Acute panmyelosis with myelofibrosis




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Narrow down the case reports



Total: 63 (papers)

   


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Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
11
(45.3%)		 951181
 [Acute or subacute myelofibrosis].
Briere J, Castro-Malaspina H, Briere JF, Bernard J.
Nouv Rev Fr Hematol. 1976;16(1):3-22.
Splenomegaly Leukemia Fever
P4HTM
Acute Disease Adult Alkaline Phosphatase Bone Marrow Examination Cell Survival Erythrocytes Erythropoiesis Females Homo sapiens Leukocytes Male Middle Aged Primary Myelofibrosis
12
(39.1%)		 24192103
 [Acute panmyelosis with myelofibrosis: a rare cause of pancytopenia].
Fale C, Araujo A, Lourenco S, Pais M.
Acta Med Port. 2013;26(5):613-6.
Splenomegaly Pancytopenia
Homo sapiens Leukemia, Myelocytic, Acute Male Pancytopenia Primary Myelofibrosis
12
(39.1%)		 6586278
 Megakaryoblastic transformation in myeloproliferative disorders.
Jacobs P, le Roux I, Jacobs L.
Cancer. 1984;54(2):297-302.
Splenomegaly Thrombocytosis
Blood Cell Count Blood Platelets Erythrocytes Females Histocytochemistry Homo sapiens Leukemia, Myelocytic, Acute Male Megakaryocytes Middle Aged
12
(39.1%)		 918796
 Acute of fulminating myelofibrosis.
Dalby AJ, Dubovsky D, Jacobs P.
S Afr Med J. 1977;52(13):531-4.
Splenomegaly Myelofibrosis
Acute Disease Adrenal Cortex Hormones Adult Anti-Bacterial Agents Females Homo sapiens Male Middle Aged Primary Myelofibrosis
15
(38.0%)		 7115954
 Karyotypic polymorphism in acute myelofibrosis.
Shah I, Mayeda K, Koppitch F, Mahmood S, Nemitz B.
Blood. 1982;60(4):841-4.
Hepatosplenomegaly Pancytopenia
Acute Disease Blood Transfusion Bone Marrow Cells Chromosomes, Human, 1-3 Chromosomes, Human, 4-5 Chromosomes, Human, 6-12 and X Erythrocytes Genetic Polymorphism Homo sapiens Male Megakaryocytes Middle Aged Primary Myelofibrosis Trisomy
15
(38.0%)		 7074567
 Idiopathic acquired sideroblastic anemia terminating in acute myelosclerosis.
Butler WM, Taylor HG, Viswanathan U.
Cancer. 1982;49(12):2497-9.
Hepatosplenomegaly Pancytopenia
Acute Disease Homo sapiens Male Primary Myelofibrosis
15
(38.0%)		 3758840
 Acute megakaryocytic myelosis preceded by myelodysplasia. Report of a case and review of the literature.
Fohlmeister I, Stratmann F, Hock A, Reis HE.
Haematologia (Budap). 1986;19(2):151-60.
Hepatosplenomegaly Pancytopenia
Bone Marrow Homo sapiens Lactate Dehydrogenase Male Megakaryocytes Middle Aged Primary Myelofibrosis
15
(38.0%)		 572695
 Megakaryoblastic leukaemia (acute myelofibrosis): a report of three cases.
den Ottolander GJ, te Velde J, Brederoo P, Geraedts JP, Slee PH, Willemze R, Zwaan FE, Haak HL, Muller HP, Bieger R.
Br J Haematol. 1979;42(1):9-20.
Hepatosplenomegaly Pancytopenia
Acute Disease Adult Bone Marrow Electron Microscopy Females Homo sapiens Isoenzymes Lactate Dehydrogenase Male Megakaryocytes Middle Aged Thrombocythemia, Essential
19
(37.6%)		 3605072
 A distinct subtype of idiopathic myelofibrosis with bone marrow features mimicking hairy cell leukemia: evidence of an autoimmune pathogenesis.
Hasselbalch H, Jans H, Nielsen PL.
Am J Hematol. 1987;25(2):225-9.
Leukemia Poikilocytosis
Adult Autoimmune Diseases Bone Marrow Bone Marrow Cells Differential Diagnosis Females Hairy Cell Leukemia Homo sapiens Primary Myelofibrosis
20
(31.4%)		 10723241
 [Werner's syndrome associated with acute myelofibrosis].
Shimura K, Shimazaki C, Okamoto A, Takahashi R, Hirai H, Sumikuma T, Ashihara E, Inaba T, Fujita N, Komatsu S, Hirano S, Nakagawa M.
Rinsho Ketsueki. 2000;41(2):123-8.
Pancytopenia Anemia Pneumonia
TGFB1
Acute Disease Fatal Outcome Homo sapiens Male Middle Aged Primary Myelofibrosis Werner Syndrome
        

Phenotype(s) retrieved from Orphanet

    Total: 15

HPO ID Term Frequency
HP:0001876 Pancytopenia Very frequent (99-80%)
HP:0011974 Myelofibrosis Very frequent (99-80%)
HP:0001324 Muscle weakness Frequent (79-30%)
HP:0012129 Abnormality of bone marrow stromal cells Frequent (79-30%)
HP:0012143 Abnormal megakaryocyte morphology Frequent (79-30%)
HP:0012378 Fatigue Frequent (79-30%)
HP:0031020 Bone marrow hypercellularity Frequent (79-30%)
HP:0003419 Low back pain Occasional (29-5%)
HP:0004808 Acute myeloid leukemia Occasional (29-5%)
HP:0004820 Acute myelomonocytic leukemia Occasional (29-5%)
HP:0005528 Bone marrow hypocellularity Occasional (29-5%)
HP:0031385 Megakaryocyte nucleus hypolobulation Occasional (29-5%)
HP:0031386 Increased micromegakaryocyte count Occasional (29-5%)
HP:0100827 Lymphocytosis Occasional (29-5%)
HP:0001744 Splenomegaly Very rare (4-1%)


Phenotype(s) retrieved from case reports

    Total: 17

HPO ID Term # of case reports
HP:0001909 Leukemia 11
HP:0001876 Pancytopenia 7
HP:0011974 Myelofibrosis 7
HP:0001433 Hepatosplenomegaly 2
HP:0001744 Splenomegaly 2
HP:0002488 Acute leukemia 2
HP:0001894 Thrombocytosis 1
HP:0001903 Anemia 1
HP:0001974 Leukocytosis 1
HP:0002090 Pneumonia 1
HP:0002653 Bone pain 1
HP:0002863 Myelodysplasia 1
HP:0003072 Hypercalcemia 1
HP:0004377 Hematological neoplasm 1
HP:0004447 Poikilocytosis 1
HP:0004823 Anisopoikilocytosis 1
HP:0200036 Skin nodule 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID