| Rank (Similarity) |
PMID (PMCID) |
|
|---|---|---|
| 1 (56.2%) |
3587993 |
[Familial hemophagocytic lymphohistiocytosis (case report)]. Fuchs WA, Guggenbichler JP. Padiatr Padol. 1987;22(1):67-72. |
| Splenomegaly Hemolytic anemia Hyperbilirubinemia | ||
| Anemia, Hemolytic, Congenital Differential Diagnosis Disseminated Intravascular Coagulation Females Histiocytes Homo sapiens Infant Liver Lymphatic Diseases Lymphocyte Phagocytosis Spleen | ||
| 2 (55.1%) |
26881603 |
Langerhans cell histiocytosis diagnosed by FNAC of lymph nodes. Patne SC, Dwivedi S, Katiyar R, Gupta V, Gupta AK. J Cancer Res Ther. 2015;11(4):1028. |
| Hepatosplenomegaly Anemia Fever | ||
| CD1A S100A1 | ||
| Child, Preschool Cytodiagnosis Histiocytosis, Langerhans-Cell Homo sapiens Male | ||
| 2 (55.1%) |
19785312 |
Langerhans cell histiocytosis, a case of Letterer Siwe disease. Pant C, Madonia P, Bahna SL, Bass PF, Jeroudi M. J La State Med Soc. 2009;161(4):211-2. |
| Hepatosplenomegaly Anemia Fever | ||
| CDA | ||
| Antineoplastic Agents Child Combination Drug Therapy Histiocytosis, Langerhans-Cell Homo sapiens Male Salvage Therapy Skin | ||
| 4 (52.7%) |
7350706 |
Circulatory control of splenic hyperfunction in children with peripheral blood dyscrasia. Witte CL, Corrigan JJ Jr, Witte MH, Van Wyck DB, O'Mara RE, Woolfenden JM. Surg Gynecol Obstet. 1980;150(1):75-80. |
| Purpura Splenomegaly Hemolytic anemia | ||
| Blood Cell Count Child Child, Preschool Females Follow-Up Studies Hematological Disease Homo sapiens Hypersplenism Ligation Male Spleen Splenectomy | ||
| 5 (50.0%) |
27621925 (5004507) |
Pericardial Effusion in Langerhans Cell Histiocytosis: A Case Report. Gholami N. Iran Red Crescent Med J. 2016;18(6):e25604. |
| Skin rash Splenomegaly Anemia | ||
| 6 (49.7%) |
22031119 |
A rare case of neonatal systemic xanthogranulomatosis with severe hepatic disease and metachronous skin involvement. Papadakis V, Volonaki E, Katsibardi K, Stefanaki K, Valari M, Anagnostakou M, Polychronopoulou S. J Pediatr Hematol Oncol. 2012;34(3):226-8. |
| Jaundice Hepatosplenomegaly Pancytopenia Fever | ||
| Hepatomegaly Homo sapiens Immunosuppressive Agents Infant, Newborn Juvenile Xanthogranuloma Male Pancytopenia | ||
| 7 (48.9%) |
21350822 |
Juvenile myelomonocytic leukemia characterized by cutaneous lesion containing Langerhans cell histiocytosis-like cells. Ozono S, Inada H, Nakagawa SI, Ueda K, Matsumura H, Kojima S, Koga H, Hashimoto T, Oshima K, Matsuishi T. Int J Hematol. 2011;93(3):389-393. |
| Hepatosplenomegaly Anemia | ||
| CD1A CD207 CD68 CSF2 MPO NRAS | ||
| Asians Bone Marrow Transplantation Child, Preschool Dermis Graft Survival Histiocytosis, Langerhans-Cell Homo sapiens Japan Juvenile Myelomonocytic Leukemia Male Skin Neoplasms Transplantation, Homologous | ||
| 7 (48.9%) |
20000879 |
Cutaneous xanthogranulomas, hepatosplenomegaly, anemia, and thrombocytopenia as presenting signs of juvenile myelomonocytic leukemia. Cham E, Siegel D, Ruben BS. Am J Clin Dermatol. 2010;11(1):67-71. |
| Hepatosplenomegaly Anemia | ||
| NF1 | ||
| Anemia Antimetabolites Hepatomegaly Homo sapiens Infant Juvenile Myelomonocytic Leukemia Juvenile Xanthogranuloma Male Splenomegaly Thrombocytopenia | ||
| 7 (48.9%) |
16933727 |
Disseminated Langerhans cell histiocytosis-an interesting case report with concise review of literature. Chatterjee T, Naithani R, Agrawal N, Bhattacharya J, Bhattacharya M, Dutta P, Pati HP, Mahapatra M, Choudhary VP. Indian J Pathol Microbiol. 2006;49(2):248-50. |
| Anemia Hepatomegaly | ||
| CD1A CD68 | ||
| Antigens, CD1 Antigens, Differentiation, Myelomonocytic CD Antigens Child, Preschool Histiocytosis, Langerhans-Cell Homo sapiens Immunohistochemistry Male S100 Proteins | ||
| 7 (48.9%) |
9408765 |
Congenital systemic Langerhans cell histiocytosis (report of two cases). Stiakaki E, Giannakopoulou C, Kouvidi E, Bolonaki E, Kambourakis A, Lydaki E, Kalmanti M. Haematologia (Budap). 1997;28(4):215-22. |
| Hepatosplenomegaly Anemia | ||
| CD1C S100A1 | ||
| Antigens, CD1 Biopsy Females Histiocytes Histiocytosis, Langerhans-Cell Homo sapiens Infant, Newborn Male Necrosis Radiography, Thoracic Remission Induction S100 Proteins Skin |
Total: 0
| HPO ID | Term | Frequency |
|---|
Total: 209
| HPO ID | Term | # of case reports |
|---|---|---|
| HP:0000873 | Diabetes insipidus | 48 |
| HP:0032252 | Granuloma | 35 |
| HP:0100727 | Histiocytosis | 31 |
| HP:0002835 | Aspiration | 21 |
| HP:0002107 | Pneumothorax | 15 |
| HP:0002664 | Neoplasm | 15 |
| HP:0100242 | Sarcoma | 12 |
| HP:0001909 | Leukemia | 11 |
| HP:0030731 | Carcinoma | 11 |
| HP:0002754 | Osteomyelitis | 10 |
| HP:0000822 | Hypertension | 9 |
| HP:0002108 | Spontaneous pneumothorax | 8 |
| HP:0200034 | Papule | 8 |
| HP:0002861 | Melanoma | 7 |
| HP:0100620 | Germinoma | 7 |
| HP:0001945 | Fever | 6 |
| HP:0002176 | Spinal cord compression | 6 |
| HP:0002955 | Granulomatosis | 6 |
| HP:0012315 | Histiocytoma | 6 |
| HP:0001251 | Ataxia | 5 |
| HP:0002206 | Pulmonary fibrosis | 5 |
| HP:0002488 | Acute leukemia | 5 |
| HP:0002878 | Respiratory failure | 5 |
| HP:0005523 | Lymphoproliferative disorder | 5 |
| HP:0025615 | Abscess | 5 |
| HP:0100646 | Thyroiditis | 5 |
| HP:0000819 | Diabetes mellitus | 4 |
| HP:0000832 | Primary hypothyroidism | 4 |
| HP:0000988 | Skin rash | 4 |
| HP:0001875 | Neutropenia | 4 |
| HP:0002097 | Emphysema | 4 |
| HP:0002240 | Hepatomegaly | 4 |
| HP:0002716 | Lymphadenopathy | 4 |
| HP:0100658 | Cellulitis | 4 |
| HP:0000704 | Periodontitis | 3 |
| HP:0000853 | Goiter | 3 |
| HP:0001250 | Seizures | 3 |
| HP:0001880 | Eosinophilia | 3 |
| HP:0002090 | Pneumonia | 3 |
| HP:0002243 | Protein-losing enteropathy | 3 |
| HP:0002721 | Immunodeficiency | 3 |
| HP:0002797 | Osteolysis | 3 |
| HP:0002860 | Squamous cell carcinoma | 3 |
| HP:0002863 | Myelodysplasia | 3 |
| HP:0003072 | Hypercalcemia | 3 |
| HP:0003418 | Back pain | 3 |
| HP:0032445 | Pulmonary cyst | 3 |
| HP:0040075 | Hypopituitarism | 3 |
| HP:0000238 | Hydrocephalus | 2 |
| HP:0000473 | Torticollis | 2 |
| HP:0000651 | Diplopia | 2 |
| HP:0000824 | Growth hormone deficiency | 2 |
| HP:0000843 | Hyperparathyroidism | 2 |
| HP:0000952 | Jaundice | 2 |
| HP:0000964 | Eczema | 2 |
| HP:0000989 | Pruritus | 2 |
| HP:0001394 | Cirrhosis | 2 |
| HP:0001396 | Cholestasis | 2 |
| HP:0001433 | Hepatosplenomegaly | 2 |
| HP:0001482 | Subcutaneous nodule | 2 |
| HP:0001744 | Splenomegaly | 2 |
| HP:0001806 | Onycholysis | 2 |
| HP:0001818 | Paronychia | 2 |
| HP:0001876 | Pancytopenia | 2 |
| HP:0001903 | Anemia | 2 |
| HP:0002027 | Abdominal pain | 2 |
| HP:0002098 | Respiratory distress | 2 |
| HP:0002113 | Pulmonary infiltrates | 2 |
| HP:0002202 | Pleural effusion | 2 |
| HP:0002321 | Vertigo | 2 |
| HP:0002613 | Biliary cirrhosis | 2 |
| HP:0002650 | Scoliosis | 2 |
| HP:0003974 | Absent radius | 2 |
| HP:0009792 | Teratoma | 2 |
| HP:0009797 | Cholesteatoma | 2 |
| HP:0010566 | Hamartoma | 2 |
| HP:0010783 | Erythema | 2 |
| HP:0012115 | Hepatitis | 2 |
| HP:0012735 | Cough | 2 |
| HP:0025421 | Pneumomediastinum | 2 |
| HP:0100584 | Endocarditis | 2 |
| HP:0000020 | Urinary incontinence | 1 |
| HP:0000103 | Polyuria | 1 |
| HP:0000135 | Hypogonadism | 1 |
| HP:0000141 | Amenorrhea | 1 |
| HP:0000155 | Oral ulcer | 1 |
| HP:0000360 | Tinnitus | 1 |
| HP:0000518 | Cataract | 1 |
| HP:0000572 | Visual loss | 1 |
| HP:0000589 | Coloboma | 1 |
| HP:0000613 | Photophobia | 1 |
| HP:0000639 | Nystagmus | 1 |
| HP:0000668 | Hypodontia | 1 |
| HP:0000691 | Microdontia | 1 |
| HP:0000821 | Hypothyroidism | 1 |
| HP:0000829 | Hypoparathyroidism | 1 |
| HP:0000830 | Anterior hypopituitarism | 1 |
| HP:0000839 | Pituitary dwarfism | 1 |
| HP:0000939 | Osteoporosis | 1 |
| HP:0000962 | Hyperkeratosis | 1 |
| HP:0000967 | Petechiae | 1 |
| HP:0000969 | Edema | 1 |
| HP:0000991 | Xanthomatosis | 1 |
| HP:0000995 | Melanocytic nevus | 1 |
| HP:0001019 | Erythroderma | 1 |
| HP:0001025 | Urticaria | 1 |
| HP:0001028 | Hemangioma | 1 |
| HP:0001051 | Seborrheic dermatitis | 1 |
| HP:0001114 | Xanthelasma | 1 |
| HP:0001138 | Optic neuropathy | 1 |
| HP:0001271 | Polyneuropathy | 1 |
| HP:0001272 | Cerebellar atrophy | 1 |
| HP:0001288 | Gait disturbance | 1 |
| HP:0001289 | Confusion | 1 |
| HP:0001297 | Stroke | 1 |
| HP:0001409 | Portal hypertension | 1 |
| HP:0001513 | Obesity | 1 |
| HP:0001607 | Subglottic stenosis | 1 |
| HP:0001698 | Pericardial effusion | 1 |
| HP:0001701 | Pericarditis | 1 |
| HP:0001733 | Pancreatitis | 1 |
| HP:0001735 | Acute pancreatitis | 1 |
| HP:0001824 | Weight loss | 1 |
| HP:0001889 | Megaloblastic anemia | 1 |
| HP:0001952 | Glucose intolerance | 1 |
| HP:0001959 | Polydipsia | 1 |
| HP:0001974 | Leukocytosis | 1 |
| HP:0001978 | Extramedullary hematopoiesis | 1 |
| HP:0002013 | Vomiting | 1 |
| HP:0002014 | Diarrhea | 1 |
| HP:0002015 | Dysphagia | 1 |
| HP:0002028 | Chronic diarrhea | 1 |
| HP:0002041 | Intractable diarrhea | 1 |
| HP:0002073 | Progressive cerebellar ataxia | 1 |
| HP:0002105 | Hemoptysis | 1 |
| HP:0002152 | Hyperproteinemia | 1 |
| HP:0002180 | Neurodegeneration | 1 |
| HP:0002313 | Spastic paraparesis | 1 |
| HP:0002315 | Headache | 1 |
| HP:0002318 | Cervical myelopathy | 1 |
| HP:0002451 | Limb dystonia | 1 |
| HP:0002573 | Hematochezia | 1 |
| HP:0002580 | Volvulus | 1 |
| HP:0002653 | Bone pain | 1 |
| HP:0002668 | Paraganglioma | 1 |
| HP:0002715 | Abnormality of the immune system | 1 |
| HP:0002719 | Recurrent infections | 1 |
| HP:0002729 | Follicular hyperplasia | 1 |
| HP:0002756 | Pathologic fracture | 1 |
| HP:0002875 | Exertional dyspnea | 1 |
| HP:0003401 | Paresthesia | 1 |
| HP:0003470 | Paralysis | 1 |
| HP:0003651 | Foam cells | 1 |
| HP:0004322 | Short stature | 1 |
| HP:0004787 | Fulminant hepatitis | 1 |
| HP:0005206 | Pancreatic pseudocyst | 1 |
| HP:0005263 | Gastritis | 1 |
| HP:0005387 | Combined immunodeficiency | 1 |
| HP:0005912 | Biliary atresia | 1 |
| HP:0006280 | Chronic pancreatitis | 1 |
| HP:0007274 | Recurrent bacterial meningitis | 1 |
| HP:0007787 | Posterior subcapsular cataract | 1 |
| HP:0010447 | Anal fistula | 1 |
| HP:0010550 | Paraplegia | 1 |
| HP:0010980 | Hyperlipoproteinemia | 1 |
| HP:0011349 | Abducens palsy | 1 |
| HP:0011497 | Iris neovascularization | 1 |
| HP:0011900 | Hypofibrinogenemia | 1 |
| HP:0011946 | Bronchiolitis obliterans | 1 |
| HP:0011950 | Bronchiolitis | 1 |
| HP:0011951 | Aspiration pneumonia | 1 |
| HP:0011974 | Myelofibrosis | 1 |
| HP:0012108 | Open angle glaucoma | 1 |
| HP:0012311 | Monocytosis | 1 |
| HP:0012593 | Nephrotic range proteinuria | 1 |
| HP:0012740 | Papilloma | 1 |
| HP:0012798 | Pulmonary lymphangiomyomatosis | 1 |
| HP:0020073 | Hypopigmented macule | 1 |
| HP:0025084 | Folliculitis | 1 |
| HP:0025388 | Thyroid nodule | 1 |
| HP:0025402 | Square-wave jerks | 1 |
| HP:0025636 | Endometritis | 1 |
| HP:0030065 | Primitive neuroectodermal tumor | 1 |
| HP:0030166 | Night sweats | 1 |
| HP:0030350 | Erythematous papule | 1 |
| HP:0030426 | Ossifying fibroma | 1 |
| HP:0030430 | Neuroma | 1 |
| HP:0030766 | Ear pain | 1 |
| HP:0030838 | Hip pain | 1 |
| HP:0031047 | Paraproteinemia | 1 |
| HP:0031273 | Shock | 1 |
| HP:0031364 | Ecchymosis | 1 |
| HP:0031625 | Pseudoaneurysm | 1 |
| HP:0031846 | Femur fracture | 1 |
| HP:0032163 | Molluscum contagiosum | 1 |
| HP:0032204 | Chronic active Epstein-Barr virus infection | 1 |
| HP:0032282 | Contact dermatitis | 1 |
| HP:0040313 | Oligoarthritis | 1 |
| HP:0100246 | Osteoma | 1 |
| HP:0100279 | Ulcerative colitis | 1 |
| HP:0100621 | Dysgerminoma | 1 |
| HP:0100699 | Scarring | 1 |
| HP:0100721 | Mediastinal lymphadenopathy | 1 |
| HP:0100749 | Chest pain | 1 |
| HP:0100829 | Galactorrhea | 1 |
| HP:0200036 | Skin nodule | 1 |
| HP:0200039 | Pustule | 1 |
| HP:0200040 | Epidermoid cyst | 1 |
| HP:0410017 | Otitis externa | 1 |
Total: 0
| Gene Symbol | Gene Name | Entrez Gene ID |
|---|