Babesiosis

Babesiosis is an infectious disease caused by protozoa of the genus <i>Babesia</i> and characterized by a febrile illness and hemolytic anemia but with manifestations ranging from an asymptomatic infection to a fulminating illness that can result in death.



Input patient's signs and symptoms


Narrow down the case reports



Total: 149 (papers)

   


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
11
(45.3%)		 27051577
(4802672)
 Atypical challenging and first case report of babesiosis in Ecuador.
Al Zoubi M, Kwak T, Patel J, Kulkarni M, Kallal CA.
IDCases. 2016;4:15-7.
Splenomegaly Fever Leukocytosis
HP
12
(44.2%)		 21453973
 Recurrent fever of unknown origin (FUO): aseptic meningitis, hepatosplenomegaly, pericarditis and a double quotidian fever due to juvenile rheumatoid arthritis (JRA).
Cunha BA, Hage JE, Nouri Y.
Heart Lung. 2012;41(2):177-80.
Hepatosplenomegaly Leukemia Fever
Aseptic Meningitis Body Temperature Differential Diagnosis Fever of Unknown Origin Hepatomegaly Homo sapiens Magnetic Resonance Imaging Male Pericarditis Splenomegaly Young Adult
13
(43.7%)		 27755775
 Spurious reticulocyte profiles in a dog with babesiosis.
Piane L, Theron ML, Aumann M, Trumel C.
Vet Clin Pathol. 2016;45(4):594-597.
Anemia Anorexia Hyperbilirubinemia
Animals Babesia Babesiosis Blood Cell Count Canis familiaris Dog Diseases Erythrocytes Females Reticulocytes
13
(43.7%)		 24517274
(3989376)
 Persistent babesiosis in a Rhesus macaque (Macaca mulatta) infected with a simian-human immunodeficiency virus.
Liu DX, Gill A, Holman PJ, Didier PJ, Blanchard JL, Veazey RS, Lackner AA.
J Med Primatol. 2014;43(3):206-8.
Anemia Fever Anorexia
Animals Animals, Laboratory Babesiosis DNA, Protozoan Females HIV-1 Macaca mulatta Molecular Sequence Data Monkey Diseases Polymerase Chain Reaction RNA, Ribosomal, 18S Sequence Analysis, DNA Simian Acquired Immunodeficiency Syndrome
15
(43.3%)		 21862413
 Babesiosis: an emerging infectious disease that can affect those who travel to the northeastern United States.
Chiang E, Haller N.
Travel Med Infect Dis. 2011;9(5):238-42.
Jaundice Thrombocytopenia Fever
Babesiosis Communicable Diseases, Emerging Differential Diagnosis Erythrocytes Homo sapiens Male Middle Aged New England
16
(42.9%)		 23676299
(3942935)
 Generalized alopecia with vasculitis-like changes in a dog with babesiosis.
Tasaki Y, Miura N, Iyori K, Nishifuji K, Endo Y, Momoi Y.
J Vet Med Sci. 2013;75(10):1367-9.
Anemia Erythema
Alopecia Animals Antiprotozoal Agents Babesia Babesiosis Biopsy Canis familiaris Dog Diseases Females Histocytochemistry Vasculitis, Leukocytoclastic, Cutaneous
17
(41.8%)		 2051446
 An outbreak of babesiosis in imported sable antelope (Hippotragus niger).
McInnes EF, Stewart CG, Penzhorn BL, Meltzer DG.
J S Afr Vet Assoc. 1991;62(1):30-2.
Petechiae Splenomegaly
Animals Babesia Babesiosis Disease Outbreaks South Africa
18
(41.4%)		 31016091
 Triple Tick Attack.
Kumar M, Sharma A, Grover P.
Cureus. 2019;11(2):e4064.
Pallor Hemolytic anemia Peripheral edema
19
(37.8%)		 24596410
 Pancytopenia in Lyme disease.
Mehrzad R, Bravoco J.
BMJ Case Rep. 2014;2014:.
Pancytopenia Fever Hepatitis
Differential Diagnosis Homo sapiens Lyme Disease Male Middle Aged Pancytopenia
20
(37.6%)		 29355731
 Human babesiosis in Southeast China: A case report.
Huang S, Zhang L, Yao L, Li J, Chen H, Ni Q, Pan C, Jin L.
Int J Infect Dis. 2018;68:36-38.
Thrombocytopenia Neutropenia Hemolytic anemia Fever
CRP
Anemia, Hemolytic Anti-Bacterial Agents Babesiosis China Females Fever Homo sapiens Middle Aged Neutropenia Thrombocytopenia
        

Phenotype(s) retrieved from Orphanet

    Total: 31

HPO ID Term Frequency
HP:0001878 Hemolytic anemia Very frequent (99-80%)
HP:0001945 Fever Very frequent (99-80%)
HP:0002315 Headache Very frequent (99-80%)
HP:0000952 Jaundice Frequent (79-30%)
HP:0000975 Hyperhidrosis Frequent (79-30%)
HP:0001744 Splenomegaly Frequent (79-30%)
HP:0001873 Thrombocytopenia Frequent (79-30%)
HP:0001882 Leukopenia Frequent (79-30%)
HP:0002240 Hepatomegaly Frequent (79-30%)
HP:0002719 Recurrent infections Frequent (79-30%)
HP:0002829 Arthralgia Frequent (79-30%)
HP:0003326 Myalgia Frequent (79-30%)
HP:0012378 Fatigue Frequent (79-30%)
HP:0012735 Cough Frequent (79-30%)
HP:0000083 Renal insufficiency Occasional (29-5%)
HP:0000613 Photophobia Occasional (29-5%)
HP:0000716 Depressivity Occasional (29-5%)
HP:0001259 Coma Occasional (29-5%)
HP:0001289 Confusion Occasional (29-5%)
HP:0001376 Limitation of joint mobility Occasional (29-5%)
HP:0001399 Hepatic failure Occasional (29-5%)
HP:0001635 Congestive heart failure Occasional (29-5%)
HP:0001658 Myocardial infarction Occasional (29-5%)
HP:0001864 Clinodactyly of the 5th toe Occasional (29-5%)
HP:0002017 Nausea and vomiting Occasional (29-5%)
HP:0002039 Anorexia Occasional (29-5%)
HP:0002093 Respiratory insufficiency Occasional (29-5%)
HP:0004936 Venous thrombosis Occasional (29-5%)
HP:0005521 Disseminated intravascular coagulation Occasional (29-5%)
HP:0100724 Hypercoagulability Occasional (29-5%)
HP:0100776 Recurrent pharyngitis Occasional (29-5%)


Phenotype(s) retrieved from case reports

    Total: 53

HPO ID Term # of case reports
HP:0001945 Fever 17
HP:0001873 Thrombocytopenia 9
HP:0001878 Hemolytic anemia 9
HP:0012223 Splenic rupture 6
HP:0001876 Pancytopenia 4
HP:0001903 Anemia 4
HP:0002098 Respiratory distress 4
HP:0100598 Pulmonary edema 3
HP:0001746 Asplenia 2
HP:0001888 Lymphopenia 2
HP:0012378 Fatigue 2
HP:0025143 Chills 2
HP:0000083 Renal insufficiency 1
HP:0000618 Blindness 1
HP:0000952 Jaundice 1
HP:0000989 Pruritus 1
HP:0001251 Ataxia 1
HP:0001289 Confusion 1
HP:0001370 Rheumatoid arthritis 1
HP:0001638 Cardiomyopathy 1
HP:0001640 Cardiomegaly 1
HP:0001744 Splenomegaly 1
HP:0001909 Leukemia 1
HP:0001919 Acute kidney injury 1
HP:0001923 Reticulocytosis 1
HP:0001955 Unexplained fevers 1
HP:0001974 Leukocytosis 1
HP:0002157 Azotemia 1
HP:0002202 Pleural effusion 1
HP:0002315 Headache 1
HP:0002716 Lymphadenopathy 1
HP:0002721 Immunodeficiency 1
HP:0002829 Arthralgia 1
HP:0002904 Hyperbilirubinemia 1
HP:0002960 Autoimmunity 1
HP:0003201 Rhabdomyolysis 1
HP:0003470 Paralysis 1
HP:0003641 Hemoglobinuria 1
HP:0005575 Hemolytic-uremic syndrome 1
HP:0006562 Viral hepatitis 1
HP:0006702 Coronary artery dissection 1
HP:0007866 Retinal infarction 1
HP:0010783 Erythema 1
HP:0011675 Arrhythmia 1
HP:0012115 Hepatitis 1
HP:0012156 Hemophagocytosis 1
HP:0012486 Myelitis 1
HP:0025142 Constitutional symptom 1
HP:0025435 Increased lactate dehydrogenase activity 1
HP:0031003 Polyneuritis 1
HP:0031035 Chronic infection 1
HP:0031273 Shock 1
HP:0100806 Sepsis 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID