| Rank (Similarity) |
PMID (PMCID) |
|
|---|---|---|
| 1 (48.9%) |
3414079 |
[Mixed connective tissue disease (Sharp's syndrome)--a case report]. Gatsev Z, Vulev S. Vutr Boles. 1988;27(1):114-7. |
| Arthritis Hepatosplenomegaly Anemia | ||
| Differential Diagnosis Females Homo sapiens Middle Aged Mixed Connective Tissue Disease | ||
| 2 (46.2%) |
28700492 (5515764) |
An unusual association between hemophagocytic lymphohistiocytosis, mixed connective tissue disease, and autoimmune hemolytic anemia: A case report. Kelkar AH, Shah AA, Yong SL, Ahmed Z. Medicine (Baltimore). 2017;96(28):e7488. |
| Splenomegaly Pancytopenia Fever Hepatitis | ||
| Adult Differential Diagnosis Females Homo sapiens Lymphohistiocytosis, Hemophagocytic Mixed Connective Tissue Disease | ||
| 3 (42.8%) |
7732496 |
[A case of mixed connective tissue disease associated with gastric cancer and cancer of the uterine cervix]. Katayama M, Tanaka I, Hosako Y, Hama N, Yamada T, Inada S, Goto M. Ryumachi. 1995;35(1):85-9. |
| Leukopenia Fever Lymphadenopathy Erythema | ||
| SSB TRIM21 | ||
| Adenocarcinoma Adult Females Homo sapiens Mixed Connective Tissue Disease Neoplasms, Multiple Primary Stomach Neoplasms Uterine Cervical Neoplasm | ||
| 4 (39.1%) |
19718594 |
[Severe corticoid-refractory autoimmune thrombocytopenia associated with mixed connective tissue disease (Sharp's syndrome). Treatment with rituximab]. Rudolph SE, Kouba M, Hrdlicka P. Dtsch Med Wochenschr. 2009;134(36):1734-8. |
| Splenomegaly Thrombocytopenia | ||
| Antibodies, Monoclonal, Murine-Derived B-Lymphocytes Females Glucocorticoids Homo sapiens Immunologic Factors Mixed Connective Tissue Disease Monoclonal Antibodies Refusal of Treatment Splenectomy | ||
| 5 (38.2%) |
1411796 |
[A case of Sweet's syndrome (acute febrile neutrophilic dermatosis) associated with mixed connective tissue disease]. Makino Y, Ueda S, Ogawa M, Hori J, Ohto M, Wakashin M, Tanabe E. Ryumachi. 1992;32(4):340-5; discussion 345-6. |
| Fever Leukocytosis Erythema | ||
| PIK3C2A | ||
| Homo sapiens Male Middle Aged Mixed Connective Tissue Disease Sweet Syndrome | ||
| 6 (37.6%) |
583290 |
[Scleroderma with traces of disseminated lupus erythematosus associated with Hashimoto's thyroiditis and papillary carcinoma of the thyroid gland (author's transl)]. Sanchez de Rivera JM, Barbado Hernandez FJ, Vazquez Rodriguez JJ, Gil Aguado A, Garcia Puig J, Viguer Garcia-Moreno JM. Med Clin (Barc). 1979;73(8):342-6. |
| Hypertension Leukopenia Anemia Fever | ||
| Carcinoma, Papillary Differential Diagnosis Females Homo sapiens Lupus Erythematosus, Systemic Middle Aged Systemic Scleroderma Thyroid Neoplasm | ||
| 7 (37.3%) |
20847509 |
Idiopathic portal hypertension in a patient with mixed connective tissue disease and protein C deficiency. Horai Y, Miyamura T, Hirata A, Nakamura M, Takahama S, Ando H, Minami R, Yamamoto M, Suematsu E. Intern Med. 2010;49(18):2013-6. |
| Portal hypertension Thrombocytopenia Hypersplenism | ||
| Adult Females Homo sapiens Liver Cirrhosis Mixed Connective Tissue Disease Pancytopenia Portal Hypertension Protein C Deficiency Splenomegaly | ||
| 8 (33.8%) |
7974030 |
[Hemophagocytic syndrome observed in a patient with systemic lupus erythematosus]. Hayashi S, Nawata Y, Takabayashi K, Iwamoto I, Yoshida S. Ryumachi. 1994;34(4):779-85. |
| Skin rash Pancytopenia Fever | ||
| Disseminated Intravascular Coagulation Females Fever Histiocytosis, Non-Langerhans-Cell Homo sapiens Lupus Erythematosus, Systemic Middle Aged | ||
| 9 (33.4%) |
22579274 (4293699) |
Differentiating scleroderma renal crisis from other causes of thrombotic microangiopathy in a postpartum patient. Abudiab M, Krause ML, Fidler ME, Nath KA, Norby SM. Clin Nephrol. 2013;80(4):293-7. |
| Thrombocytopenia Hemolytic anemia Fever | ||
| ACE | ||
| Adult Biopsy Differential Diagnosis Females Homo sapiens Plasma Exchange Postpartum Period Purpura, Thrombotic Thrombocytopenic Renal Dialysis Systemic Scleroderma | ||
| 9 (33.4%) |
21915182 (3170900) |
Thrombotic thrombocytopenic purpura associated with mixed connective tissue disease: a case report. Souto Filho JT, de Barros PV, da Silva AM, Barbosa FA, Ribas GF. Case Rep Med. 2011;2011:953890. |
| Thrombocytopenia Hemolytic anemia Fever | ||
Total: 41
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0000988 | Skin rash | Very frequent (99-80%) |
| HP:0001369 | Arthritis | Very frequent (99-80%) |
| HP:0002020 | Gastroesophageal reflux | Very frequent (99-80%) |
| HP:0002094 | Dyspnea | Very frequent (99-80%) |
| HP:0002206 | Pulmonary fibrosis | Very frequent (99-80%) |
| HP:0002960 | Autoimmunity | Very frequent (99-80%) |
| HP:0003326 | Myalgia | Very frequent (99-80%) |
| HP:0003565 | Elevated erythrocyte sedimentation rate | Very frequent (99-80%) |
| HP:0005263 | Gastritis | Very frequent (99-80%) |
| HP:0012378 | Fatigue | Very frequent (99-80%) |
| HP:0100324 | Scleroderma | Very frequent (99-80%) |
| HP:0100749 | Chest pain | Very frequent (99-80%) |
| HP:0000217 | Xerostomia | Frequent (79-30%) |
| HP:0000709 | Psychosis | Frequent (79-30%) |
| HP:0001097 | Keratoconjunctivitis sicca | Frequent (79-30%) |
| HP:0001386 | Joint swelling | Frequent (79-30%) |
| HP:0001945 | Fever | Frequent (79-30%) |
| HP:0002102 | Pleuritis | Frequent (79-30%) |
| HP:0002829 | Arthralgia | Frequent (79-30%) |
| HP:0100614 | Myositis | Frequent (79-30%) |
| HP:0000112 | Nephropathy | Occasional (29-5%) |
| HP:0000979 | Purpura | Occasional (29-5%) |
| HP:0001250 | Seizures | Occasional (29-5%) |
| HP:0001287 | Meningitis | Occasional (29-5%) |
| HP:0001387 | Joint stiffness | Occasional (29-5%) |
| HP:0001596 | Alopecia | Occasional (29-5%) |
| HP:0001701 | Pericarditis | Occasional (29-5%) |
| HP:0001744 | Splenomegaly | Occasional (29-5%) |
| HP:0001878 | Hemolytic anemia | Occasional (29-5%) |
| HP:0001882 | Leukopenia | Occasional (29-5%) |
| HP:0002092 | Pulmonary arterial hypertension | Occasional (29-5%) |
| HP:0002239 | Gastrointestinal hemorrhage | Occasional (29-5%) |
| HP:0002240 | Hepatomegaly | Occasional (29-5%) |
| HP:0002716 | Lymphadenopathy | Occasional (29-5%) |
| HP:0002797 | Osteolysis | Occasional (29-5%) |
| HP:0003010 | Prolonged bleeding time | Occasional (29-5%) |
| HP:0006530 | Interstitial pulmonary abnormality | Occasional (29-5%) |
| HP:0009830 | Peripheral neuropathy | Occasional (29-5%) |
| HP:0010885 | Avascular necrosis | Occasional (29-5%) |
| HP:0012819 | Myocarditis | Occasional (29-5%) |
| HP:0100721 | Mediastinal lymphadenopathy | Occasional (29-5%) |
Total: 137
| HPO ID | Term | # of case reports |
|---|---|---|
| HP:0000822 | Hypertension | 28 |
| HP:0001370 | Rheumatoid arthritis | 22 |
| HP:0000099 | Glomerulonephritis | 9 |
| HP:0002090 | Pneumonia | 9 |
| HP:0001369 | Arthritis | 8 |
| HP:0001873 | Thrombocytopenia | 6 |
| HP:0100614 | Myositis | 6 |
| HP:0001701 | Pericarditis | 5 |
| HP:0100646 | Thyroiditis | 5 |
| HP:0000100 | Nephrotic syndrome | 4 |
| HP:0000819 | Diabetes mellitus | 4 |
| HP:0000821 | Hypothyroidism | 4 |
| HP:0001287 | Meningitis | 4 |
| HP:0002206 | Pulmonary fibrosis | 4 |
| HP:0012486 | Myelitis | 4 |
| HP:0012819 | Myocarditis | 4 |
| HP:0000083 | Renal insufficiency | 3 |
| HP:0001698 | Pericardial effusion | 3 |
| HP:0001945 | Fever | 3 |
| HP:0002196 | Myelopathy | 3 |
| HP:0007618 | Subcutaneous calcification | 3 |
| HP:0012115 | Hepatitis | 3 |
| HP:0030731 | Carcinoma | 3 |
| HP:0030880 | Raynaud phenomenon | 3 |
| HP:0000855 | Insulin resistance | 2 |
| HP:0000939 | Osteoporosis | 2 |
| HP:0001138 | Optic neuropathy | 2 |
| HP:0001297 | Stroke | 2 |
| HP:0001298 | Encephalopathy | 2 |
| HP:0001324 | Muscle weakness | 2 |
| HP:0001409 | Portal hypertension | 2 |
| HP:0001618 | Dysphonia | 2 |
| HP:0001658 | Myocardial infarction | 2 |
| HP:0001937 | Microangiopathic hemolytic anemia | 2 |
| HP:0002024 | Malabsorption | 2 |
| HP:0002094 | Dyspnea | 2 |
| HP:0002113 | Pulmonary infiltrates | 2 |
| HP:0002243 | Protein-losing enteropathy | 2 |
| HP:0002381 | Aphasia | 2 |
| HP:0002716 | Lymphadenopathy | 2 |
| HP:0005521 | Disseminated intravascular coagulation | 2 |
| HP:0011838 | Sclerodactyly | 2 |
| HP:0012490 | Panniculitis | 2 |
| HP:0012735 | Cough | 2 |
| HP:0025421 | Pneumomediastinum | 2 |
| HP:0100008 | Schwannoma | 2 |
| HP:0100584 | Endocarditis | 2 |
| HP:0100598 | Pulmonary edema | 2 |
| HP:0100806 | Sepsis | 2 |
| HP:0200042 | Skin ulcer | 2 |
| HP:0200120 | Chronic active hepatitis | 2 |
| HP:0000112 | Nephropathy | 1 |
| HP:0000123 | Nephritis | 1 |
| HP:0000133 | Gonadal dysgenesis | 1 |
| HP:0000709 | Psychosis | 1 |
| HP:0000763 | Sensory neuropathy | 1 |
| HP:0000969 | Edema | 1 |
| HP:0000979 | Purpura | 1 |
| HP:0001258 | Spastic paraplegia | 1 |
| HP:0001399 | Hepatic failure | 1 |
| HP:0001482 | Subcutaneous nodule | 1 |
| HP:0001513 | Obesity | 1 |
| HP:0001541 | Ascites | 1 |
| HP:0001635 | Congestive heart failure | 1 |
| HP:0001638 | Cardiomyopathy | 1 |
| HP:0001663 | Ventricular fibrillation | 1 |
| HP:0001664 | Torsade de pointes | 1 |
| HP:0001700 | Myocardial necrosis | 1 |
| HP:0001733 | Pancreatitis | 1 |
| HP:0001876 | Pancytopenia | 1 |
| HP:0001878 | Hemolytic anemia | 1 |
| HP:0001882 | Leukopenia | 1 |
| HP:0001903 | Anemia | 1 |
| HP:0001907 | Thromboembolism | 1 |
| HP:0001919 | Acute kidney injury | 1 |
| HP:0001942 | Metabolic acidosis | 1 |
| HP:0001953 | Diabetic ketoacidosis | 1 |
| HP:0001971 | Hypersplenism | 1 |
| HP:0002014 | Diarrhea | 1 |
| HP:0002018 | Nausea | 1 |
| HP:0002040 | Esophageal varix | 1 |
| HP:0002041 | Intractable diarrhea | 1 |
| HP:0002045 | Hypothermia | 1 |
| HP:0002098 | Respiratory distress | 1 |
| HP:0002100 | Recurrent aspiration pneumonia | 1 |
| HP:0002102 | Pleuritis | 1 |
| HP:0002105 | Hemoptysis | 1 |
| HP:0002107 | Pneumothorax | 1 |
| HP:0002202 | Pleural effusion | 1 |
| HP:0002239 | Gastrointestinal hemorrhage | 1 |
| HP:0002240 | Hepatomegaly | 1 |
| HP:0002248 | Hematemesis | 1 |
| HP:0002315 | Headache | 1 |
| HP:0002480 | Hepatic encephalopathy | 1 |
| HP:0002586 | Peritonitis | 1 |
| HP:0002617 | Dilatation | 1 |
| HP:0002878 | Respiratory failure | 1 |
| HP:0002955 | Granulomatosis | 1 |
| HP:0002960 | Autoimmunity | 1 |
| HP:0003072 | Hypercalcemia | 1 |
| HP:0003073 | Hypoalbuminemia | 1 |
| HP:0003198 | Myopathy | 1 |
| HP:0003270 | Abdominal distention | 1 |
| HP:0003761 | Calcinosis | 1 |
| HP:0004389 | Intestinal pseudo-obstruction | 1 |
| HP:0004942 | Aortic aneurysm | 1 |
| HP:0005550 | Chronic lymphatic leukemia | 1 |
| HP:0005575 | Hemolytic-uremic syndrome | 1 |
| HP:0006946 | Recurrent meningitis | 1 |
| HP:0007209 | Facial paralysis | 1 |
| HP:0009071 | Inflammatory myopathy | 1 |
| HP:0009830 | Peripheral neuropathy | 1 |
| HP:0011703 | Sinus tachycardia | 1 |
| HP:0012089 | Arteritis | 1 |
| HP:0012234 | Agranulocytosis | 1 |
| HP:0012473 | Tongue atrophy | 1 |
| HP:0012578 | Membranous nephropathy | 1 |
| HP:0012636 | Retinal vein occlusion | 1 |
| HP:0025343 | Lupus anticoagulant | 1 |
| HP:0025615 | Abscess | 1 |
| HP:0025637 | Vasospasm | 1 |
| HP:0030350 | Erythematous papule | 1 |
| HP:0030430 | Neuroma | 1 |
| HP:0030773 | Internuclear ophthalmoplegia | 1 |
| HP:0031179 | Nuchal rigidity | 1 |
| HP:0031678 | Atherosclerotic lesion | 1 |
| HP:0032252 | Granuloma | 1 |
| HP:0040049 | Macular edema | 1 |
| HP:0100532 | Scleritis | 1 |
| HP:0100537 | Fasciitis | 1 |
| HP:0100658 | Cellulitis | 1 |
| HP:0100718 | Uterine rupture | 1 |
| HP:0100749 | Chest pain | 1 |
| HP:0100762 | Hemobilia | 1 |
| HP:0100790 | Hernia | 1 |
| HP:0200034 | Papule | 1 |
| HP:0200119 | Acute hepatitis | 1 |
Total: 0
| Gene Symbol | Gene Name | Entrez Gene ID |
|---|