IgG4-related kidney disease

A rare renal disease occurring in the setting of a systemic IgG4 related disease. Renal manifestations include tubulointerstitial nephritis (TIN), membranous glomerulonephritis with or without TIN, IgA nephropathy, membranoproliferative glomerulonephritis, mesangioproliferative immune complex glomerulonephritis, sclerosing pyelitis, IgG4-related plasma cell arteritis, and hydronephrosis associated with IgG4 related retroperitoneal fibrosis or ureteral inflammatory pseudotumor. Patients present with acute or chronic renal failure and radiographic mass lesion.



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Narrow down the case reports



Total: 28 (papers)

  


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)
PMID
(PMCID)
3
(4.0%)
27785920
A case of IgG4-related tubulointerstitial nephritis and membranous glomerulonephritis during the clinical course of gastric cancer: Imaging features of IgG4-related kidney disease.
Horita S, Fujii H, Mizushima I, Fujisawa Y, Hara S, Yamada K, Inoue D, Nakajima K, Harada K, Kawano M.
Mod Rheumatol. 2019;29(3):542-546.
Tubulointerstitial nephritis
Aged, 80 and over Homo sapiens Immunoglobulin G4-Related Disease Male Nephritis, Interstitial Stomach Neoplasms
3
(4.0%)
27504450
(4965529)
Coexistence of Acute Crescent Glomerulonephritis and IgG4-Related Kidney Disease.
Lu Z, Yin J, Bao H, Jiao Q, Wu H, Wu R, Xue Q, Wang N, Zhang Z, Wang F.
Case Rep Nephrol Dial. 2016;6(2):89-95.
Glomerulonephritis
3
(4.0%)
27187735
(4977093)
IgG4-Related Kidney Disease in a Patient With History of Breast Cancer: Findings on 18F-FDG PET/CT.
Krebs S, Monti S, Seshan S, Fox J, Mannelli L.
Clin Nucl Med. 2016;41(8):e388-9.
Weight loss
Autoimmune Diseases Carcinoma Differential Diagnosis Females Homo sapiens Middle Aged Nephritis Radiopharmaceuticals
3
(4.0%)
26817905
(4998279)
IgG4-related Kidney Disease Mimicking Malignant Ureter Tumor: Case Report and Literature Review.
Lei WH, Xin J, Shao CX, Mao MF, Zhu CY, Wu CF, Jin L.
Medicine (Baltimore). 2016;95(3):e2550.
Hydronephrosis
Autoimmune Diseases Homo sapiens Kidney Male Nephritis, Interstitial Ureteral Neoplasms
3
(4.0%)
26770608
IgG4-related tubulointerstitial nephritis associated with only lymphadenopathy and without elevated serum IgG4 or renal imaging abnormalities: a case report and literature review.
Qiao X, Wang L, Wang C, Gao L, Yao S, Wu L, Zhang X.
Int J Clin Exp Med. 2015;8(10):19548-55.
Tubulointerstitial nephritis
3
(4.0%)
26502965
(4624354)
Membranoproliferative glomerulonephritis with predominant IgG2 and IgG3 deposition in a patient with IgG4-related disease.
Ueki K, Matsukuma Y, Masutani K, Tsuchimoto A, Fujisaki K, Torisu K, Tanaka S, Kiyoshima T, Hisano S, Kitazono T, Tsuruya K.
BMC Nephrol. 2015;16:173.
Glomerulonephritis
IGHG3
Females Glomerulonephritis, Membranoproliferative Homo sapiens Kidney Glomerulus Nephritis, Interstitial Plasma Cells
3
(4.0%)
26338167
Immunoglobulin G4-related Kidney Disease as a Cause of Acute Renal Insufficiency.
Li C, Du XG.
Iran J Kidney Dis. 2015;9(5):409-11.
Renal insufficiency
Autoimmune Diseases Homo sapiens Kidney Kidney Diseases Male X-Ray Computed Tomography
3
(4.0%)
26015827
(4432904)
An Overlapping Case of Lupus Nephritis and IgG4-Related Kidney Disease.
Zaarour M, Weerasinghe C, Eter A, El-Sayegh S, El-Charabaty E.
J Clin Med Res. 2015;7(7):575-81.
Proteinuria
3
(4.0%)
26013281
(4446108)
IgG4-related kidney disease from the renal pelvis that mimicked urothelial carcinoma: a case report.
Zhang H, Ren X, Zhang W, Yang D, Feng R.
BMC Urol. 2015;15:44.
Tubulointerstitial nephritis
Carcinoma, Transitional Cell Differential Diagnosis Females Homo sapiens Immunohistochemistry Kidney Neoplasm Middle Aged Nephrectomy Nephritis Positron-Emission Tomography X-Ray Computed Tomography
3
(4.0%)
25986266
IgG4-related Kidney Disease in Which the Urinalysis, Kidney Function and Imaging Findings Were Normal.
Otani M, Morinaga M, Nakajima Y, Tomioka H, Nishii M, Inoue Y, Ikeda T, Morimoto M, Katsuyama E, Tsunoda S.
Intern Med. 2015;54(10):1253-7.
Proteinuria
Autoimmune Diseases Biopsy Diagnostic Imaging Homo sapiens Kidney Diseases Kidney Function Tests Male Middle Aged Urinalysis
        

Phenotype(s) retrieved from Orphanet

    Total: 0

HPO ID Term Frequency


Phenotype(s) retrieved from case reports

    Total: 11

HPO ID Term # of case reports
HP:0001970 Tubulointerstitial nephritis 5
HP:0000123 Nephritis 4
HP:0000024 Prostatitis 2
HP:0000099 Glomerulonephritis 2
HP:0012578 Membranous nephropathy 2
HP:0000083 Renal insufficiency 1
HP:0000793 Membranoproliferative glomerulonephritis 1
HP:0001919 Acute kidney injury 1
HP:0005576 Tubulointerstitial fibrosis 1
HP:0030151 Cholangitis 1
HP:0030731 Carcinoma 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID