| Rank (Similarity) |
PMID (PMCID) |
|
|---|---|---|
| 445 (5.0%) |
8913726 |
Constitutional trisomy 8 as first mutation in multistep carcinogenesis: clinical, cytogenetic, and molecular data on three cases. Seghezzi L, Maserati E, Minelli A, Dellavecchia C, Addis P, Locatelli F, Angioni A, Balloni P, Miano C, Cavalli P, Danesino C, Pasquali F. Genes Chromosomes Cancer. 1996;17(2):94-101. |
| Neoplasm | ||
| GSR LUZP4 | ||
| Aspartic Acid Endopeptidases Child, Preschool Chromosomes, Human, Pair 8 Females Fibroblasts Glutathione Reductase Hematologic Neoplasms Homo sapiens Infant Malate Dehydrogenase Male Mosaicism Mutation Polymerase Chain Reaction Precursor Cell Lymphoblastic Leukemia Lymphoma Primary Myelofibrosis Trisomy | ||
| 445 (5.0%) |
8575594 |
Pulmonary fibrosis and sea-blue histiocyte infiltration in a patient with primary myelofibrosis. Yamauchi K, Shimamura K. Eur Respir J. 1995;8(9):1620-3. |
| Pulmonary fibrosis | ||
| Biopsy Fatal Outcome Homo sapiens Male Primary Myelofibrosis Pulmonary Fibrosis Sea-Blue Histiocyte Syndrome | ||
| 445 (5.0%) |
6847265 |
Arthritis due to synovial involvement by extramedullary haematopoiesis in myelofibrosis with myeloid metaplasia. Heinicke MH, Zarrabi MH, Gorevic PD. Ann Rheum Dis. 1983;42(2):196-200. |
| Arthritis | ||
| Arthritis Hematopoiesis Homo sapiens Male Middle Aged Primary Myelofibrosis Synovial Membrane | ||
| 445 (5.0%) |
6720738 |
Cutaneous extramedullary hematopoiesis following splenectomy for idiopathic myelofibrosis. Hocking WG, Lazar GS, Lipsett JA, Busuttil RW. Am J Med. 1984;76(5):956-8. |
| Cellulitis | ||
| Females Hematopoiesis Homo sapiens Male Middle Aged Primary Myelofibrosis Splenectomy | ||
| 445 (5.0%) |
6638012 |
Intracranial myeloid metaplasia: diagnosis by CT and Fe52 scans and treatment by cranial irradiation. Cornfield DB, Shipkin P, Alavi A, Becker J, Peyster R. Am J Hematol. 1983;15(3):273-8. |
| Dementia | ||
| Brain Brain Diseases Dementia Females Hepatomegaly Homo sapiens Iron Radioisotopes Middle Aged Primary Myelofibrosis Radionuclide Imaging Splenomegaly X-Ray Computed Tomography | ||
| 445 (5.0%) |
6131125 |
Agnogenic myeloid metaplasia with polyarteritis. Connelly TJ, Abruzzo JL, Schwab RH. J Rheumatol. 1982;9(6):954-6. |
| Arthritis | ||
| Females Homo sapiens Polyarteritis Nodosa Primary Myelofibrosis Radionuclide Imaging Skeleton Synovial Fluid | ||
| 445 (5.0%) |
441867 |
Agnogenic myeloid metaplasia and spinal cord compression. Jacobs P, Dubovsky D, Commerford P, Price S, Handler L. S Afr Med J. 1979;55(7):256-9. |
| Spinal cord compression | ||
| Homo sapiens Male Middle Aged Primary Myelofibrosis |
Total: 36
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0005561 | Abnormality of bone marrow cell morphology | Very frequent (99-80%) |
| HP:0000980 | Pallor | Frequent (79-30%) |
| HP:0001433 | Hepatosplenomegaly | Frequent (79-30%) |
| HP:0001744 | Splenomegaly | Frequent (79-30%) |
| HP:0001871 | Abnormality of blood and blood-forming tissues | Frequent (79-30%) |
| HP:0001873 | Thrombocytopenia | Frequent (79-30%) |
| HP:0001903 | Anemia | Frequent (79-30%) |
| HP:0002240 | Hepatomegaly | Frequent (79-30%) |
| HP:0012143 | Abnormal megakaryocyte morphology | Frequent (79-30%) |
| HP:0012378 | Fatigue | Frequent (79-30%) |
| HP:0025142 | Constitutional symptom | Frequent (79-30%) |
| HP:0000967 | Petechiae | Occasional (29-5%) |
| HP:0000979 | Purpura | Occasional (29-5%) |
| HP:0001409 | Portal hypertension | Occasional (29-5%) |
| HP:0001876 | Pancytopenia | Occasional (29-5%) |
| HP:0001892 | Abnormal bleeding | Occasional (29-5%) |
| HP:0001894 | Thrombocytosis | Occasional (29-5%) |
| HP:0001945 | Fever | Occasional (29-5%) |
| HP:0001974 | Leukocytosis | Occasional (29-5%) |
| HP:0001977 | Abnormal thrombosis | Occasional (29-5%) |
| HP:0001978 | Extramedullary hematopoiesis | Occasional (29-5%) |
| HP:0002039 | Anorexia | Occasional (29-5%) |
| HP:0002716 | Lymphadenopathy | Occasional (29-5%) |
| HP:0003388 | Easy fatigability | Occasional (29-5%) |
| HP:0004420 | Arterial thrombosis | Occasional (29-5%) |
| HP:0004447 | Poikilocytosis | Occasional (29-5%) |
| HP:0004936 | Venous thrombosis | Occasional (29-5%) |
| HP:0011134 | Low-grade fever | Occasional (29-5%) |
| HP:0030157 | Flank pain | Occasional (29-5%) |
| HP:0031020 | Bone marrow hypercellularity | Occasional (29-5%) |
| HP:0031364 | Ecchymosis | Occasional (29-5%) |
| HP:0001028 | Hemangioma | Very rare (4-1%) |
| HP:0004326 | Cachexia | Very rare (4-1%) |
| HP:0004377 | Hematological neoplasm | Very rare (4-1%) |
| HP:0025435 | Increased lactate dehydrogenase activity | Very rare (4-1%) |
| HP:0030057 | Autoimmune antibody positivity | Excluded (0%) |
Total: 109
| HPO ID | Term | # of case reports |
|---|---|---|
| HP:0011974 | Myelofibrosis | 53 |
| HP:0001978 | Extramedullary hematopoiesis | 49 |
| HP:0001744 | Splenomegaly | 36 |
| HP:0001909 | Leukemia | 21 |
| HP:0001903 | Anemia | 19 |
| HP:0001876 | Pancytopenia | 11 |
| HP:0001409 | Portal hypertension | 10 |
| HP:0001541 | Ascites | 10 |
| HP:0000822 | Hypertension | 7 |
| HP:0001433 | Hepatosplenomegaly | 7 |
| HP:0002094 | Dyspnea | 7 |
| HP:0001894 | Thrombocytosis | 6 |
| HP:0002202 | Pleural effusion | 6 |
| HP:0002488 | Acute leukemia | 6 |
| HP:0001945 | Fever | 5 |
| HP:0002835 | Aspiration | 5 |
| HP:0001974 | Leukocytosis | 4 |
| HP:0004447 | Poikilocytosis | 4 |
| HP:0001370 | Rheumatoid arthritis | 3 |
| HP:0001698 | Pericardial effusion | 3 |
| HP:0001873 | Thrombocytopenia | 3 |
| HP:0002040 | Esophageal varix | 3 |
| HP:0002664 | Neoplasm | 3 |
| HP:0002716 | Lymphadenopathy | 3 |
| HP:0002863 | Myelodysplasia | 3 |
| HP:0003072 | Hypercalcemia | 3 |
| HP:0004936 | Venous thrombosis | 3 |
| HP:0000093 | Proteinuria | 2 |
| HP:0000979 | Purpura | 2 |
| HP:0001482 | Subcutaneous nodule | 2 |
| HP:0001824 | Weight loss | 2 |
| HP:0001878 | Hemolytic anemia | 2 |
| HP:0001880 | Eosinophilia | 2 |
| HP:0002176 | Spinal cord compression | 2 |
| HP:0002206 | Pulmonary fibrosis | 2 |
| HP:0002240 | Hepatomegaly | 2 |
| HP:0002653 | Bone pain | 2 |
| HP:0025142 | Constitutional symptom | 2 |
| HP:0030731 | Carcinoma | 2 |
| HP:0032147 | Erythromelalgia | 2 |
| HP:0000097 | Focal segmental glomerulosclerosis | 1 |
| HP:0000100 | Nephrotic syndrome | 1 |
| HP:0000126 | Hydronephrosis | 1 |
| HP:0000726 | Dementia | 1 |
| HP:0000790 | Hematuria | 1 |
| HP:0000980 | Pallor | 1 |
| HP:0000988 | Skin rash | 1 |
| HP:0001028 | Hemangioma | 1 |
| HP:0001289 | Confusion | 1 |
| HP:0001324 | Muscle weakness | 1 |
| HP:0001369 | Arthritis | 1 |
| HP:0001394 | Cirrhosis | 1 |
| HP:0001399 | Hepatic failure | 1 |
| HP:0001708 | Right ventricular failure | 1 |
| HP:0001746 | Asplenia | 1 |
| HP:0001882 | Leukopenia | 1 |
| HP:0001907 | Thromboembolism | 1 |
| HP:0002027 | Abdominal pain | 1 |
| HP:0002090 | Pneumonia | 1 |
| HP:0002098 | Respiratory distress | 1 |
| HP:0002204 | Pulmonary embolism | 1 |
| HP:0002205 | Recurrent respiratory infections | 1 |
| HP:0002239 | Gastrointestinal hemorrhage | 1 |
| HP:0002249 | Melena | 1 |
| HP:0002315 | Headache | 1 |
| HP:0002527 | Falls | 1 |
| HP:0002719 | Recurrent infections | 1 |
| HP:0002721 | Immunodeficiency | 1 |
| HP:0002878 | Respiratory failure | 1 |
| HP:0002901 | Hypocalcemia | 1 |
| HP:0002958 | Immune dysregulation | 1 |
| HP:0002960 | Autoimmunity | 1 |
| HP:0003080 | Hydroxyprolinuria | 1 |
| HP:0003201 | Rhabdomyolysis | 1 |
| HP:0003418 | Back pain | 1 |
| HP:0004445 | Elliptocytosis | 1 |
| HP:0005112 | Abdominal aortic aneurysm | 1 |
| HP:0005180 | Tricuspid regurgitation | 1 |
| HP:0005387 | Combined immunodeficiency | 1 |
| HP:0005523 | Lymphoproliferative disorder | 1 |
| HP:0006000 | Ureteral obstruction | 1 |
| HP:0007199 | Progressive spastic paraparesis | 1 |
| HP:0008940 | Generalized lymphadenopathy | 1 |
| HP:0012109 | Angle closure glaucoma | 1 |
| HP:0012138 | Granulocytic hyperplasia | 1 |
| HP:0012378 | Fatigue | 1 |
| HP:0012418 | Hypoxemia | 1 |
| HP:0012578 | Membranous nephropathy | 1 |
| HP:0012593 | Nephrotic range proteinuria | 1 |
| HP:0025388 | Thyroid nodule | 1 |
| HP:0025615 | Abscess | 1 |
| HP:0030150 | Plasmacytosis | 1 |
| HP:0030166 | Night sweats | 1 |
| HP:0030242 | Portal vein thrombosis | 1 |
| HP:0030666 | Retinal neovascularization | 1 |
| HP:0030667 | Peripheral retinal neovascularization | 1 |
| HP:0031047 | Paraproteinemia | 1 |
| HP:0031625 | Pseudoaneurysm | 1 |
| HP:0031864 | Bacteremia | 1 |
| HP:0032061 | Hypereosinophilia | 1 |
| HP:0032101 | Unusual infection | 1 |
| HP:0100584 | Endocarditis | 1 |
| HP:0100598 | Pulmonary edema | 1 |
| HP:0100644 | Melanonychia | 1 |
| HP:0100658 | Cellulitis | 1 |
| HP:0100820 | Glomerulopathy | 1 |
| HP:0200034 | Papule | 1 |
| HP:0200036 | Skin nodule | 1 |
| HP:0200084 | Giant cell hepatitis | 1 |