombs-positive hemolytic anemia | ||
| CD4 CD8A | ||
| Child Glucocorticoids Homo sapiens Immunosuppressive Agents Male Thrombocytopenia | ||
| 6 (50.0%) |
19499578 |
Splenectomy in two children with autoimmune lymphoproliferative syndrome and massive splenomegaly. Glerup M, Thelle T, Gronbaek K, Hasle H. Pediatr Blood Cancer. 2009;53(6):1124-6. |
| Splenomegaly Anemia | ||
| Females Growth Homo sapiens Infant Lymphoproliferative Disorders Male Splenectomy Splenomegaly | ||
| 6 (50.0%) |
18070632 |
Autoimmune lymphoproliferative syndrome in a patient with a new minimal deletion in the death domain of the FAS gene. Gualco G, van den Berg A, Koopmans S, Bacchi LM, Carneiro SS, Ruiz E Jr, Vecchi AP, Chan JK. Hum Pathol. 2008;39(1):137-41. |
| Splenomegaly Anemia | ||
| c|DEL|930|TGCT | ||
| Autoimmune Diseases CD95 Antigens Child Fas-Associated Death Domain Protein Homo sapiens Lymphoproliferative Disorders Male Sequence Deletion | ||
| 10 (48.9%) |
30080751 |
Weekly Rituximab Followed by Monthly Rituximab Treatment for Autoimmune Disease Associated With RAS-associated Autoimmune Leukoproliferative Disease. Toyoda H, Deguchi T, Iwamoto S, Kihira K, Hori H, Komada Y, Hirayama M. J Pediatr Hematol Oncol. 2018;40(8):e516-e518. |
| Hepatosplenomegaly Hemolytic anemia | ||
| KRAS | ||
| c|SUB|G|13|C;RS#:121913535 | ||
| Anemia, Hemolytic Child Females Homo sapiens Mutation Proto-Oncogene Proteins p21(ras) |
Total: 67
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0001744 | Splenomegaly | Very frequent (99-80%) |
| HP:0002716 | Lymphadenopathy | Very frequent (99-80%) |
| HP:0002730 | Chronic noninfectious lymphadenopathy | Very frequent (99-80%) |
| HP:0002960 | Autoimmunity | Very frequent (99-80%) |
| HP:0000978 | Bruising susceptibility | Frequent (79-30%) |
| HP:0001890 | Autoimmune hemolytic anemia | Frequent (79-30%) |
| HP:0001892 | Abnormal bleeding | Frequent (79-30%) |
| HP:0001904 | Neutropenia in presence of anti-neutropil antibodies | Frequent (79-30%) |
| HP:0001971 | Hypersplenism | Frequent (79-30%) |
| HP:0001973 | Autoimmune thrombocytopenia | Frequent (79-30%) |
| HP:0002240 | Hepatomegaly | Frequent (79-30%) |
| HP:0002851 | Elevated proportion of CD4-negative, CD8-negative, alpha-beta regulatory T cells | Frequent (79-30%) |
| HP:0003237 | Increased circulating IgG level | Frequent (79-30%) |
| HP:0005404 | Increased B cell count | Frequent (79-30%) |
| HP:0010702 | Increased antibody level in blood | Frequent (79-30%) |
| HP:0030782 | Abnormal serum interleukin level | Frequent (79-30%) |
| HP:0000099 | Glomerulonephritis | Occasional (29-5%) |
| HP:0001025 | Urticaria | Occasional (29-5%) |
| HP:0001880 | Eosinophilia | Occasional (29-5%) |
| HP:0001888 | Lymphopenia | Occasional (29-5%) |
| HP:0001923 | Reticulocytosis | Occasional (29-5%) |
| HP:0002633 | Vasculitis | Occasional (29-5%) |
| HP:0002848 | Specific anti-polysaccharide antibody deficiency | Occasional (29-5%) |
| HP:0002850 | Decreased circulating total IgM | Occasional (29-5%) |
| HP:0002923 | Rheumatoid factor positive | Occasional (29-5%) |
| HP:0003212 | Increased circulating total IgE level | Occasional (29-5%) |
| HP:0003261 | Increased circulating IgA level | Occasional (29-5%) |
| HP:0003453 | Antineutrophil antibody positivity | Occasional (29-5%) |
| HP:0003493 | Antinuclear antibody positivity | Occasional (29-5%) |
| HP:0003613 | Antiphospholipid antibody positivity | Occasional (29-5%) |
| HP:0004315 | Decreased circulating IgG level | Occasional (29-5%) |
| HP:0004844 | Coombs-positive hemolytic anemia | Occasional (29-5%) |
| HP:0005407 | Decreased proportion of CD4-positive T cells | Occasional (29-5%) |
| HP:0012115 | Hepatitis | Occasional (29-5%) |
| HP:0012189 | Hodgkin lymphoma | Occasional (29-5%) |
| HP:0012190 | T-cell lymphoma | Occasional (29-5%) |
| HP:0012191 | B-cell lymphoma | Occasional (29-5%) |
| HP:0012539 | Non-Hodgkin lymphoma | Occasional (29-5%) |
| HP:0030080 | Burkitt lymphoma | Occasional (29-5%) |
| HP:0031392 | Abnormal proportion of CD4 T cells | Occasional (29-5%) |
| HP:0031393 | Abnormal proportion of CD8 T cells | Occasional (29-5%) |
| HP:0040126 | Abnormal vitamin B12 level | Occasional (29-5%) |
| HP:0100646 | Thyroiditis | Occasional (29-5%) |
| HP:0100827 | Lymphocytosis | Occasional (29-5%) |
| HP:0000083 | Renal insufficiency | Very rare (4-1%) |
| HP:0000554 | Uveitis | Very rare (4-1%) |
| HP:0000854 | Thyroid adenoma | Very rare (4-1%) |
| HP:0001250 | Seizures | Very rare (4-1%) |
| HP:0001369 | Arthritis | Very rare (4-1%) |
| HP:0001402 | Hepatocellular carcinoma | Very rare (4-1%) |
| HP:0001789 | Hydrops fetalis | Very rare (4-1%) |
| HP:0002113 | Pulmonary infiltrates | Very rare (4-1%) |
| HP:0002206 | Pulmonary fibrosis | Very rare (4-1%) |
| HP:0002315 | Headache | Very rare (4-1%) |
| HP:0002583 | Colitis | Very rare (4-1%) |
| HP:0002671 | Basal cell carcinoma | Very rare (4-1%) |
| HP:0002725 | Systemic lupus erythematosus | Very rare (4-1%) |
| HP:0002890 | Thyroid carcinoma | Very rare (4-1%) |
| HP:0005263 | Gastritis | Very rare (4-1%) |
| HP:0005528 | Bone marrow hypocellularity | Very rare (4-1%) |
| HP:0008069 | Neoplasm of the skin | Very rare (4-1%) |
| HP:0008209 | Premature ovarian insufficiency | Very rare (4-1%) |
| HP:0010619 | Fibroadenoma of the breast | Very rare (4-1%) |
| HP:0011107 | Recurrent aphthous stomatitis | Very rare (4-1%) |
| HP:0012490 | Panniculitis | Very rare (4-1%) |
| HP:0031020 | Bone marrow hypercellularity | Very rare (4-1%) |
| HP:0100648 | Neoplasm of the tongue | Very rare (4-1%) |
Total: 27
| HPO ID | Term | # of case reports |
|---|---|---|
| HP:0002716 | Lymphadenopathy | 18 |
| HP:0001744 | Splenomegaly | 16 |
| HP:0002960 | Autoimmunity | 9 |
| HP:0008940 | Generalized lymphadenopathy | 3 |
| HP:0001433 | Hepatosplenomegaly | 2 |
| HP:0001873 | Thrombocytopenia | 2 |
| HP:0005523 | Lymphoproliferative disorder | 2 |
| HP:0000952 | Jaundice | 1 |
| HP:0001025 | Urticaria | 1 |
| HP:0001369 | Arthritis | 1 |
| HP:0001747 | Accessory spleen | 1 |
| HP:0001876 | Pancytopenia | 1 |
| HP:0001880 | Eosinophilia | 1 |
| HP:0002090 | Pneumonia | 1 |
| HP:0002240 | Hepatomegaly | 1 |
| HP:0002721 | Immunodeficiency | 1 |
| HP:0002840 | Lymphadenitis | 1 |
| HP:0003419 | Low back pain | 1 |
| HP:0025289 | Cervical lymphadenopathy | 1 |
| HP:0030886 | Abnormal lymphocyte apoptosis | 1 |
| HP:0031273 | Shock | 1 |
| HP:0032204 | Chronic active Epstein-Barr virus infection | 1 |
| HP:0100242 | Sarcoma | 1 |
| HP:0100537 | Fasciitis | 1 |
| HP:0100614 | Myositis | 1 |
| HP:0100665 | Angioedema | 1 |
| HP:0100827 | Lymphocytosis | 1 |