| Rank (Similarity) |
PMID (PMCID) |
|
|---|---|---|
| 11 (43.6%) |
18477219 |
Glomeruloid hemangioma. Yuri T, Yamazaki F, Takasu K, Shikata N, Tsubura A. Pathol Int. 2008;58(6):390-5. |
| Purpura Ascites Pleural effusion | ||
| CD34 CD68 PECAM1 | ||
| Biomarkers, Tumor Females Hemangioma Homo sapiens Middle Aged POEMS Syndrome Parotid Gland Sjogren's Syndrome Skin Neoplasms | ||
| 12 (40.6%) |
14673584 |
Multiple vascular abnormalities and a paradoxical combination of vitamin B12 deficiency and thrombocytosis in a case with POEMS syndrome. Lewerenz J, Gocht A, Hoeger PH, von den Driesch P, Eckert B, Lamszus K, Stuerenburg HJ, Methner A. J Neurol. 2003;250(12):1488-91. |
| Hypertension Thrombocytosis Arteriovenous fistula Vitamin B12 deficiency | ||
| MYOM2 VEGFA | ||
| Adult Females Homo sapiens Lung POEMS Syndrome Paraproteinemias Spinal Cord Spinal Cord Diseases Thrombocytosis Vascular Diseases Vascular Endothelial Growth Factor A Vitamin B 12 Deficiency | ||
| 13 (39.7%) |
1786657 |
[A case of Crow-Fukase syndrome with increased serum interleukin-6]. Hitoshi S, Okazawa H, Shimizu J, Suzuki K, Sakuta M. Rinsho Shinkeigaku. 1991;31(7):730-3. |
| Cyanosis Edema Thrombocytosis Increased circulating interleukin 6 | ||
| IL6 | ||
| Females Follow-Up Studies Hemangioma Homo sapiens Middle Aged POEMS Syndrome Skin Neoplasms Thrombosis | ||
| 14 (38.8%) |
25984208 (4421663) |
POEMS syndrome with renal plasmacytoma and classic polyarteritis nodosa: a case report. Jha PK, Vankalakunti M, Bonu R, Babu K, Ballal HS. NDT Plus. 2011;4(6):406-9. |
| Edema Ascites Thrombocytosis | ||
| 15 (38.2%) |
1888577 |
[A case of Crow-Fukase syndrome associated with idiopathic thrombocytopenic purpura]. Kawaguchi Y, Nagasato K, Yoshimura T, Motomura M, Tsujihata M, Nagataki S. No To Shinkei. 1991;43(4):377-80. |
| Edema Purpura | ||
| Adult Autoantibodies Autoimmune Diseases Axon Blood Platelets Edema Homo sapiens Male Nerve Degeneration Pigmentation Disorders Polyneuropathy Syndrome | ||
| 16 (38.0%) |
29279594 |
POEMS syndrome. Nyunt WWT, Remli R, Abdul Muttlib FA, Leong CF, Masir N, Tumian NR, Abdul Wahid SFS. Malays J Pathol. 2017;39(3):297-303. |
| Polyneuropathy Hepatosplenomegaly Thrombocytosis | ||
| Anti-Inflammatory Agents Females Homo sapiens Myeloablative Agonists POEMS Syndrome | ||
| 16 (38.0%) |
25332557 |
Multicentric, Hyaline Vascular Variant of Castleman's Syndrome. Mukta V, Susmitha C, Kar R, Basu D, Das AK. Indian J Hematol Blood Transfus. 2014;30(Suppl 1):126-30. |
| Polyneuropathy Hepatosplenomegaly Plasmacytosis | ||
| 16 (38.0%) |
19943169 |
Intracranial hemangiomas in a patient with POEMS syndrome. Maurer GD, Schittenhelm J, Ernemann U, Kempf VA, Ritz R, Weller M, Schmidt F. J Neurol. 2010;257(3):484-7. |
| Hemangioma Thrombocytosis Hepatomegaly | ||
| Biological Markers Brain Brain Neoplasms Diplopia Females Hemangioma, Cavernous, Central Nervous System Homo sapiens Low Vision Magnetic Resonance Imaging Middle Aged Neurosurgical Procedures POEMS Syndrome Peripheral Nervous System Diseases Plasmacytoma Up-Regulation (Physiology) Vascular Endothelial Growth Factor A | ||
| 19 (37.7%) |
14503355 |
[A case of anaphylactoid shock occurring immediately after the initiation of second intravenous administration of high-dose immunoglobulin (IVIg) in a patient with Crow-Fukase syndrome]. Takahashi T, Ono S, Ogawa K, Tamura M, Mizutani T. Rinsho Shinkeigaku. 2003;43(6):350-5. |
| Cyanosis Edema Hepatosplenomegaly | ||
| VEGFA | ||
| Biological Markers Capillary Permeability Endothelial Growth Factors Females Homo sapiens Intercellular Signaling Peptides and Proteins Lymphocyte Activation Lymphokines Middle Aged POEMS Syndrome Pathologic Neovascularization Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factors | ||
| 20 (37.6%) |
20403034 |
POEMS syndrome with idiopathic portal hypertension: autopsy case and review of the literature. Inoue R, Nakazawa A, Tsukada N, Katoh Y, Nagao T, Nakanuma Y, Mukai K. Pathol Int. 2010;60(4):316-20. |
| Edema Splenomegaly Portal fibrosis | ||
| MYOM2 VEGFA | ||
| Adult Fatal Outcome Females Fibrosis Hepatomegaly Homo sapiens Liver Middle Aged POEMS Syndrome Portal Hypertension |
Total: 46
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0001271 | Polyneuropathy | Obligate (100%) |
| HP:0000135 | Hypogonadism | Very frequent (99-80%) |
| HP:0000818 | Abnormality of the endocrine system | Very frequent (99-80%) |
| HP:0003271 | Visceromegaly | Very frequent (99-80%) |
| HP:0005523 | Lymphoproliferative disorder | Very frequent (99-80%) |
| HP:0010702 | Increased antibody level in blood | Very frequent (99-80%) |
| HP:0011122 | Abnormality of skin physiology | Very frequent (99-80%) |
| HP:0000771 | Gynecomastia | Frequent (79-30%) |
| HP:0000819 | Diabetes mellitus | Frequent (79-30%) |
| HP:0000821 | Hypothyroidism | Frequent (79-30%) |
| HP:0000953 | Hyperpigmentation of the skin | Frequent (79-30%) |
| HP:0000969 | Edema | Frequent (79-30%) |
| HP:0000998 | Hypertrichosis | Frequent (79-30%) |
| HP:0001028 | Hemangioma | Frequent (79-30%) |
| HP:0001072 | Thickened skin | Frequent (79-30%) |
| HP:0001085 | Papilledema | Frequent (79-30%) |
| HP:0001284 | Areflexia | Frequent (79-30%) |
| HP:0001324 | Muscle weakness | Frequent (79-30%) |
| HP:0001541 | Ascites | Frequent (79-30%) |
| HP:0001698 | Pericardial effusion | Frequent (79-30%) |
| HP:0001820 | Leukonychia | Frequent (79-30%) |
| HP:0001824 | Weight loss | Frequent (79-30%) |
| HP:0001894 | Thrombocytosis | Frequent (79-30%) |
| HP:0002092 | Pulmonary arterial hypertension | Frequent (79-30%) |
| HP:0002202 | Pleural effusion | Frequent (79-30%) |
| HP:0002694 | Sclerosis of skull base | Frequent (79-30%) |
| HP:0002716 | Lymphadenopathy | Frequent (79-30%) |
| HP:0003401 | Paresthesia | Frequent (79-30%) |
| HP:0004054 | Sclerosis of hand bone | Frequent (79-30%) |
| HP:0004576 | Sclerotic vertebral endplates | Frequent (79-30%) |
| HP:0004979 | Metaphyseal sclerosis | Frequent (79-30%) |
| HP:0008207 | Primary adrenal insufficiency | Frequent (79-30%) |
| HP:0012378 | Fatigue | Frequent (79-30%) |
| HP:0012531 | Pain | Frequent (79-30%) |
| HP:0100639 | Erectile abnormalities | Frequent (79-30%) |
| HP:0100759 | Clubbing of fingers | Frequent (79-30%) |
| HP:0100925 | Sclerosis of foot bone | Frequent (79-30%) |
| HP:0000870 | Prolactin excess | Occasional (29-5%) |
| HP:0001063 | Acrocyanosis | Occasional (29-5%) |
| HP:0001901 | Polycythemia | Occasional (29-5%) |
| HP:0002111 | Restrictive deficit on pulmonary function testing | Occasional (29-5%) |
| HP:0002747 | Respiratory insufficiency due to muscle weakness | Occasional (29-5%) |
| HP:0004420 | Arterial thrombosis | Occasional (29-5%) |
| HP:0004936 | Venous thrombosis | Occasional (29-5%) |
| HP:0009125 | Lipodystrophy | Occasional (29-5%) |
| HP:0100963 | Hyperesthesia | Occasional (29-5%) |
Total: 129
| HPO ID | Term | # of case reports |
|---|---|---|
| HP:0001271 | Polyneuropathy | 214 |
| HP:0000969 | Edema | 30 |
| HP:0009830 | Peripheral neuropathy | 26 |
| HP:0000822 | Hypertension | 20 |
| HP:0001541 | Ascites | 13 |
| HP:0002240 | Hepatomegaly | 13 |
| HP:0002716 | Lymphadenopathy | 13 |
| HP:0001433 | Hepatosplenomegaly | 12 |
| HP:0031357 | Glomeruloid hemangioma | 12 |
| HP:0001085 | Papilledema | 11 |
| HP:0000821 | Hypothyroidism | 10 |
| HP:0001744 | Splenomegaly | 9 |
| HP:0001894 | Thrombocytosis | 9 |
| HP:0000998 | Hypertrichosis | 8 |
| HP:0001297 | Stroke | 8 |
| HP:0000135 | Hypogonadism | 7 |
| HP:0012050 | Anasarca | 7 |
| HP:0001028 | Hemangioma | 5 |
| HP:0001409 | Portal hypertension | 5 |
| HP:0000846 | Adrenal insufficiency | 4 |
| HP:0001217 | Clubbing | 4 |
| HP:0005523 | Lymphoproliferative disorder | 4 |
| HP:0031047 | Paraproteinemia | 4 |
| HP:0100726 | Kaposi's sarcoma | 4 |
| HP:0000771 | Gynecomastia | 3 |
| HP:0000819 | Diabetes mellitus | 3 |
| HP:0001698 | Pericardial effusion | 3 |
| HP:0002094 | Dyspnea | 3 |
| HP:0002140 | Ischemic stroke | 3 |
| HP:0002202 | Pleural effusion | 3 |
| HP:0002878 | Respiratory failure | 3 |
| HP:0004420 | Arterial thrombosis | 3 |
| HP:0012398 | Peripheral edema | 3 |
| HP:0000093 | Proteinuria | 2 |
| HP:0000112 | Nephropathy | 2 |
| HP:0000622 | Blurred vision | 2 |
| HP:0000793 | Membranoproliferative glomerulonephritis | 2 |
| HP:0001138 | Optic neuropathy | 2 |
| HP:0001370 | Rheumatoid arthritis | 2 |
| HP:0001638 | Cardiomyopathy | 2 |
| HP:0001640 | Cardiomegaly | 2 |
| HP:0001873 | Thrombocytopenia | 2 |
| HP:0001952 | Glucose intolerance | 2 |
| HP:0002196 | Myelopathy | 2 |
| HP:0002721 | Immunodeficiency | 2 |
| HP:0003470 | Paralysis | 2 |
| HP:0004934 | Vascular calcification | 2 |
| HP:0004936 | Venous thrombosis | 2 |
| HP:0005306 | Capillary hemangioma | 2 |
| HP:0011505 | Cystoid macular edema | 2 |
| HP:0012089 | Arteritis | 2 |
| HP:0100778 | Cryoglobulinemia | 2 |
| HP:0100820 | Glomerulopathy | 2 |
| HP:0000044 | Hypogonadotrophic hypogonadism | 1 |
| HP:0000083 | Renal insufficiency | 1 |
| HP:0000097 | Focal segmental glomerulosclerosis | 1 |
| HP:0000100 | Nephrotic syndrome | 1 |
| HP:0000238 | Hydrocephalus | 1 |
| HP:0000572 | Visual loss | 1 |
| HP:0000802 | Impotence | 1 |
| HP:0000823 | Delayed puberty | 1 |
| HP:0000832 | Primary hypothyroidism | 1 |
| HP:0000843 | Hyperparathyroidism | 1 |
| HP:0000952 | Jaundice | 1 |
| HP:0000958 | Dry skin | 1 |
| HP:0000979 | Purpura | 1 |
| HP:0001289 | Confusion | 1 |
| HP:0001369 | Arthritis | 1 |
| HP:0001635 | Congestive heart failure | 1 |
| HP:0001658 | Myocardial infarction | 1 |
| HP:0001701 | Pericarditis | 1 |
| HP:0001824 | Weight loss | 1 |
| HP:0001876 | Pancytopenia | 1 |
| HP:0001903 | Anemia | 1 |
| HP:0001909 | Leukemia | 1 |
| HP:0001919 | Acute kidney injury | 1 |
| HP:0001953 | Diabetic ketoacidosis | 1 |
| HP:0002028 | Chronic diarrhea | 1 |
| HP:0002102 | Pleuritis | 1 |
| HP:0002170 | Intracranial hemorrhage | 1 |
| HP:0002273 | Tetraparesis | 1 |
| HP:0002315 | Headache | 1 |
| HP:0002326 | Transient ischemic attack | 1 |
| HP:0002516 | Increased intracranial pressure | 1 |
| HP:0002664 | Neoplasm | 1 |
| HP:0002754 | Osteomyelitis | 1 |
| HP:0002797 | Osteolysis | 1 |
| HP:0002901 | Hypocalcemia | 1 |
| HP:0003207 | Arterial calcification | 1 |
| HP:0003270 | Abdominal distention | 1 |
| HP:0003271 | Visceromegaly | 1 |
| HP:0003447 | Axonal loss | 1 |
| HP:0003450 | Axonal regeneration | 1 |
| HP:0003552 | Muscle stiffness | 1 |
| HP:0004947 | Arteriovenous fistula | 1 |
| HP:0005162 | Left ventricular dysfunction | 1 |
| HP:0005521 | Disseminated intravascular coagulation | 1 |
| HP:0006597 | Diaphragmatic paralysis | 1 |
| HP:0007131 | Acute demyelinating polyneuropathy | 1 |
| HP:0007133 | Progressive peripheral neuropathy | 1 |
| HP:0007141 | Sensorimotor neuropathy | 1 |
| HP:0007305 | CNS demyelination | 1 |
| HP:0007663 | Reduced visual acuity | 1 |
| HP:0008462 | Cervical instability | 1 |
| HP:0008720 | Primary testicular failure | 1 |
| HP:0010310 | Chylothorax | 1 |
| HP:0010741 | Pedal edema | 1 |
| HP:0011506 | Choroidal neovascularization | 1 |
| HP:0011510 | Drusen | 1 |
| HP:0012115 | Hepatitis | 1 |
| HP:0012474 | Carotid artery occlusion | 1 |
| HP:0012595 | Mild proteinuria | 1 |
| HP:0012722 | Heart block | 1 |
| HP:0025168 | Left ventricular diastolic dysfunction | 1 |
| HP:0025406 | Asthenia | 1 |
| HP:0025615 | Abscess | 1 |
| HP:0030150 | Plasmacytosis | 1 |
| HP:0030169 | Gastric varix | 1 |
| HP:0030783 | Increased serum interleukin-6 | 1 |
| HP:0030880 | Raynaud phenomenon | 1 |
| HP:0031273 | Shock | 1 |
| HP:0031284 | Flushing | 1 |
| HP:0031287 | Seborrheic keratosis | 1 |
| HP:0032252 | Granuloma | 1 |
| HP:0040049 | Macular edema | 1 |
| HP:0100502 | Vitamin B12 deficiency | 1 |
| HP:0100774 | Hyperostosis | 1 |
| HP:0200034 | Papule | 1 |
| HP:0200042 | Skin ulcer | 1 |
Total: 0
| Gene Symbol | Gene Name | Entrez Gene ID |
|---|