Babesiosis

Babesiosis is an infectious disease caused by protozoa of the genus <i>Babesia</i> and characterized by a febrile illness and hemolytic anemia but with manifestations ranging from an asymptomatic infection to a fulminating illness that can result in death.



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Narrow down the case reports



Total: 149 (papers)

   


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
20
(37.6%)		 28636757
 Babesiosis: An unusual cause of sepsis after kidney transplantation and review of the literature.
Ather I, Pourafshar N, Schain D, Gupte A, Casey MJ.
Transpl Infect Dis. 2017;19(5):.
Hemolytic anemia Fever Sepsis
Babesiosis Females Homo sapiens Kidney Transplantation Sepsis
20
(37.6%)		 18992633
 Fever of unknown origin (FUO) due to babesiosis in a immunocompetent host.
Cunha BA, Cohen YZ, McDermott B.
Heart Lung. 2008;37(6):481-4.
Thrombocytopenia Hemolytic anemia Lymphopenia Fever
Animals Anti-Bacterial Agents Babesia Babesiosis Combination Drug Therapy Fever of Unknown Origin Follow-Up Studies Health Risk Assessment Homo sapiens Immunocompetence Male Radiography, Thoracic Rare Diseases Severity of Illness Index
20
(37.6%)		 8781622
 Babesiosis and hemophagocytic syndrome in an asplenic renal transplant recipient.
Slovut DP, Benedetti E, Matas AJ.
Transplantation. 1996;62(4):537-9.
Pancytopenia Anemia Fever Hemophagocytosis
Babesiosis Bone Marrow Histiocytosis, Non-Langerhans-Cell Homo sapiens Immunocompromised Host Kidney Transplantation Male Middle Aged Splenectomy Tick-Borne Diseases
20
(37.6%)		 8722936
 Babesiosis in patients with AIDS: a chronic infection presenting as fever of unknown origin.
Falagas ME, Klempner MS.
Clin Infect Dis. 1996;22(5):809-12.
Anemia Fever Chronic infection
AIDS-Related Opportunistic Infections Adult Antimalarials Babesiosis Combination Drug Therapy Fever of Unknown Origin Homo sapiens Male Parasitemia
25
(37.6%)		 29277955
 Tick-borne illness after transplantation: Case and review.
Mascarenhas TR, Silibovsky RS, Singh P, Belden KA.
Transpl Infect Dis. 2018;20(2):e12830.
Lethargy Anemia Fever Hypotension
Anti-Infective Agents Antibodies, Protozoan Babesiosis Homo sapiens Kidney Transplantation Male
26
(37.5%)		 22448525
 Severe anemia caused by babesiosis in a maned wolf (Chrysocyon brachyurus).
Phair KA, Carpenter JW, Smee N, Myers CB, Pohlman LM.
J Zoo Wildl Med. 2012;43(1):162-7.
Blindness Anemia Vomiting
Anemia Animals Antiprotozoal Agents Babesiosis Blood Transfusion Females Male
26
(37.5%)		 11020989
 [First documentation of transfusion-associated babesiosis in Japan].
Matsui T, Inoue R, Kajimoto K, Tamekane A, Okamura A, Katayama Y, Shimoyama M, Chihara K, Saito-Ito A, Tsuji M.
Rinsho Ketsueki. 2000;41(8):628-34.
Hemolytic anemia Peptic ulcer
Adult Animals Babesiosis Homo sapiens Japan Male Peptic Ulcer Hemorrhage Transfusion Reaction
28
(36.5%)		 21683324
 Transfusion-transmitted babesiosis in an immunocompromised patient: a case report and review.
Wudhikarn K, Perry EH, Kemperman M, Jensen KA, Kline SE.
Am J Med. 2011;124(9):800-5.
Asplenia Leukemia
Anti-Bacterial Agents Antimalarials Antineoplastic Agents Babesiosis Chronic Lymphocytic Leukemia Combination Drug Therapy Females Homo sapiens Immunocompromised Host Middle Aged Opportunistic Infections Respiratory Insufficiency Splenectomy Transfusion Reaction
29
(34.0%)		 19622029
 Babesiosis in the immediate postoperative period after splenectomy for trauma.
Semel ME, Tavakkolizadeh A, Gates JD.
Surg Infect (Larchmt). 2009;10(6):553-6.
Splenomegaly Fever
Animals Anti-Bacterial Agents Antiprotozoal Agents Babesiosis Females Homo sapiens Middle Aged Splenectomy Surgical Wound Infection Wounds and Injuries
30
(33.4%)		 28405337
(5385069)
 Autoimmune hemolytic anemia associated with babesiosis.
Narurkar R, Mamorska-Dyga A, Nelson JC, Liu D.
Biomark Res. 2017;5:14.
Thrombocytopenia Anemia Hyponatremia
        

Phenotype(s) retrieved from Orphanet

    Total: 31

HPO ID Term Frequency
HP:0001878 Hemolytic anemia Very frequent (99-80%)
HP:0001945 Fever Very frequent (99-80%)
HP:0002315 Headache Very frequent (99-80%)
HP:0000952 Jaundice Frequent (79-30%)
HP:0000975 Hyperhidrosis Frequent (79-30%)
HP:0001744 Splenomegaly Frequent (79-30%)
HP:0001873 Thrombocytopenia Frequent (79-30%)
HP:0001882 Leukopenia Frequent (79-30%)
HP:0002240 Hepatomegaly Frequent (79-30%)
HP:0002719 Recurrent infections Frequent (79-30%)
HP:0002829 Arthralgia Frequent (79-30%)
HP:0003326 Myalgia Frequent (79-30%)
HP:0012378 Fatigue Frequent (79-30%)
HP:0012735 Cough Frequent (79-30%)
HP:0000083 Renal insufficiency Occasional (29-5%)
HP:0000613 Photophobia Occasional (29-5%)
HP:0000716 Depressivity Occasional (29-5%)
HP:0001259 Coma Occasional (29-5%)
HP:0001289 Confusion Occasional (29-5%)
HP:0001376 Limitation of joint mobility Occasional (29-5%)
HP:0001399 Hepatic failure Occasional (29-5%)
HP:0001635 Congestive heart failure Occasional (29-5%)
HP:0001658 Myocardial infarction Occasional (29-5%)
HP:0001864 Clinodactyly of the 5th toe Occasional (29-5%)
HP:0002017 Nausea and vomiting Occasional (29-5%)
HP:0002039 Anorexia Occasional (29-5%)
HP:0002093 Respiratory insufficiency Occasional (29-5%)
HP:0004936 Venous thrombosis Occasional (29-5%)
HP:0005521 Disseminated intravascular coagulation Occasional (29-5%)
HP:0100724 Hypercoagulability Occasional (29-5%)
HP:0100776 Recurrent pharyngitis Occasional (29-5%)


Phenotype(s) retrieved from case reports

    Total: 53

HPO ID Term # of case reports
HP:0001945 Fever 17
HP:0001873 Thrombocytopenia 9
HP:0001878 Hemolytic anemia 9
HP:0012223 Splenic rupture 6
HP:0001876 Pancytopenia 4
HP:0001903 Anemia 4
HP:0002098 Respiratory distress 4
HP:0100598 Pulmonary edema 3
HP:0001746 Asplenia 2
HP:0001888 Lymphopenia 2
HP:0012378 Fatigue 2
HP:0025143 Chills 2
HP:0000083 Renal insufficiency 1
HP:0000618 Blindness 1
HP:0000952 Jaundice 1
HP:0000989 Pruritus 1
HP:0001251 Ataxia 1
HP:0001289 Confusion 1
HP:0001370 Rheumatoid arthritis 1
HP:0001638 Cardiomyopathy 1
HP:0001640 Cardiomegaly 1
HP:0001744 Splenomegaly 1
HP:0001909 Leukemia 1
HP:0001919 Acute kidney injury 1
HP:0001923 Reticulocytosis 1
HP:0001955 Unexplained fevers 1
HP:0001974 Leukocytosis 1
HP:0002157 Azotemia 1
HP:0002202 Pleural effusion 1
HP:0002315 Headache 1
HP:0002716 Lymphadenopathy 1
HP:0002721 Immunodeficiency 1
HP:0002829 Arthralgia 1
HP:0002904 Hyperbilirubinemia 1
HP:0002960 Autoimmunity 1
HP:0003201 Rhabdomyolysis 1
HP:0003470 Paralysis 1
HP:0003641 Hemoglobinuria 1
HP:0005575 Hemolytic-uremic syndrome 1
HP:0006562 Viral hepatitis 1
HP:0006702 Coronary artery dissection 1
HP:0007866 Retinal infarction 1
HP:0010783 Erythema 1
HP:0011675 Arrhythmia 1
HP:0012115 Hepatitis 1
HP:0012156 Hemophagocytosis 1
HP:0012486 Myelitis 1
HP:0025142 Constitutional symptom 1
HP:0025435 Increased lactate dehydrogenase activity 1
HP:0031003 Polyneuritis 1
HP:0031035 Chronic infection 1
HP:0031273 Shock 1
HP:0100806 Sepsis 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID