Eosinophilic gastroenteritis

A rare benign gastrointestinal disease characterized by the presence of abnormal and nonspecific gastro-intestinal (GI) manifestations, associated with an eosinophilic infiltration of the GI tract, which can affect several segments and involve several layers within the GI wall.

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Total: 359 (papers)

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Matched Phenotype Gene Mutation MeSH

Rank (Similarity)	PMID (PMCID)
344 (9.2%)	4017826	Eosinophilic colitis. Naylor AR, Pollet JE. Dis Colon Rectum. 1985;28(8):615-8. [ Show abstract ] [ Hide abstract ]
		Allergy


		Colitis Colonic Neoplasms Crohn Disease Differential Diagnosis Eosinophilia Females Homo sapiens
344 (9.2%)	3390775	Eosinophilic enteritis with perforation. Walia HS, Abraham TK, Walia HK. Can J Surg. 1988;31(4):268-9. [ Show abstract ] [ Hide abstract ]
		Allergy


		Enteritis Eosinophilia Females Homo sapiens Intestinal Perforation Jejunal Diseases Middle Aged
344 (9.2%)	2946890	Immune complex glomerulopathy in a child with food hypersensitivity. McCrory WW, Becker CG, Cunningham-Rundles C, Klein RF, Mouradian J, Reisman L. Kidney Int. 1986;30(4):592-8. [ Show abstract ] [ Hide abstract ]
		Glomerulonephritis
		ALB

		Combined Modality Therapy Cross Reactions Dietary Proteins Eosinophilia Food Allergy Gastroenteritis Glomerulonephritis Homo sapiens Immune Complex Diseases Male
354 (5.0%)	14639412	Eosinophilic cellulitis as a cutaneous manifestation of idiopathic hypereosinophilic syndrome. Fujii K, Tanabe H, Kanno Y, Konishi K, Ohgou N. J Am Acad Dermatol. 2003;49(6):1174-7. [ Show abstract ] [ Hide abstract ]
		Polyneuropathy


		Adult Cellulitis Females Homo sapiens Male Middle Aged
354 (5.0%)	12185230	Eosinophilic gastroenteritis mimicking pancreatic cancer. Christopher V, Thompson MH, Hughes S. Postgrad Med J. 2002;78(922):498-9. [ Show abstract ] [ Hide abstract ]
		Carcinoma


		Cholestasis, Extrahepatic Differential Diagnosis Eosinophilia Gastroenteritis Homo sapiens Male Middle Aged Pancreatic Neoplasm
354 (5.0%)	12118924	Carbamazepine-induced eosinophilic enteritis. Shakeer VK, Devi SR, Chettupuzha AP, Mustafa CP, Sandesh K, Kumar SK, Thomas V, Ashraf AS. Indian J Gastroenterol. 2002;21(3):114-5. [ Show abstract ] [ Hide abstract ]
		Seizure


		Anticonvulsants Enteritis Eosinophilia Homo sapiens Male Seizures
354 (5.0%)	10680877	Laryngeal cleft and eosinophilic gastroenteritis: report of 2 cases. Goldstein NA, Putnam PE, Dohar JE. Arch Otolaryngol Head Neck Surg. 2000;126(2):227-30. [ Show abstract ] [ Hide abstract ]
		Laryngeal cleft


		Child, Preschool Eosinophilia Esophagitis Gastroenteritis Homo sapiens Infant Larynx Male
354 (5.0%)	1612991	Eosinophilic gastroenteritis with encapsulated nematodes in a horse. Cohen ND, Loy JK, Lay JC, Craig TM, McMullan WC. J Am Vet Med Assoc. 1992;200(10):1518-20. [ Show abstract ] [ Hide abstract ]
		Weight loss


		Animals Eosinophilia Equus caballus Foot Dermatoses Gastroenteritis Hoof and Claw Horse Diseases Male Strongyle Infections, Equine Strongylus
354 (5.0%)	820590	Fata eosinophilic enteritis. Tytgat GN, Grijm R, Dekker W, Den Hartog NA. Gastroenterology. 1976;71(3):479-83. [ Show abstract ] [ Hide abstract ]
		Overgrowth


		Differential Diagnosis Enteritis Eosinophilia Homo sapiens Intestinal Mucosa Jejunum Male Parenteral Nutrition

Phenotype(s) retrieved from Orphanet

Total: 22

HPO ID	Term	Frequency
HP:0001880	Eosinophilia	Very frequent (99-80%)
HP:0001903	Anemia	Frequent (79-30%)
HP:0001974	Leukocytosis	Frequent (79-30%)
HP:0002013	Vomiting	Frequent (79-30%)
HP:0002014	Diarrhea	Frequent (79-30%)
HP:0002015	Dysphagia	Frequent (79-30%)
HP:0002024	Malabsorption	Frequent (79-30%)
HP:0002027	Abdominal pain	Frequent (79-30%)
HP:0002570	Steatorrhea	Frequent (79-30%)
HP:0003073	Hypoalbuminemia	Frequent (79-30%)
HP:0003193	Allergic rhinitis	Frequent (79-30%)
HP:0011024	Abnormality of the gastrointestinal tract	Frequent (79-30%)
HP:0011227	Elevated C-reactive protein level	Frequent (79-30%)
HP:0500014	obsolete Abnormal test result	Frequent (79-30%)
HP:0000969	Edema	Occasional (29-5%)
HP:0001047	Atopic dermatitis	Occasional (29-5%)
HP:0001541	Ascites	Occasional (29-5%)
HP:0001824	Weight loss	Occasional (29-5%)
HP:0002099	Asthma	Occasional (29-5%)
HP:0002243	Protein-losing enteropathy	Occasional (29-5%)
HP:0002573	Hematochezia	Occasional (29-5%)
HP:0003565	Elevated erythrocyte sedimentation rate	Occasional (29-5%)

Phenotype(s) retrieved from case reports

Total: 88

HPO ID	Term	# of case reports
HP:0001880	Eosinophilia	57
HP:0001541	Ascites	35
HP:0002027	Abdominal pain	18
HP:0002014	Diarrhea	13
HP:0012393	Allergy	13
HP:0002099	Asthma	11
HP:0031780	Eosinophilic ascites	9
HP:0005214	Intestinal obstruction	8
HP:0500093	Food allergy	8
HP:0002013	Vomiting	7
HP:0002024	Malabsorption	5
HP:0001733	Pancreatitis	4
HP:0001891	Iron deficiency anemia	4
HP:0002243	Protein-losing enteropathy	4
HP:0002588	Duodenal ulcer	4
HP:0002595	Ileus	4
HP:0001082	Cholecystitis	3
HP:0001735	Acute pancreatitis	3
HP:0001824	Weight loss	3
HP:0002018	Nausea	3
HP:0002021	Pyloric stenosis	3
HP:0002202	Pleural effusion	3
HP:0002576	Intussusception	3
HP:0004387	Enterocolitis	3
HP:0005263	Gastritis	3
HP:0410281	Dyspepsia	3
HP:0000969	Edema	2
HP:0001903	Anemia	2
HP:0001945	Fever	2
HP:0002028	Chronic diarrhea	2
HP:0002090	Pneumonia	2
HP:0002248	Hematemesis	2
HP:0002583	Colitis	2
HP:0002586	Peritonitis	2
HP:0002592	Gastric ulcer	2
HP:0011458	Abdominal symptom	2
HP:0031368	Intestinal perforation	2
HP:0031370	Small intestinal perforation	2
HP:0032061	Hypereosinophilia	2
HP:0100665	Angioedema	2
HP:0000099	Glomerulonephritis	1
HP:0000819	Diabetes mellitus	1
HP:0000952	Jaundice	1
HP:0000964	Eczema	1
HP:0001025	Urticaria	1
HP:0001081	Cholelithiasis	1
HP:0001271	Polyneuropathy	1
HP:0001279	Syncope	1
HP:0001324	Muscle weakness	1
HP:0001370	Rheumatoid arthritis	1
HP:0001433	Hepatosplenomegaly	1
HP:0001508	Failure to thrive	1
HP:0001744	Splenomegaly	1
HP:0001907	Thromboembolism	1
HP:0002019	Constipation	1
HP:0002043	Esophageal stricture	1
HP:0002254	Intermittent diarrhea	1
HP:0002571	Achalasia	1
HP:0002573	Hematochezia	1
HP:0002664	Neoplasm	1
HP:0002716	Lymphadenopathy	1
HP:0002721	Immunodeficiency	1
HP:0002835	Aspiration	1
HP:0003073	Hypoalbuminemia	1
HP:0003124	Hypercholesterolemia	1
HP:0003193	Allergic rhinitis	1
HP:0005202	Helicobacter pylori infection	1
HP:0006515	Interstitial pneumonitis	1
HP:0006560	Biliary hyperplasia	1
HP:0008751	Laryngeal cleft	1
HP:0009831	Mononeuropathy	1
HP:0012819	Myocarditis	1
HP:0025289	Cervical lymphadenopathy	1
HP:0025428	Bronchospasm	1
HP:0030151	Cholangitis	1
HP:0030731	Carcinoma	1
HP:0031274	Hypovolemic shock	1
HP:0032155	Abdominal cramps	1
HP:0032252	Granuloma	1
HP:0100021	Cerebral palsy	1
HP:0100279	Ulcerative colitis	1
HP:0100537	Fasciitis	1
HP:0100614	Myositis	1
HP:0100633	Esophagitis	1
HP:0100827	Lymphocytosis	1
HP:0200123	Chronic hepatitis	1
HP:0410019	Epigastric pain	1
HP:0410151	Eosinophilic infiltration of the esophagus	1

Causative gene(s) retrieved from Orphanet

Total: 0

Gene Symbol	Gene Name	Entrez Gene ID