Aspergillosis

A rare infectious disease caused by inhalation of the opportunistic fungus <i>aspergillus</i> that can lead to the following manifestations: allergic bronchopulmonary aspergillosis (ABPA), aspergilloma, chronic necrotizing pulmonary aspergillosis (CNPA), and invasive aspergillosis (IA). Aspergilloma occurs in patients with cavitary lung disease and results in a fungal mass with variable clinical presentations from asymptomatic to life-threatening (massive hemoptysis). CNPA manifests as subacute pneumonia in patients with underlying disease. IA is disseminated aspergillosis that eventually invades other organs. Cutaneous aspergillosis is usually the dermatological manifestation of IA that manifests as erythematous-to-violaceous plaques or papules, often characterized by a central necrotic ulcer or eschar.



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Narrow down the case reports



Total: 1886 (papers)

  


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)
PMID
(PMCID)
18
(38.2%)
7565443
A case of acute lymphoblastic leukemia accompanied with the production of parathyroid hormone-related protein.
Harutsumi M, Akazai A, Kitamura T, Manki A, Tanaka H, Oda M, Seino Y.
Miner Electrolyte Metab. 1995;21(1-3):171-6.
Petechiae Fever
Antineoplastic Combined Chemotherapy Protocols Child Homo sapiens Hypercalcemia Male Neoplasm Proteins Precursor Cell Lymphoblastic Leukemia Lymphoma Protein Biosynthesis Remission Induction
22
(38.0%)
24787480
Very prolonged liposomal amphotericin B use leading to a lysosomal storage disease.
Michot JM, Gubavu C, Fourn E, Maigne G, Teicher E, Angoulvant A, Blanche S, Lortholary O, Coilly A, Duclos-Vallee JC, Sebagh M, Guettier C, Aumont C, Delfraissy JF, Lambotte O.
Int J Antimicrob Agents. 2014;43(6):566-9.
Hepatosplenomegaly Pancytopenia
Adult Antifungal Agents Biopsy Histocytochemistry Homo sapiens Liver Lysosomal Storage Diseases Male Neuroaspergillosis
23
(37.8%)
27495762
(5118135)
Graft Versus Host Disease After Liver Transplantation in Adults: A Case series, Review of Literature, and an Approach to Management.
Murali AR, Chandra S, Stewart Z, Blazar BR, Farooq U, Ince MN, Dunkelberg J.
Transplantation. 2016;100(12):2661-2670.
Pancytopenia Hepatitis Bacteremia
CD2 IL2 TNF
Adult Complications of Diabetes Mellitus Databases, Factual Females Graft-vs-Host Disease Homo sapiens Iowa Male Middle Aged United States Universities Young Adult
23
(37.8%)
14672045
[Agranulocytosis due to anti-tuberculosis drugs including isoniazid (INH) and rifampicin (RFP)--a report of four cases and review of the literature].
Shishido Y, Nagayama N, Masuda K, Baba M, Tamura A, Nagai H, Akagawa S, Kawabe Y, Machida K, Kurashima A, Komatsu H, Yotsumoto H.
Kekkaku. 2003;78(11):683-9.
Gingival bleeding Fever Hepatitis
CSF3 GPT MARCH11 SLC17A5
Agranulocytosis Antitubercular Agents Females Homo sapiens Male Middle Aged Tuberculosis, Pulmonary
25
(37.6%)
25412755
(4275757)
Suppurative thyroiditis due to aspergillosis: a case report.
Marui S, de Lima Pereira AC, de Araujo Maia RM, Borba EF.
J Med Case Rep. 2014;8:379.
Lymphopenia Anemia Fever
CRP
Antifungal Agents Aspergillosis Fatal Outcome Homo sapiens Immunocompromised Host Lupus Erythematosus, Systemic Male Thyroiditis, Suppurative Young Adult
25
(37.6%)
18041706
Pure white cell aplasia in a dog.
Weiss DJ, Henson M.
Vet Clin Pathol. 2007;36(4):373-5.
Lethargy Neutropenia Hemolytic anemia Fever
Animals Canis familiaris Dog Diseases Immunosuppressive Agents Leukopenia
25
(37.6%)
11193440
[An autopsy case of pulmonary mucormycosis with fatal hemoptysis from a rupture of the thoracic descending aorta during remission from acute myelocytic leukemia].
Izumi N, Kumagai H, Shindo T.
Rinsho Ketsueki. 2000;41(11):1201-7.
Thrombocytopenia Neutropenia Anemia Fever
Aortic Aneurysm, Thoracic Aortic Rupture Females Hemoptysis Homo sapiens Leukemia, Myelocytic, Acute Lung Diseases, Fungal Mucormycosis Remission Induction
25
(37.6%)
1402119
[A case of tracho-bronchial aspergillosis complicated with acute myeloblastic leukemia].
Saburi Y, Tashiro T, Ishii T, Miyazaki S, Masuda M, Mieno T, Moriuchi A, Kikuchi H, Nasu M.
Kansenshogaku Zasshi. 1992;66(8):1120-4.
Thrombocytopenia Leukopenia Anemia Fever
Aspergillosis Bronchial Diseases Homo sapiens Leukemia, Myelocytic, Acute Male Middle Aged Tracheal Diseases
29
(37.5%)
9787330
Fatal autoimmune hemolytic anemia in a child due to warm-reactive immunoglobulin M antibody.
Friedmann AM, King KE, Shirey RS, Resar LM, Casella JF.
J Pediatr Hematol Oncol. 1998;20(5):502-5.
Hepatic failure Anemia
Adrenal Cortex Hormones Adult Autoantibodies Blood Transfusion Child Fatal Outcome Females Homo sapiens Immunoglobulin M Immunosuppressive Agents Syndrome
30
(34.8%)
29193804
Primary cutaneous aspergillosis, mimicking malignancy, a rare presentation in an immunocompetent patient.
Chaturvedi R, Kolhe A, Pardeshi K, Naik L, Wanjare S.
Diagn Cytopathol. 2018;46(5):434-437.
Edema Eosinophilia Skin ulcer
Aspergillosis Dermatomycoses Differential Diagnosis Females Homo sapiens Skin Neoplasms
        

Phenotype(s) retrieved from Orphanet

    Total: 0

HPO ID Term Frequency


Phenotype(s) retrieved from case reports

    Total: 251

HPO ID Term # of case reports
HP:0002090 Pneumonia 74
HP:0001875 Neutropenia 53
HP:0025615 Abscess 47
HP:0001909 Leukemia 41
HP:0031690 Opportunistic infection 40
HP:0000246 Sinusitis 32
HP:0002721 Immunodeficiency 32
HP:0001945 Fever 27
HP:0002488 Acute leukemia 24
HP:0002105 Hemoptysis 23
HP:0002754 Osteomyelitis 21
HP:0032252 Granuloma 21
HP:0100806 Sepsis 20
HP:0030731 Carcinoma 19
HP:0002107 Pneumothorax 18
HP:0020101 Invasive fungal infection 18
HP:0002099 Asthma 17
HP:0100584 Endocarditis 17
HP:0001287 Meningitis 16
HP:0002955 Granulomatosis 16
HP:0000819 Diabetes mellitus 14
HP:0002878 Respiratory failure 14
HP:0002098 Respiratory distress 13
HP:0030049 Brain abscess 13
HP:0001701 Pericarditis 11
HP:0002835 Aspiration 11
HP:0012735 Cough 9
HP:0032255 Opportunistic fungal infection 8
HP:0001138 Optic neuropathy 7
HP:0002860 Squamous cell carcinoma 7
HP:0025044 Lung abscess 7
HP:0100632 Pulmonary sequestration 7
HP:0001370 Rheumatoid arthritis 6
HP:0001394 Cirrhosis 6
HP:0002113 Pulmonary infiltrates 6
HP:0012089 Arteritis 6
HP:0012115 Hepatitis 6
HP:0030078 Lung adenocarcinoma 6
HP:0031273 Shock 6
HP:0100749 Chest pain 6
HP:0000572 Visual loss 5
HP:0001297 Stroke 5
HP:0001913 Granulocytopenia 5
HP:0002583 Colitis 5
HP:0005523 Lymphoproliferative disorder 5
HP:0011109 Chronic sinusitis 5
HP:0032169 Severe infection 5
HP:0001399 Hepatic failure 4
HP:0001735 Acute pancreatitis 4
HP:0001876 Pancytopenia 4
HP:0002039 Anorexia 4
HP:0002108 Spontaneous pneumothorax 4
HP:0002110 Bronchiectasis 4
HP:0002138 Subarachnoid hemorrhage 4
HP:0002586 Peritonitis 4
HP:0010550 Paraplegia 4
HP:0031625 Pseudoaneurysm 4
HP:0040223 Pulmonary hemorrhage 4
HP:0100646 Thyroiditis 4
HP:0000016 Urinary retention 3
HP:0000123 Nephritis 3
HP:0000388 Otitis media 3
HP:0000602 Ophthalmoplegia 3
HP:0001369 Arthritis 3
HP:0001733 Pancreatitis 3
HP:0001824 Weight loss 3
HP:0001880 Eosinophilia 3
HP:0002014 Diarrhea 3
HP:0002027 Abdominal pain 3
HP:0002094 Dyspnea 3
HP:0002170 Intracranial hemorrhage 3
HP:0002202 Pleural effusion 3
HP:0002315 Headache 3
HP:0002664 Neoplasm 3
HP:0002716 Lymphadenopathy 3
HP:0004387 Enterocolitis 3
HP:0004787 Fulminant hepatitis 3
HP:0004937 Pulmonary artery aneurysm 3
HP:0006000 Ureteral obstruction 3
HP:0006517 Alveolar proteinosis 3
HP:0011134 Low-grade fever 3
HP:0012378 Fatigue 3
HP:0012387 Bronchitis 3
HP:0012393 Allergy 3
HP:0032172 Air crescent sign 3
HP:0100279 Ulcerative colitis 3
HP:0100523 Liver abscess 3
HP:0000520 Proptosis 2
HP:0000618 Blindness 2
HP:0000726 Dementia 2
HP:0000969 Edema 2
HP:0000979 Purpura 2
HP:0001342 Cerebral hemorrhage 2
HP:0001541 Ascites 2
HP:0001638 Cardiomyopathy 2
HP:0001658 Myocardial infarction 2
HP:0001873 Thrombocytopenia 2
HP:0001903 Anemia 2
HP:0001974 Leukocytosis 2
HP:0002093 Respiratory insufficiency 2
HP:0002204 Pulmonary embolism 2
HP:0002206 Pulmonary fibrosis 2
HP:0002367 Visual hallucinations 2
HP:0002605 Hepatic necrosis 2
HP:0002719 Recurrent infections 2
HP:0002797 Osteolysis 2
HP:0003095 Septic arthritis 2
HP:0003418 Back pain 2
HP:0003419 Low back pain 2
HP:0004395 Malnutrition 2
HP:0006515 Interstitial pneumonitis 2
HP:0010961 Intralobar sequestration 2
HP:0011675 Arrhythmia 2
HP:0011946 Bronchiolitis obliterans 2
HP:0012203 Onychomycosis 2
HP:0012384 Rhinitis 2
HP:0012722 Heart block 2
HP:0012819 Myocarditis 2
HP:0020102 Pneumocystis jirovecii pneumonia 2
HP:0025421 Pneumomediastinum 2
HP:0030955 Alcoholism 2
HP:0031864 Bacteremia 2
HP:0031944 Pleural thickening 2
HP:0100537 Fasciitis 2
HP:0100570 Carcinoid tumor 2
HP:0100758 Gangrene 2
HP:0200123 Chronic hepatitis 2
HP:0410017 Otitis externa 2
HP:0000010 Recurrent urinary tract infections 1
HP:0000020 Urinary incontinence 1
HP:0000024 Prostatitis 1
HP:0000099 Glomerulonephritis 1
HP:0000100 Nephrotic syndrome 1
HP:0000238 Hydrocephalus 1
HP:0000501 Glaucoma 1
HP:0000508 Ptosis 1
HP:0000518 Cataract 1
HP:0000529 Progressive visual loss 1
HP:0000575 Scotoma 1
HP:0000620 Dacryocystitis 1
HP:0000622 Blurred vision 1
HP:0000790 Hematuria 1
HP:0000821 Hypothyroidism 1
HP:0000822 Hypertension 1
HP:0000836 Hyperthyroidism 1
HP:0000999 Pyoderma 1
HP:0001041 Facial erythema 1
HP:0001250 Seizures 1
HP:0001254 Lethargy 1
HP:0001269 Hemiparesis 1
HP:0001289 Confusion 1
HP:0001300 Parkinsonism 1
HP:0001409 Portal hypertension 1
HP:0001511 Intrauterine growth retardation 1
HP:0001605 Vocal cord paralysis 1
HP:0001681 Angina pectoris 1
HP:0001806 Onycholysis 1
HP:0001878 Hemolytic anemia 1
HP:0001882 Leukopenia 1
HP:0001953 Diabetic ketoacidosis 1
HP:0001993 Ketoacidosis 1
HP:0002013 Vomiting 1
HP:0002020 Gastroesophageal reflux 1
HP:0002097 Emphysema 1
HP:0002102 Pleuritis 1
HP:0002133 Status epilepticus 1
HP:0002140 Ischemic stroke 1
HP:0002196 Myelopathy 1
HP:0002239 Gastrointestinal hemorrhage 1
HP:0002277 Horner syndrome 1
HP:0002352 Leukoencephalopathy 1
HP:0002381 Aphasia 1
HP:0002410 Aqueductal stenosis 1
HP:0002563 Constrictive pericarditis 1
HP:0002575 Tracheoesophageal fistula 1
HP:0002653 Bone pain 1
HP:0002789 Tachypnea 1
HP:0002840 Lymphadenitis 1
HP:0002863 Myelodysplasia 1
HP:0003002 Breast carcinoma 1
HP:0003003 Colon cancer 1
HP:0003198 Myopathy 1
HP:0003201 Rhabdomyolysis 1
HP:0003470 Paralysis 1
HP:0003477 Peripheral axonal neuropathy 1
HP:0004326 Cachexia 1
HP:0004469 Chronic bronchitis 1
HP:0005112 Abdominal aortic aneurysm 1
HP:0005200 Retroperitoneal fibrosis 1
HP:0005214 Intestinal obstruction 1
HP:0005263 Gastritis 1
HP:0005348 Inspiratory stridor 1
HP:0005550 Chronic lymphatic leukemia 1
HP:0005828 Transient pulmonary infiltrates 1
HP:0005987 Multinodular goiter 1
HP:0006280 Chronic pancreatitis 1
HP:0006689 Bacterial endocarditis 1
HP:0006965 Acute necrotizing encephalopathy 1
HP:0007641 Dyschromatopsia 1
HP:0007824 Total ophthalmoplegia 1
HP:0007866 Retinal infarction 1
HP:0008765 Auditory hallucinations 1
HP:0008940 Generalized lymphadenopathy 1
HP:0009830 Peripheral neuropathy 1
HP:0009926 Epiphora 1
HP:0010280 Stomatitis 1
HP:0010962 Extralobar sequestration 1
HP:0011278 Intrapulmonary sequestration 1
HP:0011947 Respiratory tract infection 1
HP:0011950 Bronchiolitis 1
HP:0012032 Lipoma 1
HP:0012085 Pyuria 1
HP:0012109 Angle closure glaucoma 1
HP:0012118 Laryngeal carcinoma 1
HP:0012156 Hemophagocytosis 1
HP:0012213 Decreased glomerular filtration rate 1
HP:0012219 Erythema nodosum 1
HP:0012234 Agranulocytosis 1
HP:0012235 Drug-induced agranulocytosis 1
HP:0012418 Hypoxemia 1
HP:0012486 Myelitis 1
HP:0012490 Panniculitis 1
HP:0012532 Chronic pain 1
HP:0020110 Bone fracture 1
HP:0025059 Splenic abscess 1
HP:0025322 Venous occlusion 1
HP:0025324 Arterial occlusion 1
HP:0030151 Cholangitis 1
HP:0030243 Hepatic vein thrombosis 1
HP:0030358 Non-small cell lung carcinoma 1
HP:0030766 Ear pain 1
HP:0030828 Wheezing 1
HP:0031035 Chronic infection 1
HP:0031589 Suicidal ideation 1
HP:0032101 Unusual infection 1
HP:0032159 Fungal meningitis 1
HP:0032160 Cryptococcal meningitis 1
HP:0032446 Pulmonary bulla 1
HP:0040075 Hypopituitarism 1
HP:0100518 Dysuria 1
HP:0100532 Scleritis 1
HP:0100633 Esophagitis 1
HP:0100653 Optic neuritis 1
HP:0100658 Cellulitis 1
HP:0100727 Histiocytosis 1
HP:0100750 Atelectasis 1
HP:0100773 Cartilage destruction 1
HP:0100825 Cheilitis 1
HP:0200034 Papule 1
HP:0200042 Skin ulcer 1
HP:0410030 Cleft lip 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID