| Rank (Similarity) |
PMID (PMCID) |
|
|---|---|---|
| 11 (60.6%) |
24629905 |
[Aplastic crisis due to parvovirus B19 and Epstein-Barr virus in a patient with hereditary spherocytosis]. Leoz Gordillo I, Perez Suarez E. An Pediatr (Barc). 2015;82(1):e102-7. |
| Jaundice Hepatosplenomegaly Anemia Fever | ||
| Anemia, Hemolytic Child, Preschool Epstein-Barr Virus Infections Erythema Infectiosum Females Homo sapiens | ||
| 11 (60.6%) |
686044 |
Extreme hyperbilirubinemia in a patient with hereditary spherocytosis, Gilbert's syndrome, and obstructive jaundice. Katz ME, Weinstein IM. Am J Med Sci. 1978;275(3):373-9. |
| Jaundice Hepatosplenomegaly Anemia Hyperbilirubinemia | ||
| Cholestasis Erythrocyte Aging Homo sapiens Hyperbilirubinemia Hyperbilirubinemia, Hereditary Male | ||
| 13 (60.1%) |
21378480 |
[Low-titer cold agglutinin disease following Salmonella gastroenteritis]. Kobayashi K, Hamaki T, Ohwada A, Tomiyama J, Sakuma R, Mizuta Y, Moriyama A, Yamamoto E, Akiya I, Fujita H. Rinsho Ketsueki. 2011;52(1):32-6. |
| Cyanosis Anemia Fever Diarrhea Spherocytosis | ||
| Anemia, Hemolytic Gastroenteritis Homo sapiens Male Middle Aged | ||
| 14 (59.8%) |
26073240 |
Hereditary Spherocytosis in a Middle-aged Man Complicated with Common Bile Duct Stones. Sawahara H, Iwamuro M, Harada R, Yoshioka M, Niguma T, Mimura T, Yamamoto K. Intern Med. 2015;54(12):1509-12. |
| Cholelithiasis Splenomegaly Hemolytic anemia Hyperbilirubinemia | ||
| Cholecystectomy, Laparoscopic Homo sapiens Hyperbilirubinemia Male Middle Aged Spleen | ||
| 15 (58.6%) |
8471774 |
Human erythrocyte protein 4.2 deficiency associated with hemolytic anemia and a homozygous 40glutamic acid-->lysine substitution in the cytoplasmic domain of band 3 (band 3Montefiore). Rybicki AC, Qiu JJ, Musto S, Rosen NL, Nagel RL, Schwartz RS. Blood. 1993;81(8):2155-65. |
| Splenomegaly Hemolytic anemia Spherocytosis | ||
| EPB42 GAPDH | ||
| c|SUB|G|232|A p|SUB|E|40|K rs45562031 | ||
| Adult Anemia, Hemolytic Anion Exchange Protein 1, Erythrocyte Base Sequence Blood Proteins Cytoskeletal Proteins DNA Erythrocyte Deformability Erythrocyte Membrane Females Glyceraldehyde-3-Phosphate Dehydrogenases Homo sapiens Homozygote Membrane Proteins Molecular Sequence Data Peptide Fragments Pregnancy Spherocytes Splenomegaly | ||
| 16 (57.9%) |
9595784 |
[Video laparoscopic splenectomy in a patient with splenomegaly due to hereditary spherocytosis: report of two cases]. Machado MA, da Rocha JR, Bove C, Herman P, Machado MC. Rev Hosp Clin Fac Med Sao Paulo. 1997;52(5):276-8. |
| Splenomegaly Spherocytosis | ||
| Adult Females Homo sapiens Laparoscopy Male Splenectomy Splenomegaly Video Recording | ||
| 16 (57.9%) |
7967056 |
[Hereditary spherocytosis associated with non-Hodgkin's lymphoma in the spleen]. Arisawa K, Morita S, Kojima H, Inui A, Yoshino G, Hayashi Y, Kasuga M. Rinsho Ketsueki. 1994;35(9):871-5. |
| Splenomegaly Spherocytosis | ||
| DDIT3 | ||
| Antineoplastic Combined Chemotherapy Protocols Females Homo sapiens Lymphoma, Follicular Middle Aged Splenic Neoplasms | ||
| 16 (57.9%) |
448868 |
Hereditary spherocytosis with normal osmotic fragility after incubation. Is the autohemolysis test really obsolete? Fukagawa N, Friedman S, Gill FM, Schwartz E, Shaller C. JAMA. 1979;242(1):63-4. |
| Splenomegaly Reticulocytosis Spherocytosis | ||
| Child Child, Preschool Erythrocyte Membrane Erythrocytes Homo sapiens Male | ||
| 19 (56.4%) |
27566068 (5002123) |
Open-heart surgery using a centrifugal pump: a case of hereditary spherocytosis. Matsuzaki Y, Tomioka H, Saso M, Azuma T, Saito S, Aomi S, Yamazaki K. J Cardiothorac Surg. 2016;11(1):138. |
| Jaundice Splenomegaly Hemolytic anemia | ||
| Aortic Aneurysm Aortic Valve Insufficiency Cardiopulmonary Bypass Homo sapiens Male Middle Aged | ||
| 19 (56.4%) |
27108201 |
Disease-modifying influences of coexistent G6PD-deficiency, Gilbert syndrome and deletional alpha thalassemia in hereditary spherocytosis: A report of three cases. Jamwal M, Aggarwal A, Kumar V, Sharma P, Sachdeva MU, Bansal D, Malhotra P, Das R. Clin Chim Acta. 2016;458:51-4. |
| Jaundice Splenomegaly Hemolytic anemia | ||
| G6PD | ||
| Adult Females Homo sapiens Male Mutation Sequence Deletion alpha-Thalassemia |
Total: 27
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0005502 | Increased red cell osmotic fragility | Very frequent (99-80%) |
| HP:0000952 | Jaundice | Frequent (79-30%) |
| HP:0000980 | Pallor | Frequent (79-30%) |
| HP:0001081 | Cholelithiasis | Frequent (79-30%) |
| HP:0001324 | Muscle weakness | Frequent (79-30%) |
| HP:0001744 | Splenomegaly | Frequent (79-30%) |
| HP:0001903 | Anemia | Frequent (79-30%) |
| HP:0001923 | Reticulocytosis | Frequent (79-30%) |
| HP:0002240 | Hepatomegaly | Frequent (79-30%) |
| HP:0002904 | Hyperbilirubinemia | Frequent (79-30%) |
| HP:0004444 | Spherocytosis | Frequent (79-30%) |
| HP:0005525 | Spontaneous hemolytic crises | Frequent (79-30%) |
| HP:0011900 | Hypofibrinogenemia | Frequent (79-30%) |
| HP:0025548 | Increased mean corpuscular hemoglobin concentration | Frequent (79-30%) |
| HP:0100724 | Hypercoagulability | Frequent (79-30%) |
| HP:0001251 | Ataxia | Occasional (29-5%) |
| HP:0001945 | Fever | Occasional (29-5%) |
| HP:0001978 | Extramedullary hematopoiesis | Occasional (29-5%) |
| HP:0002027 | Abdominal pain | Occasional (29-5%) |
| HP:0003326 | Myalgia | Occasional (29-5%) |
| HP:0005130 | obsolete Restrictive heart failure | Occasional (29-5%) |
| HP:0025143 | Chills | Occasional (29-5%) |
| HP:0040186 | Maculopapular exanthema | Occasional (29-5%) |
| HP:0001510 | Growth delay | Very rare (4-1%) |
| HP:0001997 | Gout | Very rare (4-1%) |
| HP:0003270 | Abdominal distention | Very rare (4-1%) |
| HP:0200042 | Skin ulcer | Very rare (4-1%) |
Total: 88
| HPO ID | Term | # of case reports |
|---|---|---|
| HP:0000952 | Jaundice | 21 |
| HP:0001903 | Anemia | 20 |
| HP:0001744 | Splenomegaly | 19 |
| HP:0001878 | Hemolytic anemia | 15 |
| HP:0001978 | Extramedullary hematopoiesis | 13 |
| HP:0001081 | Cholelithiasis | 7 |
| HP:0002904 | Hyperbilirubinemia | 7 |
| HP:0002027 | Abdominal pain | 5 |
| HP:0001945 | Fever | 4 |
| HP:0004804 | Congenital hemolytic anemia | 4 |
| HP:0001747 | Accessory spleen | 3 |
| HP:0001909 | Leukemia | 3 |
| HP:0010783 | Erythema | 3 |
| HP:0000822 | Hypertension | 2 |
| HP:0001082 | Cholecystitis | 2 |
| HP:0001297 | Stroke | 2 |
| HP:0001638 | Cardiomyopathy | 2 |
| HP:0001873 | Thrombocytopenia | 2 |
| HP:0001894 | Thrombocytosis | 2 |
| HP:0002013 | Vomiting | 2 |
| HP:0002140 | Ischemic stroke | 2 |
| HP:0002202 | Pleural effusion | 2 |
| HP:0002204 | Pulmonary embolism | 2 |
| HP:0004444 | Spherocytosis | 2 |
| HP:0004445 | Elliptocytosis | 2 |
| HP:0004835 | Microspherocytosis | 2 |
| HP:0008282 | Unconjugated hyperbilirubinemia | 2 |
| HP:0011974 | Myelofibrosis | 2 |
| HP:0100806 | Sepsis | 2 |
| HP:0000011 | Neurogenic bladder | 1 |
| HP:0000100 | Nephrotic syndrome | 1 |
| HP:0000112 | Nephropathy | 1 |
| HP:0000126 | Hydronephrosis | 1 |
| HP:0000135 | Hypogonadism | 1 |
| HP:0000143 | Rectovaginal fistula | 1 |
| HP:0000238 | Hydrocephalus | 1 |
| HP:0000819 | Diabetes mellitus | 1 |
| HP:0000939 | Osteoporosis | 1 |
| HP:0000979 | Purpura | 1 |
| HP:0000989 | Pruritus | 1 |
| HP:0001028 | Hemangioma | 1 |
| HP:0001046 | Intermittent jaundice | 1 |
| HP:0001254 | Lethargy | 1 |
| HP:0001287 | Meningitis | 1 |
| HP:0001350 | Slurred speech | 1 |
| HP:0001394 | Cirrhosis | 1 |
| HP:0001406 | Intrahepatic cholestasis | 1 |
| HP:0001409 | Portal hypertension | 1 |
| HP:0001433 | Hepatosplenomegaly | 1 |
| HP:0001541 | Ascites | 1 |
| HP:0001635 | Congestive heart failure | 1 |
| HP:0001647 | Bicuspid aortic valve | 1 |
| HP:0001648 | Cor pulmonale | 1 |
| HP:0001655 | Patent foramen ovale | 1 |
| HP:0001733 | Pancreatitis | 1 |
| HP:0001876 | Pancytopenia | 1 |
| HP:0001889 | Megaloblastic anemia | 1 |
| HP:0001927 | Acanthocytosis | 1 |
| HP:0001931 | Hypochromic anemia | 1 |
| HP:0001971 | Hypersplenism | 1 |
| HP:0002098 | Respiratory distress | 1 |
| HP:0002099 | Asthma | 1 |
| HP:0002148 | Hypophosphatemia | 1 |
| HP:0002301 | Hemiplegia | 1 |
| HP:0002315 | Headache | 1 |
| HP:0002326 | Transient ischemic attack | 1 |
| HP:0002721 | Immunodeficiency | 1 |
| HP:0003265 | Neonatal hyperbilirubinemia | 1 |
| HP:0003756 | Skeletal myopathy | 1 |
| HP:0004870 | Chronic hemolytic anemia | 1 |
| HP:0004936 | Venous thrombosis | 1 |
| HP:0005110 | Atrial fibrillation | 1 |
| HP:0005521 | Disseminated intravascular coagulation | 1 |
| HP:0006846 | Acute encephalopathy | 1 |
| HP:0009830 | Peripheral neuropathy | 1 |
| HP:0012151 | Hemothorax | 1 |
| HP:0012330 | Pyelonephritis | 1 |
| HP:0012378 | Fatigue | 1 |
| HP:0025143 | Chills | 1 |
| HP:0025268 | Stuttering | 1 |
| HP:0030834 | Shoulder pain | 1 |
| HP:0031273 | Shock | 1 |
| HP:0032366 | Positive direct antiglobulin test | 1 |
| HP:0100727 | Histiocytosis | 1 |
| HP:0100749 | Chest pain | 1 |
| HP:0200023 | Priapism | 1 |
| HP:0410019 | Epigastric pain | 1 |
| HP:0410288 | Hyperamylasemia | 1 |
Total: 5