Carcinosarcoma of the corpus uteri

Carcinosarcoma of the corpus uteri is a rare, malignant, mixed epithelial and mesenchymal tumor of the uterine body composed of high-grade carcinomatous and sarcomatous elements. It may present with vaginal bleeding, abnormal vaginal discharge, abdominal pain and/or pelvic mass, with a polypoid tumor sometimes protruding through the cervical canal. Association with Tamoxifen therapy, long-term unopposed estrogen use and previous pelvic radiotherapy has been reported.



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Total: 46 (papers)

   


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Matched Phenotype  Gene  Mutation  MeSH
Rank
(Similarity)		 PMID
(PMCID)
2
(4.0%)		 8971564
 Carcinosarcoma of the uterus with extensive neuroectodermal differentiation.
Fukunaga M, Nomura K, Endo Y, Ushigome S, Aizawa S.
Histopathology. 1996;29(6):565-70.
Squamous cell carcinoma
B3GAT1 ENO2 SYP
Biological Markers Carcinosarcoma Differential Diagnosis Females Homo sapiens Immunoenzyme Techniques Middle Aged Neuroectodermal Tumor, Primitive Uterine Neoplasms
2
(4.0%)		 8313481
 [Uterine mixed malignant mesodermal tumors--a case with an unusual distribution of components].
Zamecnik M.
Cesk Patol. 1993;29(4):147-9.
Carcinoma
Females Homo sapiens Uterine Neoplasms
2
(4.0%)		 7661577
 [A case of remission of recurrent carcinosarcoma of the uterus with massive ascites by carboplatin].
Takada S, Tamura A, Hiraoka K, Ogino M, Mori H, Imamura T.
Gan To Kagaku Ryoho. 1995;22(9):1253-6.
Ascites
Ascitic Fluid Carcinosarcoma Females Homo sapiens Remission Induction Uterine Neoplasms
2
(4.0%)		 7230832
 Uterine sarcoma following adjuvant radiotherapy for rectal carcinoma.
Marmion PJ, Goldfarb PM, Youngkin TP.
J Surg Oncol. 1981;17(1):63-7.
Carcinoma
Adenocarcinoma Females Homo sapiens Middle Aged Neoplasms, Radiation-Induced Rectal Neoplasms Sarcoma Uterine Neoplasms
2
(4.0%)		 7194144
 Histogenesis and culture of human uterine carcinosarcoma.
Ishiwata I, Ishiwata C, Nagayama T, Ishikawa H.
Cancer Res. 1981;41(5):1978-83.
Endometrial carcinoma
Adenocarcinoma Animals Carcinosarcoma Cultured Cells Females Homo sapiens Mice, Nude Middle Aged Mus Neoplasm Transplantation Sarcoma Uterine Neoplasms
2
(4.0%)		 2435929
 [A case report of uterine carcinosarcoma with alpha-fetoprotein (AFP) production].
Shigemasa K, Myoga H, Nakanishi Y, Imajo M, Yorishima M, Matsuda H, Hung CC, Egawa K, Katsube Y, Fujiwara A.
Gan No Rinsho. 1987;33(2):223-9.
Sarcoma
Carcinosarcoma Combined Modality Therapy Females Homo sapiens Uterine Neoplasms alpha-Fetoproteins
        

Phenotype(s) retrieved from Orphanet

    Total: 0

HPO ID Term Frequency


Phenotype(s) retrieved from case reports

    Total: 11

HPO ID Term # of case reports
HP:0030731 Carcinoma 7
HP:0100242 Sarcoma 3
HP:0001903 Anemia 2
HP:0000718 Aggressive behavior 1
HP:0001548 Overgrowth 1
HP:0001698 Pericardial effusion 1
HP:0002664 Neoplasm 1
HP:0002835 Aspiration 1
HP:0002860 Squamous cell carcinoma 1
HP:0003003 Colon cancer 1
HP:0012114 Endometrial carcinoma 1


Causative gene(s) retrieved from Orphanet

    Total: 0

Gene Symbol Gene Name Entrez Gene ID