| Rank (Similarity) |
PMID (PMCID) |
|
|---|---|---|
| 4 (4.0%) |
17629784 |
Management of type 2 diabetes mellitus associated with pituitary gigantism. Ali O, Banerjee S, Kelly DF, Lee PD. Pituitary. 2007;10(4):359-64. |
| Diabetes mellitus | ||
| GH1 IGF1 | ||
| Adenoma Antineoplastic Agents Combined Modality Therapy Diabetes Mellitus, Non-Insulin-Dependent Ergolines Gigantism Homo sapiens Human Growth Hormone Hypoglycemic Agents Insulin Insulin, Long-Acting Male Pituitary Neoplasms | ||
| 4 (4.0%) |
16061823 |
Pegvisomant therapy in pituitary gigantism: successful treatment in a 12-year-old girl. Rix M, Laurberg P, Hoejberg AS, Brock-Jacobsen B. Eur J Endocrinol. 2005;153(2):195-201. |
| Tall stature | ||
| GHR IGF1 | ||
| Adenoma Body Height Child Females Gigantism Growth Hormone Receptor Homo sapiens Human Growth Hormone Insulin-Like Growth Factor I Magnetic Resonance Imaging Pituitary Neoplasms | ||
| 4 (4.0%) |
15516776 |
Long-term effects of octreotide on pituitary gigantism: its analgesic action on cluster headache. Otsuka F, Mizobuchi S, Ogura T, Sato K, Yokoyama M, Makino H. Endocr J. 2004;51(5):449-52. |
| Headache | ||
| GH1 | ||
| Adenoma Adult Analgesics, Opioid Antineoplastic Agents, Hormonal Cluster Headache Gigantism Homo sapiens Male Pain Measurement Pituitary Neoplasms Self Administration | ||
| 4 (4.0%) |
11081147 |
Transsphenoidal surgery for pituitary gigantism and galactorrhea in a 3.5 year old child. Flitsch J, Ludecke DK, Stahnke N, Wiebel J, Saeger W. Pituitary. 2000;2(4):261-7. |
| Diabetes insipidus | ||
| GH1 IGF1 IGFBP3 | ||
| Child, Preschool Dopamine Agonists Females Galactorrhea Gigantism Homo sapiens Human Growth Hormone Magnetic Resonance Imaging Pituitary Neoplasms Postoperative Complications Prolactinoma | ||
| 4 (4.0%) |
10614552 |
Pituitary gigantism causing diabetic ketoacidosis. Alvi NS, Kirk JM. J Pediatr Endocrinol Metab. 1999;12(6):907-9. |
| Tall stature | ||
| GH1 | ||
| Adenoma Child Diabetic Ketoacidosis Gigantism Growth Hormone Homo sapiens Insulin Male Pituitary Neoplasms | ||
| 4 (4.0%) |
10478817 |
Myocardial infarction with Moyamoya disease and pituitary gigantism in a young female patient. Ahn YK, Jeong MH, Bom HS, Park JC, Kim JK, Chung DJ, Chung MY, Cho JG, Kang JC. Jpn Circ J. 1999;63(8):644-8. |
| Myocardial infarction | ||
| Adult Angioplasty, Balloon, Coronary Carotid Arteries Chest Pain Dyspnea Females Gigantism Homo sapiens Moyamoya Disease Myocardial Infarction Tomography, Emission-Computed, Single-Photon | ||
| 4 (4.0%) |
8550769 |
Growth hormone (GH) secretory dynamics in a case of acromegalic gigantism associated with hyperprolactinemia: nonpulsatile secretion of GH may induce elevated insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 levels. Yoshida T, Shimatsu A, Sakane N, Hizuka N, Horikawa R, Tanaka T. J Clin Endocrinol Metab. 1996;81(1):310-3. |
| Hypoglycemia | ||
| GH1 IGF1 IGFBP3 | ||
| Acromegaly Adult Gigantism Growth Hormone Homo sapiens Hyperprolactinemia Insulin-Like Growth Factor Binding Protein 3 Insulin-Like Growth Factor I Male | ||
| 4 (4.0%) |
8394228 |
Severe peripheral neuropathy and elevated plantar pressures causing foot ulceration in pituitary gigantism. Jennings AM, Robinson A, Kandler RH, Betts RP, Ryder RE, Cullen DR. Clin Endocrinol (Oxf). 1993;39(1):113-8. |
| Diabetes mellitus | ||
| Adult Foot Foot Ulcer Gigantism Homo sapiens Male Peripheral Nervous System Diseases Sweating | ||
| 4 (4.0%) |
6420141 |
A case of pituitary gigantism who had two episodes of diabetic ketoacidosis followed by complete recovery of diabetes. Kuzuya T, Matsuda A, Sakamoto Y, Yamamoto K, Saito T, Yoshida S. Endocrinol Jpn. 1983;30(3):329-34. |
| Diabetic ketoacidosis | ||
| GH1 INS | ||
| C-Peptide Diabetic Ketoacidosis Gigantism Growth Hormone Homo sapiens Hypophysectomy Insulin Male Pituitary Hormones, Anterior | ||
| 4 (4.0%) |
1593354 |
Pituitary gigantism caused by growth hormone excess from infancy. Gelber SJ, Heffez DS, Donohoue PA. J Pediatr. 1992;120(6):931-4. |
| Visual loss | ||
| GH1 PRL | ||
| Adenoma Child, Preschool Gigantism Growth Hormone Homo sapiens Male Optic Atrophy Pituitary Neoplasms Vision Disorders |
Total: 20
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0000098 | Tall stature | Very frequent (99-80%) |
| HP:0000280 | Coarse facial features | Very frequent (99-80%) |
| HP:0000303 | Mandibular prognathia | Very frequent (99-80%) |
| HP:0000845 | Growth hormone excess | Very frequent (99-80%) |
| HP:0000975 | Hyperhidrosis | Very frequent (99-80%) |
| HP:0001176 | Large hands | Very frequent (99-80%) |
| HP:0001639 | Hypertrophic cardiomyopathy | Very frequent (99-80%) |
| HP:0001712 | Left ventricular hypertrophy | Very frequent (99-80%) |
| HP:0001833 | Long foot | Very frequent (99-80%) |
| HP:0002007 | Frontal bossing | Very frequent (99-80%) |
| HP:0005616 | Accelerated skeletal maturation | Very frequent (99-80%) |
| HP:0005978 | Type II diabetes mellitus | Very frequent (99-80%) |
| HP:0011407 | Proportionate tall stature | Very frequent (99-80%) |
| HP:0011760 | Pituitary growth hormone cell adenoma | Very frequent (99-80%) |
| HP:0012411 | Premature pubarche | Very frequent (99-80%) |
| HP:0030269 | Increased serum insulin-like growth factor 1 | Very frequent (99-80%) |
| HP:0000141 | Amenorrhea | Frequent (79-30%) |
| HP:0000870 | Prolactin excess | Frequent (79-30%) |
| HP:0006767 | Pituitary prolactin cell adenoma | Frequent (79-30%) |
| HP:0100829 | Galactorrhea | Occasional (29-5%) |
Total: 9
| HPO ID | Term | # of case reports |
|---|---|---|
| HP:0001953 | Diabetic ketoacidosis | 2 |
| HP:0000252 | Microcephaly | 1 |
| HP:0000819 | Diabetes mellitus | 1 |
| HP:0001658 | Myocardial infarction | 1 |
| HP:0002315 | Headache | 1 |
| HP:0009830 | Peripheral neuropathy | 1 |
| HP:0012199 | Cluster headache | 1 |
| HP:0030799 | Scaphocephaly | 1 |
| HP:0100829 | Galactorrhea | 1 |
Total: 0
| Gene Symbol | Gene Name | Entrez Gene ID |
|---|