Babesiosis

Babesiosis is an infectious disease caused by protozoa of the genus <i>Babesia</i> and characterized by a febrile illness and hemolytic anemia but with manifestations ranging from an asymptomatic infection to a fulminating illness that can result in death.



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Narrow down the case reports



Total: 149 (papers)

   


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
1
(60.6%)		 16462298
 Neonatal babesiosis: case report and review of the literature.
Fox LM, Wingerter S, Ahmed A, Arnold A, Chou J, Rhein L, Levy O.
Pediatr Infect Dis J. 2006;25(2):169-73.
Jaundice Hepatosplenomegaly Anemia Conjugated hyperbilirubinemia
Adult Animals Babesia Babesiosis Females Homo sapiens Infant, Newborn Infant, Premature, Diseases Male Preterm Infant Transfusion Reaction
2
(54.2%)		 30245087
 Clinical, morphological, and molecular characterization of an undetermined Babesia species in a maned wolf (Chrysocyon brachyurus).
Wasserkrug Naor A, Lindemann DM, Schreeg ME, Marr HS, Birkenheuer AJ, Carpenter JW, Ryseff JK.
Ticks Tick Borne Dis. 2019;10(1):124-126.
Jaundice Anemia Azotemia
Animals Animals, Zoo Anti-Infective Agents Babesia Babesiosis Females
3
(53.6%)		 28202022
(5310009)
 Hematologic manifestations of babesiosis.
Akel T, Mobarakai N.
Ann Clin Microbiol Antimicrob. 2017;16(1):6.
Hemolytic anemia Fever Splenic rupture
Anemia, Hemolytic Babesia Babesiosis Bone Marrow Erythrocytes Females Fever Homo sapiens Immunocompetence Neutropenia New York City Thrombocytopenia
3
(53.6%)		 18270666
 [Babesiosis in an immunocompromised German patient].
Haselbarth K, Kurz M, Hunfeld KP, Krieger G.
Med Klin (Munich). 2008;103(2):104-7.
Asplenia Hemolytic anemia Hemoglobinuria
Anti-Bacterial Agents Antibodies, Monoclonal, Murine-Derived Antimalarials Antineoplastic Agents B-Cell Lymphomas Babesiosis Combination Drug Therapy Homo sapiens Immunologic Deficiency Syndromes Male Middle Aged Monoclonal Antibodies Opportunistic Infections Splenectomy
5
(51.9%)		 7200325
 Ocular findings in human babesiosis (Nantucket fever).
Ortiz JM, Eagle RC Jr.
Am J Ophthalmol. 1982;93(3):307-11.
Hemolytic anemia Fever Lymphadenopathy Hepatitis
Adult Animals Babesiosis Collagen Diseases Differential Diagnosis Females Homo sapiens Retinal Diseases Splenectomy
6
(50.0%)		 25895861
 The anemic and thrombocytopenic febrile neonate.
Surra ND, Jesus JE.
J Emerg Med. 2015;48(6):675-8.
Splenomegaly Anemia
Anemia Babesiosis Fever Homo sapiens Infant, Newborn Male Splenomegaly Thrombocytopenia
7
(48.9%)		 9677835
 [Imported hepatozoonosis in the dog: 3 cases].
Arnold P, Deplazes P, Muller A, Kupper J, Lutz H, Glaus T.
Schweiz Arch Tierheilkd. 1998;140(7):287-93.
Anemia Fever Vomiting Lymphadenopathy
Animals Canis familiaris Coccidiosis Dog Diseases Ehrlichiosis Females Leishmaniasis Male
8
(47.8%)		 9590496
 Therapeutic apheresis for babesiosis.
Evenson DA, Perry E, Kloster B, Hurley R, Stroncek DF.
J Clin Apher. 1998;13(1):32-6.
Pancreatitis Hemolytic anemia Fever
Adult Anti-Bacterial Agents Babesiosis Homo sapiens Immunocompetence Immunocompromised Host Male Middle Aged Plasmapheresis Red Blood Cell Transfusion
9
(47.4%)		 29567936
(5878539)
 Splenic Rupture as the First Manifestation of Babesia Microti Infection: Report of a Case and Review of Literature.
Dumic I, Patel J, Hart M, Niendorf ER, Martin S, Ramanan P.
Am J Case Rep. 2018;19:335-341.
Hepatic failure Hemolytic anemia Splenic rupture
Animals Anti-Bacterial Agents Babesiosis Females Homo sapiens Splenectomy Splenic Rupture
9
(47.4%)		 26123434
 Atraumatic splenic rupture from Babesia: A disease of the otherwise healthy patient.
Farber FR, Muehlenbachs A, Robey TE.
Ticks Tick Borne Dis. 2015;6(5):649-52.
Anemia Splenic rupture
Animals Babesia Babesiosis Hematoma Hemoperitoneum Homo sapiens Middle Aged Rupture, Spontaneous Splenectomy Splenic Diseases
        

Phenotype(s) retrieved from Orphanet

    Total: 31

HPO ID Term Frequency
HP:0001878 Hemolytic anemia Very frequent (99-80%)
HP:0001945 Fever Very frequent (99-80%)
HP:0002315 Headache Very frequent (99-80%)
HP:0000952 Jaundice Frequent (79-30%)
HP:0000975 Hyperhidrosis Frequent (79-30%)
HP:0001744 Splenomegaly Frequent (79-30%)
HP:0001873 Thrombocytopenia Frequent (79-30%)
HP:0001882 Leukopenia Frequent (79-30%)
HP:0002240 Hepatomegaly Frequent (79-30%)
HP:0002719 Recurrent infections Frequent (79-30%)
HP:0002829 Arthralgia Frequent (79-30%)
HP:0003326 Myalgia Frequent (79-30%)
HP:0012378 Fatigue Frequent (79-30%)
HP:0012735 Cough Frequent (79-30%)
HP:0000083 Renal insufficiency Occasional (29-5%)
HP:0000613 Photophobia Occasional (29-5%)
HP:0000716 Depressivity Occasional (29-5%)
HP:0001259 Coma Occasional (29-5%)
HP:0001289 Confusion Occasional (29-5%)
HP:0001376 Limitation of joint mobility Occasional (29-5%)
HP:0001399 Hepatic failure Occasional (29-5%)
HP:0001635 Congestive heart failure Occasional (29-5%)
HP:0001658 Myocardial infarction Occasional (29-5%)
HP:0001864 Clinodactyly of the 5th toe Occasional (29-5%)
HP:0002017 Nausea and vomiting Occasional (29-5%)
HP:0002039 Anorexia Occasional (29-5%)
HP:0002093 Respiratory insufficiency Occasional (29-5%)
HP:0004936 Venous thrombosis Occasional (29-5%)
HP:0005521 Disseminated intravascular coagulation Occasional (29-5%)
HP:0100724 Hypercoagulability Occasional (29-5%)
HP:0100776 Recurrent pharyngitis Occasional (29-5%)


Phenotype(s) retrieved from case reports

    Total: 53

HPO ID Term # of case reports
HP:0001945 Fever 17
HP:0001873 Thrombocytopenia 9
HP:0001878 Hemolytic anemia 9
HP:0012223 Splenic rupture 6
HP:0001876 Pancytopenia 4
HP:0001903 Anemia 4
HP:0002098 Respiratory distress 4
HP:0100598 Pulmonary edema 3
HP:0001746 Asplenia 2
HP:0001888 Lymphopenia 2
HP:0012378 Fatigue 2
HP:0025143 Chills 2
HP:0000083 Renal insufficiency 1
HP:0000618 Blindness 1
HP:0000952 Jaundice 1
HP:0000989 Pruritus 1
HP:0001251 Ataxia 1
HP:0001289 Confusion 1
HP:0001370 Rheumatoid arthritis 1
HP:0001638 Cardiomyopathy 1
HP:0001640 Cardiomegaly 1
HP:0001744 Splenomegaly 1
HP:0001909 Leukemia 1
HP:0001919 Acute kidney injury 1
HP:0001923 Reticulocytosis 1
HP:0001955 Unexplained fevers 1
HP:0001974 Leukocytosis 1
HP:0002157 Azotemia 1
HP:0002202 Pleural effusion 1
HP:0002315 Headache 1
HP:0002716 Lymphadenopathy 1
HP:0002721 Immunodeficiency 1
HP:0002829 Arthralgia 1
HP:0002904 Hyperbilirubinemia 1
HP:0002960 Autoimmunity 1
HP:0003201 Rhabdomyolysis 1
HP:0003470 Paralysis 1
HP:0003641 Hemoglobinuria 1
HP:0005575 Hemolytic-uremic syndrome 1
HP:0006562 Viral hepatitis 1
HP:0006702 Coronary artery dissection 1
HP:0007866 Retinal infarction 1
HP:0010783 Erythema 1
HP:0011675 Arrhythmia 1
HP:0012115 Hepatitis 1
HP:0012156 Hemophagocytosis 1
HP:0012486 Myelitis 1
HP:0025142 Constitutional symptom 1
HP:0025435 Increased lactate dehydrogenase activity 1
HP:0031003 Polyneuritis 1
HP:0031035 Chronic infection 1
HP:0031273 Shock 1
HP:0100806 Sepsis 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID