Carcinosarcoma of the corpus uteri

Carcinosarcoma of the corpus uteri is a rare, malignant, mixed epithelial and mesenchymal tumor of the uterine body composed of high-grade carcinomatous and sarcomatous elements. It may present with vaginal bleeding, abnormal vaginal discharge, abdominal pain and/or pelvic mass, with a polypoid tumor sometimes protruding through the cervical canal. Association with Tamoxifen therapy, long-term unopposed estrogen use and previous pelvic radiotherapy has been reported.



Input patient's signs and symptoms


Narrow down the case reports



Total: 46 (papers)

   


(per page)
Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
1
(20.4%)		 23871174
 Metastatic calcaneal lesion associated with uterine carcinosarcoma.
Rice BM, Todd NW, Jensen R, Rush SM, Rogers W.
J Foot Ankle Surg. 2014;53(3):364-8.
Edema Foot pain
Aged, 80 and over Carcinosarcoma Females Homo sapiens Uterine Neoplasms
2
(4.0%)		 31149529
 A case of uterine carcinosarcoma which was strongly suspected to have metastases to the psoas and gluteus muscles.
Ishidera Y, Yoshida H, Oi Y, Katayama K, Ando N, Shigeta H.
Int Cancer Conf J. 2018;7(4):121-124.
Ascites
2
(4.0%)		 30345891
 Uterine carcinosarcoma (malignant mixed Mullerian tumor): case report in a goat and literature review.
Cossic B, Hill JA, Cercone M, Southard T.
J Vet Diagn Invest. 2018;30(6):955-961.
Lethargy
Animals Differential Diagnosis Females Goat Goat Diseases Immunohistochemistry Mixed Tumor, Mullerian Uterine Neoplasms
2
(4.0%)		 30308682
 Radiation-Induced Uterine Carcinosarcoma after Concurrent Chemoradiotherapy for Cervical Squamous Cell Carcinoma.
Moreira-Barros J, Huang KG, Tsai TH.
Rev Bras Ginecol Obstet. 2018;40(12):800-802.
Carcinoma
Carcinosarcoma Chemoradiotherapy Fatal Outcome Females Homo sapiens Middle Aged Neoplasms, Radiation-Induced Uterine Cervical Neoplasm Uterine Neoplasms
2
(4.0%)		 30057538
(6062688)
 A Case of Uterine Carcinosarcoma Detected Simultaneously with Breast and Colon Cancer (Triple Primary Malignant Tumor).
Lee E, Ji YI.
Case Rep Oncol. 2018;11(2):431-435.
Colon cancer
2
(4.0%)		 29992073
(6016168)
 Uterine Carcinosarcoma with Alpha-Fetoprotein-Producing Hepatoid Component: A Case Report and Literature Review.
Li JJX, Lee JHS, Chan VTC, Yu MY.
Case Rep Pathol. 2018;2018:3972353.
Ascites
AFP ARG1
2
(4.0%)		 28761924
(5524167)
 Secondary uterine carcinosarcoma after concurrent chemoradiotherapy for cervical cancer: Case reports.
Wakayama A, Kudaka W, Nakasone T, Taira Y, Aoki Y.
Gynecol Oncol Rep. 2017;21:81-83.
Sarcoma
2
(4.0%)		 28546804
(5437056)
 Synchronous uterine adenocarcinoma and leiomyosarcoma - a case study.
Dudzik K, Krzysteczko A, Kolny L, Bk A, Stawicka-Ociepka E, Nowosielski K.
Prz Menopauzalny. 2017;16(1):23-25.
Carcinoma
2
(4.0%)		 28424084
(5397750)
 Durable complete remission with aromatase inhibitor therapy in a patient with metastatic uterine carcinosarcoma with poor performance status and coagulation disorders: a case report.
Martin-Romano P, Jurado M, Idoate MA, Arbea L, Hernandez-Lizoain JL, Cano D, Paramo JA, Martin-Algarra S.
J Med Case Rep. 2017;11(1):115.
Hypovolemic shock
Aromatase Inhibitors Blood Coagulation Disorders Carcinosarcoma Females Homo sapiens Lymphatic Metastasis Middle Aged Nitriles Remission Induction Shock Triazoles Uterine Neoplasms
2
(4.0%)		 27073665
 Carcinosarcoma of the uterus: A case report.
Adachi Y, Nonogaki H, Minamiguchi S, Li M, Ikehara S.
Mol Clin Oncol. 2016;4(4):571-573.
Anemia
        

Phenotype(s) retrieved from Orphanet

    Total: 0

HPO ID Term Frequency


Phenotype(s) retrieved from case reports

    Total: 11

HPO ID Term # of case reports
HP:0030731 Carcinoma 7
HP:0100242 Sarcoma 3
HP:0001903 Anemia 2
HP:0000718 Aggressive behavior 1
HP:0001548 Overgrowth 1
HP:0001698 Pericardial effusion 1
HP:0002664 Neoplasm 1
HP:0002835 Aspiration 1
HP:0002860 Squamous cell carcinoma 1
HP:0003003 Colon cancer 1
HP:0012114 Endometrial carcinoma 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID