IgG4-related kidney disease

A rare renal disease occurring in the setting of a systemic IgG4 related disease. Renal manifestations include tubulointerstitial nephritis (TIN), membranous glomerulonephritis with or without TIN, IgA nephropathy, membranoproliferative glomerulonephritis, mesangioproliferative immune complex glomerulonephritis, sclerosing pyelitis, IgG4-related plasma cell arteritis, and hydronephrosis associated with IgG4 related retroperitoneal fibrosis or ureteral inflammatory pseudotumor. Patients present with acute or chronic renal failure and radiographic mass lesion.



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Narrow down the case reports



Total: 28 (papers)

  


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)
PMID
(PMCID)
1
(36.8%)
25849674
(4360725)
Acute Interstitial Nephritis and Membranous Nephropathy in the Context of IgG4-Related Disease.
Stylianou K, Maragkaki E, Tzanakakis M, Stratakis S, Gakiopoulou H, Daphnis E.
Case Rep Nephrol Dial. 2015;5(1):44-8.
Facial palsy Sialadenitis
2
(27.8%)
25838652
(4379619)
Immunoglobulin G4-related tubulointerstitial nephritis associated with interstitial pulmonary disease: Report of a case with review of literature.
Saravanan M, Alexander S, Matthai SM, Korula A, Varughese S, Tamilarasi V.
Indian J Nephrol. 2015;25(2):113-6.
Tubulointerstitial nephritis Sialadenitis
3
(4.0%)
31192228
IgG4-Related Kidney Disease: A Curious Case of Interstitial Nephritis with Hypocomplementemia.
Wong ETY, Lahiri M, Teh M, Leo CCH.
Case Rep Nephrol Dial. 2019;9(2):49-54.
Nephritis
3
(4.0%)
30651091
Simultaneous occurrence of IgG4-related Tubulointerstitial nephritis and colon adenocarcinoma with hepatic metastasis: a case report and literature review.
Gou SJ, Xue LJ, Hu ZX.
BMC Nephrol. 2019;20(1):23.
Tubulointerstitial nephritis
Adenocarcinoma Biopsy Colonic Neoplasms Fatal Outcome Homo sapiens Kidney Male Nephritis, Interstitial Plasma Cells
3
(4.0%)
30544121
Immunoglobulin G4-Related Disease Arising from the Bladder Wall.
Kufukihara R, Niwa N, Mizuno R, Ohara K, Mikami S, Kikuchi E, Oya M.
Urol Int. 2018;:1-3.
Prostatitis
Homo sapiens Immunoglobulin G4-Related Disease Male Urinary Bladder Diseases
3
(4.0%)
30458736
(6245818)
An IgA1-lambda-type monoclonal immunoglobulin deposition disease associated with membranous features in a patient with IgG4-related kidney disease: a case report.
Kitazawa A, Koda R, Yoshino A, Ueda Y, Takeda T.
BMC Nephrol. 2018;19(1):330.
Proteinuria
IGHA1
Homo sapiens Immunoglobulin G4-Related Disease Male Nephritis, Interstitial
3
(4.0%)
30087220
Immunoglobulin G4-related Kidney Disease Associated With Autoimmune Hemolytic Anemia.
Gou SJ, Yu SB, Qiu HY, Hu ZX.
Iran J Kidney Dis. 2018;12(4):243-246.
Anemia
Adrenal Cortex Hormones Autoimmune Diseases Biological Markers Biopsy Homo sapiens Immunohistochemistry Kidney Kidney Diseases Male
3
(4.0%)
29709946
(6207830)
A Refractory Case of Secondary Membranous Nephropathy Concurrent with IgG4-related Tubulointerstitial Nephritis.
Arai H, Toda N, Kamimatsuse R, Nishioka K, Endo S, Akiyama S, Maruyama S, Matsubara T, Yokoi H, Yanagita M.
Intern Med. 2018;57(19):2873-2877.
Proteinuria
Anti-Inflammatory Agents Homo sapiens Immunoglobulin G4-Related Disease Immunosuppressive Agents Male Middle Aged Nephritis, Interstitial Nephrotic Syndrome Pancreatitis Proteinuria
3
(4.0%)
28912998
(5585603)
IgG4-Related Kidney Disease: Report of a Case Presenting as a Renal Mass.
Bianchi D, Topazio L, Gaziev G, Iacovelli V, Bove P, Mauriello A, Finazzi Agro E.
Case Rep Surg. 2017;2017:9690218.
Moderate albuminuria
3
(4.0%)
28552902
(5459220)
IgG4-Related Disease Manifesting as Interstitial Nephritis Accompanied by Hypophysitis.
Matsuda K, Saito A, Takeuchi Y, Fukami H, Sato H, Nagasawa T.
Am J Case Rep. 2017;18:593-598.
Polyuria
Aged, 80 and over Autoimmune Hypophysitis Diabetes Insipidus Homo sapiens Male Nephritis, Interstitial
        

Phenotype(s) retrieved from Orphanet

    Total: 0

HPO ID Term Frequency


Phenotype(s) retrieved from case reports

    Total: 11

HPO ID Term # of case reports
HP:0001970 Tubulointerstitial nephritis 5
HP:0000123 Nephritis 4
HP:0000024 Prostatitis 2
HP:0000099 Glomerulonephritis 2
HP:0012578 Membranous nephropathy 2
HP:0000083 Renal insufficiency 1
HP:0000793 Membranoproliferative glomerulonephritis 1
HP:0001919 Acute kidney injury 1
HP:0005576 Tubulointerstitial fibrosis 1
HP:0030151 Cholangitis 1
HP:0030731 Carcinoma 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID