Chronic beryllium disease

Chronic beryllium disease (CBD) is a granulomatous, interstitial lung disease that occurs in individuals who develop beryllium sensitization (BeS), a cell-mediated immune response to environmental and occupational beryllium exposure. BeS precedes the lung disease that may present with chronic dry cough, fatigue, weight loss, chest pain, and increasing dyspnea.



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Total: 34 (papers)

   


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
2
(4.0%)		 2818233
 [Pulmonary berylliosis].
Dmitruk IM, Berel'kovskii VL, Nepomniashchaia EM, Markova TI, Popova LP.
Arkh Patol. 1989;51(8):71-4.
Granuloma
Adult Berylliosis Bronchi Females Homo sapiens Lung Pregnancy
2
(4.0%)		 2629665
 [Chronic berylliosis of the lungs].
Blokhin AV.
Arkh Patol. 1989;51(12):52-5.
Bronchitis
Berylliosis Giant Cell Granuloma Granuloma, Foreign-Body Histocytochemistry Homo sapiens Lung Male Sclerosis
2
(4.0%)		 2407626
 [Neurosarcoidosis. Comparative analysis of the clinical profile based on 537 cases from the world literature up to 1963 and from 1976-1988].
Mende D, Suchenwirth RM.
Fortschr Neurol Psychiatr. 1990;58(1):7-18.
Nystagmus
ACE
Adult Brain Diseases Females Homo sapiens Sarcoidosis Spinal Cord Diseases
2
(4.0%)		 1792645
 Endoscopic bougie and balloon dilatation of multiple bronchial stenoses: 10 year follow up.
Ball JB, Delaney JC, Evans CC, Donnelly RJ, Hind CR.
Thorax. 1991;46(12):933-5.
Vascular dilatation
Adult Bronchial Diseases Bronchoscopy Catheterization Females Homo sapiens Lung Diseases, Obstructive Male Middle Aged Respiratory Function Tests Stenosis
        

Phenotype(s) retrieved from Orphanet

    Total: 0

HPO ID Term Frequency


Phenotype(s) retrieved from case reports

    Total: 9

HPO ID Term # of case reports
HP:0032252 Granuloma 7
HP:0002955 Granulomatosis 2
HP:0003072 Hypercalcemia 2
HP:0002090 Pneumonia 1
HP:0002110 Bronchiectasis 1
HP:0002617 Dilatation 1
HP:0002789 Tachypnea 1
HP:0012819 Myocarditis 1
HP:0030250 Pulmonary granulomatosis 1


Causative gene(s) retrieved from Orphanet

    Total: 1

Gene Symbol Gene Name Entrez Gene ID
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 3115